HOXC9

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12.

• Homeobox

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• {{cite journal | vauthors = Acampora D, D'Esposito M, Faiella A, Pannese M, Migliaccio E, Morelli F, Stornaiuolo A, Nigro V, Simeone A, Boncinelli E | title = The human HOX gene family | journal = Nucleic Acids Research | volume = 17 | issue = 24 | pages = 10385–402 | date = December 1989 | pmid = 2574852 | pmc = 335308 | doi = 10.1093/nar/17.24.10385 }}
• {{cite journal | vauthors = Boncinelli E, Acampora D, Pannese M, D'Esposito M, Somma R, Gaudino G, Stornaiuolo A, Cafiero M, Faiella A, Simeone A | title = Organization of human class I homeobox genes | journal = Genome | volume = 31 | issue = 2 | pages = 745–56 | year = 1990 | pmid = 2576652 | doi = 10.1139/g89-133 }}
• {{cite journal | vauthors = Rabin M, Ferguson-Smith A, Hart CP, Ruddle FH | title = Cognate homeo-box loci mapped on homologous human and mouse chromosomes | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 83 | issue = 23 | pages = 9104–8 | date = December 1986 | pmid = 2878432 | pmc = 387083 | doi = 10.1073/pnas.83.23.9104 | bibcode = 1986PNAS...83.9104R | doi-access = free }}
• {{cite journal | vauthors = Redline RW, Hudock P, MacFee M, Patterson P | title = Expression of AbdB-type homeobox genes in human tumors | journal = Laboratory Investigation; A Journal of Technical Methods and Pathology | volume = 71 | issue = 5 | pages = 663–70 | date = November 1994 | pmid = 7967520 }}
• {{cite journal | vauthors = Miano JM, Firulli AB, Olson EN, Hara P, Giachelli CM, Schwartz SM | title = Restricted expression of homeobox genes distinguishes fetal from adult human smooth muscle cells | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 93 | issue = 2 | pages = 900–5 | date = January 1996 | pmid = 8570656 | pmc = 40155 | doi = 10.1073/pnas.93.2.900 | bibcode = 1996PNAS...93..900M | doi-access = free }}
• {{cite journal | vauthors = Apiou F, Flagiello D, Cillo C, Malfoy B, Poupon MF, Dutrillaux B | title = Fine mapping of human HOX gene clusters | journal = Cytogenetics and Cell Genetics | volume = 73 | issue = 1–2 | pages = 114–5 | year = 1996 | pmid = 8646877 | doi = 10.1159/000134320 }}
• {{cite journal | vauthors = Flagiello D, Gibaud A, Dutrillaux B, Poupon MF, Malfoy B | title = Distinct patterns of all-trans retinoic acid dependent expression of HOXB and HOXC homeogenes in human embryonal and small-cell lung carcinoma cell lines | journal = FEBS Letters | volume = 415 | issue = 3 | pages = 263–7 | date = October 1997 | pmid = 9357979 | doi = 10.1016/S0014-5793(97)01118-6 | bibcode = 1997FEBSL.415..263F | s2cid = 26075369 }}
• {{cite journal | vauthors = Kosaki K, Kosaki R, Suzuki T, Yoshihashi H, Takahashi T, Sasaki K, Tomita M, McGinnis W, Matsuo N | title = Complete mutation analysis panel of the 39 human HOX genes | journal = Teratology | volume = 65 | issue = 2 | pages = 50–62 | date = February 2002 | pmid = 11857506 | doi = 10.1002/tera.10009 }}
• {{cite journal | vauthors = Luo L, Yang X, Takihara Y, Knoetgen H, Kessel M | title = The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions | journal = Nature | volume = 427 | issue = 6976 | pages = 749–53 | date = February 2004 | pmid = 14973489 | doi = 10.1038/nature02305 | bibcode = 2004Natur.427..749L | hdl = 11858/00-001M-0000-0012-EE32-1 | s2cid = 8020382 | hdl-access = free }}
• {{cite journal | vauthors = Okamoto OK, Oba-Shinjo SM, Lopes L, Nagahashi Marie SK | title = Expression of HOXC9 and E2F2 are up-regulated in CD133(+) cells isolated from human astrocytomas and associate with transformation of human astrocytes | journal = Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression | volume = 1769 | issue = 7–8 | pages = 437–42 | year = 2007 | pmid = 17588684 | doi = 10.1016/j.bbaexp.2007.05.002 }}

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• {{MeshName|HOXC9+protein,+human}}
• {{PDBe-KB2|P31274|Homeobox protein Hox-C9}}

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{{Transcription factors|g3}}

Category:Transcription factors

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