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Heat-responsive protein 12

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

Ribonuclease UK114 is an enzyme that in humans is encoded by the HRSP12 gene.{{cite journal |vauthors=Schmiedeknecht G, Kerkhoff C, Orso E, Stohr J, Aslanidis C, Nagy GM, Knuechel R, Schmitz G | title = Isolation and characterization of a 14.5-kDa trichloroacetic-acid-soluble translational inhibitor protein from human monocytes that is upregulated upon cellular differentiation | journal = Eur J Biochem | volume = 242 | issue = 2 | pages = 339–51 |date=Jan 1997 | pmid = 8973653 | doi =10.1111/j.1432-1033.1996.0339r.x | doi-access = free }}{{cite journal |vauthors=Schmiedeknecht G, Buchler C, Schmitz G | title = A bidirectional promoter connects the p14.5 gene to the gene for RNase P and RNase MRP protein subunit hPOP1 | journal = Biochem Biophys Res Commun | volume = 241 | issue = 1 | pages = 59–67 |date=Jan 1998 | pmid = 9405234 | doi = 10.1006/bbrc.1997.7772 }}{{cite web | title = Entrez Gene: HRSP12 heat-responsive protein 12| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10247}}

References

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Further reading

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  • {{cite journal |vauthors=Mistiniene E, Pozdniakovaite N, Popendikyte V, Naktinis V |title=Structure-based ligand binding sites of protein p14.5, a member of protein family YER057c/YIL051c/YjgF. |journal=Int. J. Biol. Macromol. |volume=37 |issue= 1–2 |pages= 61–8 |year= 2006 |pmid= 16198412 |doi= 10.1016/j.ijbiomac.2005.08.008 }}
  • {{cite journal |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |bibcode=2005Natur.437.1173R |s2cid=4427026 }}
  • {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
  • {{cite journal |vauthors=Manjasetty BA, Delbrück H, Pham DT, etal |title=Crystal structure of Homo sapiens protein hp14.5. |journal=Proteins |volume=54 |issue= 4 |pages= 797–800 |year= 2004 |pmid= 14997576 |doi= 10.1002/prot.10619 |s2cid=723244 |doi-access=free }}
  • {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
  • {{cite journal |vauthors=Kanouchi H, Oka T, Asagi K, etal |title=Expression and cellular distribution of perchloric acid-soluble protein is dependent on the cell-proliferating states of NRK-52E cells. |journal=Cell. Mol. Life Sci. |volume=57 |issue= 7 |pages= 1103–8 |year= 2000 |pmid= 10961346 |doi=10.1007/PL00000746 |s2cid=22844282 |pmc=11146939 }}
  • {{cite journal |vauthors=Morishita R, Kawagoshi A, Sawasaki T, etal |title=Ribonuclease activity of rat liver perchloric acid-soluble protein, a potent inhibitor of protein synthesis. |journal=J. Biol. Chem. |volume=274 |issue= 29 |pages= 20688–92 |year= 1999 |pmid= 10400702 |doi=10.1074/jbc.274.29.20688 |doi-access=free }}
  • {{cite journal |vauthors=Colombo I, Ceciliani F, Ronchi S, etal |title=cDNA cloning and Escherichia coli expression of UK114 tumor antigen. |journal=Biochim. Biophys. Acta |volume=1442 |issue= 1 |pages= 49–59 |year= 1998 |pmid= 9767104 |doi= 10.1016/s0167-4781(98)00120-1}}
  • {{cite journal |vauthors=Racca S, Di Carlo F, Bartorelli A, etal |title=Growth inhibition of DMBA-induced rat mammary carcinomas by UK 114. |journal=Virchows Arch. |volume=431 |issue= 5 |pages= 323–8 |year= 1998 |pmid= 9463573 |doi=10.1007/s004280050106 |s2cid=30926226 }}
  • {{cite journal |vauthors=Oka T, Tsuji H, Noda C, etal |title=Isolation and characterization of a novel perchloric acid-soluble protein inhibiting cell-free protein synthesis. |journal=J. Biol. Chem. |volume=270 |issue= 50 |pages= 30060–7 |year= 1996 |pmid= 8530410 |doi=10.1074/jbc.270.50.30060 |doi-access=free }}

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External links

  • {{UCSC genome browser|HRSP12}}
  • {{UCSC gene details|HRSP12}}

{{PDB Gallery|geneid=10247}}

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