Howard Green (physician)

{{Infobox scientist

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| name = Howard Green

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| birth_date = {{birth date|1925|9|10}}

| birth_place = Toronto

| death_date = {{death date and age|2015|10|31|1925|9|10}}

| death_place = Boston, Massachusetts

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| workplaces = New York University School of Medicine,
Massachusetts Institute of Technology,
Harvard Medical School

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| alma_mater = University of Toronto

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| known_for = stem-cell research, skin culture

| awards = March of Dimes Prize in Developmental Biology

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| spouse = Rosine Kauffmann

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Howard Green (September 10, 1925 – October 31, 2015) was an American scientist, and George Higginson Professor of Cell Biology at Harvard Medical School.

He was the first to culture human cells in a laboratory setting for therapeutic use. He is one of the founding fathers of stem-cell research and regenerative medicine. One famous case involving Doctor Green concerned Jamie and Glenn Selby, two children from Wyoming who were burned over 95% of their bodies. Green cut small patches of undamaged skin from the boys, grew them in a lab and was able to harvest skin grafts to cover their burns.{{Cite web|title = Howard Green |url = http://www.warrenalpert.org/prize-recipients/howard-green|website = www.warrenalpert.org|accessdate = 2015-10-18}}{{cite news|url=https://www.nytimes.com/2015/11/06/science/howard-green-pioneer-in-skin-regeneration-dies-at-90.html?_r=0|title=Howard Green, Who Found a Way to Grow Skin and Saved Lives, Dies at 90|work=The New York Times|date=November 5, 2015}}

Education and personal life

Howard Green was born in 1925 in Toronto, Ontario. He graduated from University of Toronto medical school.

He served in the United States Army. He taught at New York University School of Medicine, Massachusetts Institute of Technology from 1970 to 1980, and Harvard Medical School from 1980 to 1993.{{Cite news|title = Howard Green, Who Found a Way to Grow Skin and Saved Lives, Dies at 90|url = https://www.nytimes.com/2015/11/06/science/howard-green-pioneer-in-skin-regeneration-dies-at-90.html|newspaper = The New York Times|date = 2015-11-05|access-date = 2015-12-17|issn = 0362-4331|first = Sam|last = Roberts}}

Green married Rosine Kauffmann Green née Kauffmann in 1954.{{Cite web|title = Howard Green dies at 90; Harvard scientist developed technique for regenerating human skin|url = http://www.latimes.com/local/obituaries/la-me-howard-green-20151110-story.html|website = Los Angeles Times|date = 10 November 2015|accessdate = 2015-12-17}}

He died on October 31, 2015, outside Boston, Massachusetts.

On November 23, 2016, Shriner's Hospitals for Children in Boston announced the opening of the Howard Green Center for Children's Skin Health and Research, funded by a $3 million gift from his wife, Mrs. Rosine Kauffmann Green.{{Cite web

| url = http://www.shrinershospitalsforchildren.org/news/~/link.aspx?_id=CC1DCC833F674CFB8115EA4EC4CD786F&_z=z

| title = The Howard Green Center for Children's Skin Health and Research is dedicated to advancing the field of regenerative medicine.

| website = www.shrinershospitalsforchildren.org

| access-date = 2016-02-25

}}{{Cite web

| url = http://www.shrinershospitalsforchildren.org/news/BOS-HowardGreenCenter

| title = Shriners Hospitals for Children

| website = www.shrinershospitalsforchildren.org

| access-date = 2016-02-25

}}

Academic positions held

= [[Harvard Medical School]] =

George Higginson Professor of Cell Biology

Chairman - Department of Cellular and Molecular Physiology 1980-1993

Head of Green Lab

= Massachusetts Institute of Technology =

Professor of Cell Biology{{Cite web|title = Howard Green Department of Pathology|url = http://www.med.nyu.edu/pathology/about/notable-alumni/howard-green|website = www.med.nyu.edu|accessdate = 2015-10-17}}

= [[New York University School of Medicine]] =

Faculty member of the Department of Pathology

Awards and honors

class="wikitable"

!Award

!Year

March of Dimes Prize in Developmental Biology{{Cite web|url = http://www.marchofdimes.org/glue/materials/prize-in-developmental-biology-award-recipient-history.pdf|title = March of Dimes|date = |accessdate = 2015-10-17|website = March of Dimes - Prize Award Recipient History|publisher = March of Dimes|last = |first = }}{{Cite web|title = March of Dimes Awards $250,000 Prize to Two Scientists Who Pioneered Advances in Skin Disorders {{!}} March of Dimes|url = http://www.marchofdimes.org/news/march-of-dimes-awards-250000-prize-to-two-scientists-who-pioneered-advances-in-skin-disorders.aspx|website = www.marchofdimes.org|accessdate = 2015-10-17}}{{Cite web|title = Harvard biologist Dr. Howard Green's $250,000 prize - The Boston Globe|url = https://www.bostonglobe.com/magazine/2012/04/21/harvard-biologist-howard-green-prize/Bg0KGoe686TpxzuGPb3DTI/story.html|website = BostonGlobe.com|accessdate = 2015-10-17}}

