Hepatoprotection
{{Short description|Ability of a chemical substance to prevent liver damage}}
{{Expert needed|medicine|talk=Review by people with mainstream medical expertise needed|reason=Scientific (non-alternative) medicine input needed|date=October 2017}}
Hepatoprotection or antihepatotoxicity is the ability of a chemical substance to prevent damage to the liver. This is opposite to hepatotoxicity.
Hepatoprotective molecules used in emergency medicine
- Acetylcysteine is considered the hepatoprotective drug of choice when treating an overdose of acetaminophen/paracetamol.{{Cite web |url=https://poisoncontrol.utah.edu/newsletters/pdfs/toxicology-today-archive/Vol7_No1.pdf |title=Archived copy |access-date=2019-11-07 |archive-date=2021-06-23 |archive-url=https://web.archive.org/web/20210623190915/https://poisoncontrol.utah.edu/newsletters/pdfs/toxicology-today-archive/Vol7_No1.pdf |url-status=dead }}
- Silymarin is given intravenously to treat poisoning from Amanita mushrooms according to the Santa Cruz protocol devised by Dr Todd Mitchell at UCSC.
Herbs with potentially hepatoprotective constituents
- Astragalus membranaceus{{cite journal|last1=Chien|first1=CF|last2=Wu|first2=YT|last3=Tsai|first3=TH|title=Biological analysis of herbal medicines used for the treatment of liver diseases.|journal=Biomedical Chromatography|date=Jan 2011|volume=25|issue=1–2|pages=21–38|pmid=21204110|doi=10.1002/bmc.1568}}
- Curcuma longa{{cite journal|last1=Ghosh|first1=N|last2=Ghosh|first2=R|last3=Mandal|first3=V|last4=Mandal|first4=SC|title=Recent advances in herbal medicine for treatment of liver diseases.|journal=Pharmaceutical Biology|date=Sep 2011|volume=49|issue=9|pages=970–88|pmid=21595500|doi=10.3109/13880209.2011.558515|doi-access=free}}
- Brassica{{cite journal|last1=Steinkellner|first1=H|last2=Rabot|first2=S|last3=Freywald|first3=C|last4=Nobis|first4=E|last5=Scharf|first5=G|last6=Chabicovsky|first6=M|last7=Knasmüller|first7=S|last8=Kassie|first8=F|title=Effects of cruciferous vegetables and their constituents on drug metabolizing enzymes involved in the bioactivation of DNA-reactive dietary carcinogens.|journal=Mutation Research|date=Sep 1, 2001|volume=480-481|pages=285–97|pmid=11506821|doi=10.1016/S0027-5107(01)00188-9|bibcode=2001MRFMM.480..285S}}
- Silybum marianum, from which silymarin is derived
- Andrographis paniculataAndrographis paniculata http://www.stuartxchange.com/Sinta.html