HPB

HPB may refer to:

Half Price Books, an American book retailer
Harvard Papers in Botany, a scientific journal
Health Promotion Board, a statutory board in Singapore for health promotion and disease prevention
Helena Petrovna Blavatsky (1831–1891), theosophist, writer and traveler
Hooper Bay Airport, in Alaska, United States (by IATA and FAA LID code)
Hrvatska poštanska banka, largest Croatian-owned bank
HPB (journal), journal of the International Hepato-Pancreato-Biliary Association
Hexaphenylbenzene