Hinsberg oxindole synthesis

The Hinsberg oxindole synthesis is a method of preparing oxindoles from the bisulfite additions of glyoxal.{{cite book|author=Elderfield, R.C. |title= Heterocyclic Compounds |volume=3|year=1952|place= New York|page=139}}{{cite journal|last1=Murthy|first1=Sabbavarapu Narayana|last2=Madhav|first2=Bandaru|last3=Nageswar|first3=Yadavalli Venkata Durga|title=Revisiting the Hinsberg Reaction: Facile and Expeditious Synthesis of 3-Substituted Quinoxalin-2(1H)-ones under Catalyst-Free Conditions in Water|journal=Helvetica Chimica Acta|date=15 June 2010|volume=93|issue=6|pages=1216–1220|doi=10.1002/hlca.200900358}} It is named after its inventor Oscar Hinsberg.{{cite journal|author=Hinsberg, O. |journal=Ber. Dtsch. Chem. Ges.|year=1888|volume=21|page= 110|doi=10.1002/cber.18880210122|title=Ueber die Einwirkung der Natriumbisulfitverbindung des Glyoxals auf aromatische Monamine|url=https://zenodo.org/record/1425525}}{{cite journal|last1=Hinsberg|first1=O.|last2=Simeoff|first2=A.|title=Synthese von Naphtindolderivaten|journal=Berichte der Deutschen Chemischen Gesellschaft|date=January 1898|volume=31|issue=1|pages=250–254|doi=10.1002/cber.18980310150|url=https://zenodo.org/record/1425902}}{{cite journal|author=Hinsberg, O. |journal=Ber. Dtsch. Chem. Ges.|year=1908|volume=41|page= 1367|doi=10.1002/cber.190804101252|title=Über Glykokoll und Indol-derivate|url=https://zenodo.org/record/1426277}}

:Image:Hinsbergoxin.png

See also

References