Horace Barker
{{Short description|American biochemist and microbiologist}}
{{Infobox scientist
| birth_name = Horace Albert Barker
| birth_date = {{birth date |1907|11|29}}
| birth_place = Oakland, California, US
| death_date = {{death date and age |2000|12|24 |1907|11|29}}
| death_place = Berkeley, California, US
| fields = Biochemistry
Microbiology
| workplaces = University of California, Berkeley
| alma_mater = Stanford University (B.S., 1929) (Ph.D., 1933)
| thesis_title = The chemistry of egg-albumin with special reference to the phenomenon of heat denaturation
| thesis_url = http://www.worldcat.org/oclc/38721381
| thesis_year = 1933
| doctoral_advisor = James William McBain
| academic_advisors = C. B. van Niel
Albert Kluyver
| awards = National Medal of Science (1968)
| spouse = Margaret McDowell Barker
}}
Horace Albert "Nook" Barker (November 29, 1907 – December 24, 2000) was an American biochemist and microbiologist who studied the operation of biological and chemical processes in plants, humans and other animals, including using radioactive tracers to determine the role enzymes play in synthesizing sucrose. He was recognized with the National Medal of Science for his role in identifying an active form of Vitamin B12.
Early life and education
Barker was born on November 29, 1907, in Oakland, California. He moved with his family to Palo Alto, California when he was 11 years old. He spent a year in Germany following high school, learning the German language and absorbing its culture. He attended Stanford University, graduating in 1929 with a bachelor's degree in physical science, and was awarded a Ph.D. in chemistry in 1933.Ballou, Clinton E. [http://content.cdlib.org/xtf/view?docId=hb987008v1&doc.view=frames&chunk.id=div00004&toc.depth=1&toc.id= "Horace Albert Barker, Biochemistry: Berkeley"], University of California. Accessed July 20, 2009.
After graduating from Stanford, he performed a two-year postgraduate fellowship at the Hopkins Marine Station under the supervision of microbiologist C. B. van Niel, who fostered Barker's interest in botany and taught him techniques for isolating microorganisms. He then spent a year at the Delft Microbiology Laboratory in the Netherlands under Albert Kluyver.
University of California
Barker was hired in 1936 by the University of California, Berkeley to teach soil microbiology. He was part of a team that developed the use of Carbon-14 as a radioactive tracer, using the technique in 1944 to show how sucrose is synthesized in living cells by enzymes.
Research led by Barker during the 1950s provided insights into the uses of vitamin B12 in the body using bacterium he had isolated from mud taken from San Francisco Bay. By 1959, through documenting the metabolic flow of the vitamin B12 coenzyme, Barker was able to show its role in the body, helping to explain various diseases, such as pernicious anemia, one of a series of conditions resulting from vitamin B12 deficiency. In a White House ceremony held on January 17, 1969, U.S. President Lyndon Johnson awarded Barker with the National Medal of Science "[f]or his profound study of the chemical activities of microorganisms, including the unraveling of fatty acid metabolism and the discovery of the active coenzyme form of vitamin B12."[https://www.nsf.gov/od/nms/recip_details.cfm?recip_id=31 The President's National Medal of Science: Recipient Details - H.A. Barker], National Science Foundation. Accessed July 20, 2009.
When the department of biochemistry was established in 1959, he was named as a professor there. He served as the department's chairman in the 1960s, and continued work there for more than a decade after retiring in 1975 when he became an emeritus professor. In 1953, he was elected a member of the United States National Academy of Sciences.{{cite web|title=H. A. Barker|url=http://www.nasonline.org/site/Dir/1905710202?pg=vprof&mbr=1001640|work=National Academy of Sciences|access-date=May 17, 2011}} He was elected a Fellow of the American Academy of Arts and Sciences in 1967.{{cite web|title=Book of Members, 1780-2010: Chapter B|url=http://www.amacad.org/publications/BookofMembers/ChapterB.pdf|publisher=American Academy of Arts and Sciences|access-date=May 17, 2011}}
Personal
A resident of Berkeley, California, Barker died at age 93 on December 24, 2000, due to heart failure at his home there. He had been married for 62 years to his wife, the former Margaret McDowell, at the time of her death in 1995.Saxon, Wolfgang. [https://www.nytimes.com/2001/01/10/us/horace-barker-93-scientist-who-studied-body-chemistry.html "Horace Barker, 93, Scientist Who Studied Body Chemistry"], The New York Times, January 10, 2001. Accessed July 20, 2009.
Eponyms
- Methanosarcina barkeri Schnellen 1947
References
{{Reflist}}
Research resources
- [http://www.oac.cdlib.org/findaid/ark:/13030/hb0t1n991f/ Horace Albert Barker Papers, 1933-1992], The Bancroft Library
External links
- [http://www.nasonline.org/publications/biographical-memoirs/memoir-pdfs/barker-h-a.pdf National Academy of Sciences Biographical Memoir]
{{Winners of the National Medal of Science|biological}}
{{Authority control}}
{{DEFAULTSORT:Barker, Horace}}
Category:20th-century American biochemists
Category:American microbiologists
Category:Fellows of the American Academy of Arts and Sciences
Category:Members of the United States National Academy of Sciences
Category:National Medal of Science laureates
Category:Scientists from Berkeley, California
Category:Scientists from Oakland, California
Category:Stanford University alumni
Category:University of California, Berkeley College of Letters and Science faculty