Hydroxyestrone diacetate
{{Short description|Chemical compound}}
{{Drugbox
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| IUPAC_name = [(8R,9S,13S,14S,16R)-3-acetyloxy-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-16-yl] acetate
| image = Hydroxyestrone diacetate.svg
| width = 250px
| tradename = Colpoginon, Colpormon, Hormobion, Hormocervix
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| routes_of_administration = By mouth
| class = Estrogen; Estrogen ester
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| CAS_number_Ref =
| CAS_number = 1247-71-8
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| PubChem = 102046
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| ChemSpiderID_Ref =
| ChemSpiderID = 92184
| UNII = 2U3VOE52DG
| synonyms = RD-310; 16α-Hydroxyestrone diacetate; 3,16α-Dihydroxyestra-1,3,5(10)-trien-17-one 3,16α-diacetate
| C=22 | H=26 | O=5
| SMILES = CC(=O)OC1CC2C3CCC4=C(C3CCC2(C1=O)C)C=CC(=C4)OC(=O)C
| StdInChI_Ref =
| StdInChI = 1S/C22H26O5/c1-12(23)26-15-5-7-16-14(10-15)4-6-18-17(16)8-9-22(3)19(18)11-20(21(22)25)27-13(2)24/h5,7,10,17-20H,4,6,8-9,11H2,1-3H3/t17-,18-,19+,20-,22+/m1/s1
| StdInChIKey_Ref =
| StdInChIKey = QZQSENRWYLQIPC-JPVHLGFFSA-N
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Hydroxyestrone diacetate (brand names Colpoginon, Colpormon, Hormobion, Hormocervix) (former developmental code name RD-310), or 16α-hydroxyestrone diacetate, also known as 3,16α-dihydroxyestra-1,3,5(10)-trien-17-one 3,16α-diacetate, is a synthetic, steroidal estrogen which has been marketed in France, Spain, Brazil, and Argentina.{{cite book|title=Index Nominum 2000: International Drug Directory|url=https://books.google.com/books?id=5GpcTQD_L2oC&pg=PA531|date=January 2000|publisher=Taylor & Francis|isbn=978-3-88763-075-1|pages=531–}}{{cite book| vauthors = Negwer M, Scharnow HG |title=Organic-chemical drugs and their synonyms: (an international survey)|url=https://books.google.com/books?id=zmpqAAAAMAAJ|year=2001|publisher=Wiley-VCH|isbn=978-3-527-30247-5}} It is a derivative of 16α-hydroxyestrone with an acetate esters attached at the C3 and C16α positions.
See also
References
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{{Estrogens and antiestrogens}}
{{Estrogen receptor modulators}}
{{Steroid-stub}}
{{Genito-urinary-drug-stub}}