HST

• Harry S. Truman (1884–1972), 33rd president of the US
• Hunter S. Thompson (1937–2005), American journalist and author

• Hubble Space Telescope
• Harvard–MIT Program in Health Sciences and Technology
• History of science and technology
• High-speed telegraphy, a radiosport
• High-Speed Transfer, a USRobotics modem protocol
• Highstand systems tract, in the sequence stratigraphy branch of geology

• Hastings railway station, Melbourne (Station code), Australia
• Helicopter support team, in the US Marine Corps
• Helsinki City Transport (Swedish: {{lang|sv|Helsingfors stads trafikverk}})
• Heritage Shunters Trust, an English rail preservation society
• High-speed train, a type of rail transport
• InterCity 125 or High Speed Train, UK
• High Street (Glasgow) railway station (station code), Scotland
• High Sierra Trail, in California, US
• Homestead Air Reserve Base (IATA code), Florida, US
• USS Harry S. Truman (nickname: HST), an aircraft carrier of the US Navy
• High-speed transport, a type of amphibious assault ship

• Harmonized sales tax, in Canada
• Hawaii–Aleutian Standard Time (UTC−10)
• Hegemonic stability theory, in international relations
• Holden Street Theatres, Adelaide, Australia
• Hospital Santo Tomás, in Panama City, Panama
• Host Hotels & Resorts (stock ticker $HST), American REIT

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