Hydrocortisone hemisuccinate

{{Short description|Chemical compound}}

{{Drugbox

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| IUPAC_name = 4-[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-Dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoic acid

| image = Hydrocortisone hemisuccinate.svg

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| class = Corticosteroid; Glucocorticoid

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| CAS_number_Ref =

| CAS_number = 2203-97-6

| CAS_supplemental =
110-15-6 (succinic acid)

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| PubChem = 16623

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| DrugBank = DB14545

| ChemSpiderID_Ref =

| ChemSpiderID = 15760

| UNII = IHV1VP592V

| KEGG = D01442

| ChEBI = 31677

| ChEMBL = 977

| synonyms = Hydrocortisone hydrogen succinate; Hydrocortisone succinate; Cortisol 21-hemisuccinate; 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione 21-hemisuccinate

| C=25 | H=34 | O=8

| SMILES = C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)COC(=O)CCC(=O)O)O)C)O

| StdInChI_Ref =

| StdInChI = 1S/C25H34O8/c1-23-9-7-15(26)11-14(23)3-4-16-17-8-10-25(32,24(17,2)12-18(27)22(16)23)19(28)13-33-21(31)6-5-20(29)30/h11,16-18,22,27,32H,3-10,12-13H2,1-2H3,(H,29,30)/t16-,17-,18-,22+,23-,24-,25-/m0/s1

| StdInChIKey_Ref =

| StdInChIKey = VWQWXZAWFPZJDA-CGVGKPPMSA-N

}}

Hydrocortisone hemisuccinate ({{abbrlink|USAN|United States Adopted Name}}), also known as hydrocortisone hydrogen succinate ({{abbrlink|BANM|British Approved Name}}) or simply hydrocortisone succinate and sold under the brand name Solu-Cortel among many others, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester which is used for antiinflammatory and antiallergic indications.{{cite book| vauthors = Elks J |title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA317|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=317–}}{{cite book|title=Index Nominum 2000: International Drug Directory|url=https://books.google.com/books?id=5GpcTQD_L2oC&pg=PA526|year=2000|publisher=Taylor & Francis|isbn=978-3-88763-075-1|pages=526–}}{{cite book| vauthors = Morton IK, Hall JM |title=Concise Dictionary of Pharmacological Agents: Properties and Synonyms|url=https://books.google.com/books?id=tsjrCAAAQBAJ&pg=PA145|date=6 December 2012|publisher=Springer Science & Business Media|isbn=978-94-011-4439-1|pages=145–}}