|2012

Warren Alpert Foundation Prize{{Cite web|title = Prize Recipients {{!}} warrenalpert.org|url = http://www.warrenalpert.org/prize-recipients|website = www.warrenalpert.org|accessdate = 2015-10-17}}

|2010

Blaise Pascal Award in Medical and Life Sciences of the European Academy of Sciences{{Cite web|title = European Academy of Sciences - Blaise Pascal Medals 2007|url = http://www.eurasc.org/medals/pb_medals_07.asp|website = www.eurasc.org|accessdate = 2015-10-17|archive-url = https://web.archive.org/web/20110119081424/http://www.eurasc.org/medals/pb_medals_07.asp|archive-date = 2011-01-19|url-status = dead}}

|2007

Legion of Honour{{Cite web|title = DR. HOWARD GREEN's Obituary on|url = http://www.legacy.com/obituaries/bostonglobe/obituary.aspx?n=howard-green&pid=176336465&fhid=15232|website = Boston Globe|accessdate = 2015-12-17}}

|2001

Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Research{{Cite web|title = Past Winners {{!}} Rosenstiel Award {{!}} Rosenstiel Basic Medical Sciences Research Center {{!}} Brandeis University|url = http://www.brandeis.edu/rosenstiel/rosenstielaward/past.html|website = www.brandeis.edu|accessdate = 2015-10-18}}

|1979

Selman A. Waksman Award in Microbiology For his fundamental contributions to the biology of cultured animal cells.

|1978

Member, National Academy of Sciences{{Cite web|title = Howard Green|url = http://www.nasonline.org/member-directory/members/20001379.html|website = www.nasonline.org|accessdate = 2015-10-17|url-status = dead|archiveurl = https://web.archive.org/web/20151108170637/http://www.nasonline.org/member-directory/members/20001379.html|archivedate = 2015-11-08}}

|1978

Publications

= Book =

Therapy with Cultured Cells - book published 2010{{Cite book|edition = 1|title = Therapy with Cultured Cells|publisher = Pan Stanford|date = 2010-03-31|location = Singapore|isbn = 9789814267700|first = Howard|last = Green}}

= Selected academic articles =

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!Date

!Title

!Journal

May 1, 1963

|The Growth of Mouse Embryo Cells In Culture and Their Development into Established Lines {{Cite journal|last = Green|first = Howard|title = Quantitative Studies of the Growth of Mouse Embryo Cells in Culture and Their Development into Established Lines|date = May 1, 1963|journal = The Journal of Cell Biology|volume = 17|issue = 2|pages = 299–313|doi = 10.1083/jcb.17.2.299|pmid = 13985244|pmc = 2106200}}

|The Journal of Cell Biology

November 1975

|Serial Cultivation of Strains of Human Epidermal Keratinocytes: The Formation of Keratinzing Colonies from Single Cells{{Cite journal|url = http://rheinwaldlab.bwh.harvard.edu/pdf/Rheinwald,%20Green%201975b,%20Cell,%20Serial.pdf|title = Serial Cultivation of Strains of Human Keratinocytes: the Formation of Keratinizing Colonies from Single Cells|last = Green|first = Howard|date = November 1975|journal = Cell|doi = 10.1016/s0092-8674(75)80001-8|pmid = 1052771|access-date = 2015-10-17|volume=6|issue = 3|pages=331–343|s2cid = 53294766}}

|Cell

November 1979

|Growth of cultured human epidermal cells into multiple epithelia suitable for grafting{{Cite journal|title = Growth of cultured human epidermal cells into multiple epithelia suitable for grafting|last = Green|first = Howard|date = November 1979|journal = Proceedings of the National Academy of Sciences of the United States of America|doi = 10.1073/pnas.76.11.5665|pmid = 293669|volume=76|issue = 11|pages=5665–5668|pmc=411710|bibcode = 1979PNAS...76.5665G|doi-access = free}}

|Proceedings of the National Academy of Sciences of the United States of America

January 10, 1981

|Grafting of Burns with Cultured Epithelium Prepared from Autologous Epidermal Cells{{cite journal|doi=10.1016/S0140-6736(81)90006-4|volume=317|issue = 8211|pages=75–78|journal=The Lancet|date = 1981-01-10|last1 = O'Connor|first1 = Nicholase.|last2 = Mulliken|first2 = Johnb.|last3 = Banks-Schlegel|first3 = Susan|last4 = Kehinde|first4 = Olaniyi|last5 = Green|first5 = Howard|title=Grafting of Burns with Cultured Epithelium Prepared from Autologous Epidermal Cells|s2cid=22718432}}

|The Lancet

References