Hazardous Substances Data Bank

{{Short description|Database of toxic compounds}}

{{Use dmy dates|date=January 2025}}

{{infobox biodatabase

|title = TOXNET: Hazardous Substances Data Bank

|logo =

|description = Chemical pharmacology and toxicology data

|scope = {{plainlist |

• 5000+ potentially hazardous chemicals
• human exposure
• pharmacology
• metabolism
• medications excreted in breastmilk{{cite book|url=https://toxnet.nlm.nih.gov/newtoxnet/lactmed.htm|title=Drugs and Lactation Database (LactMed)|website=toxnet.nlm.nih.gov|year=2006|publisher=National Library of Medicine (US)}}{{PD-notice}}
• industrial hygiene
• emergency handling
• environmental fate
• regulatory requirements
• related areas }}

|organism = Humans & other animals

|center = NCBI

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|author =

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|url = {{URL|https://www.nlm.nih.gov/toxnet/index.html}}

|citation = Fonger (1995)
Fonger, et al (2014)

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|license = Public domain

|versioning =

|frequency = Weekly

|curation = Peer-reviewed by the Scientific Review Panel

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The Hazardous Substances Data Bank (HSDB) was a toxicology database on the U.S. National Library of Medicine's (NLM) Toxicology Data Network (TOXNET).{{cite journal | vauthors = Fonger GC | title = Hazardous substances data bank (HSDB) as a source of environmental fate information on chemicals | journal = Toxicology | volume = 103 | issue = 2 | pages = 137–45 | year = 1995 | pmid = 8545846 | doi = 10.1016/0300-483x(95)03145-6| bibcode = 1995Toxgy.103..137F | url = https://zenodo.org/record/1258455}} It focused on the toxicology of potentially hazardous chemicals, and included information on human exposure, industrial hygiene, emergency handling procedures, environmental fate, regulatory requirements, and related areas. All data were referenced and derived from a core set of books, government documents, technical reports, and selected primary journal literature. Prior to 2020, all entries were peer-reviewed by a Scientific Review Panel (SRP), members of which represented a spectrum of professions and interests. Last Chairs of the SRP are Dr. Marcel J. Cassavant, MD, Toxicology Group, and Dr. Roland Everett Langford, PhD, Environmental Fate Group. The SRP was terminated due to budget cuts and realignment of the NLM.

The HSDB was organized into individual chemical records, and contained over 5000 such records.{{citation | title = Fact Sheet – Hazardous Substances Data Bank (HSDB) | url = https://www.nlm.nih.gov/pubs/factsheets/hsdbfs.html | publisher = National Library of Medicine | date = September 2006 | access-date = 29 August 2009}} It was accessible free of charge via TOXNET. Users could search by chemical or other name, chemical name fragment, CAS registry number and/or subject terms. Recent additions included radioactive materials and certain mixtures, like crude oil and oil dispersants as well as animal toxins. {{As of|November 2014}}, there were approximately 5,600 chemical specific HSDB records available.{{cite journal | vauthors = Fonger GC, Hakkinen P, Jordan S, Publicker S | title = The National Library of Medicine's (NLM) Hazardous Substances Data Bank (HSDB): background, recent enhancements and future plans | journal = Toxicology | volume = 325 | pages = 209–16 | year = 2014 | pmid = 25223694 | doi = 10.1016/j.tox.2014.09.003 | pmc=4195797| bibcode = 2014Toxgy.325..209F }}