IGHG1
{{Short description|Gene in the species Homo sapiens}}
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{{Infobox_gene}}
Ig gamma-1 chain C region is a protein that in humans is encoded by the IGHG1 gene.{{cite web | title = Entrez Gene: IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3500}}
References
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Further reading
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- {{cite journal |vauthors=Ponstingl H, Hilschmann N |title=[The rule of antibody structure. The primary structure of a monoclonal IgG1 immunoglobulin (myeloma protein Nie). III. The chymotryptic peptides of the H-chain, alignment of the tryptic peptides and discussion of the complete structure] |journal=Hoppe-Seyler's Z. Physiol. Chem. |volume=357 |issue= 11 |pages= 1571–604 |year= 1977 |doi=10.1515/bchm2.1976.357.2.1571 |pmid= 826475 }}
- {{cite journal |vauthors=Dreker L, Schwarz J, Reichel W, Hilschmann N |title=[Rule of antibody structure. the primary structure of a monoclonal IgG1 immunoglobulin (myeloma protein Nie), I: Purification and characterization of the protein, the L- and H-chains, the cyanogenbromide cleavage products, and the disulfide bridges (author's transl)] |journal=Hoppe-Seyler's Z. Physiol. Chem. |volume=357 |issue= 11 |pages= 1515–40 |year= 1977 |doi=10.1515/bchm2.1976.357.2.1515 |pmid= 1002129 }}
- {{cite journal |vauthors=Brady RL, Edwards DJ, Hubbard RE, etal |title=Crystal structure of a chimeric Fab' fragment of an antibody binding tumour cells. |journal=J. Mol. Biol. |volume=227 |issue= 1 |pages= 253–64 |year= 1992 |pmid= 1522589 |doi=10.1016/0022-2836(92)90695-G }}
- {{cite journal |vauthors=Gall WE, Edelman GM |title=The covalent structure of a human gamma G-immunoglobulin. X. Intrachain disulfide bonds. |journal=Biochemistry |volume=9 |issue= 16 |pages= 3188–96 |year= 1971 |pmid= 4923144 |doi=10.1021/bi00818a011 }}
- {{cite journal |vauthors=Cunningham BA, Rutishauser U, Gall WE, etal |title=The covalent structure of a human gamma G-immunoglobulin. VII. Amino acid sequence of heavy-chain cyanogen bromide fragments H1-H4. |journal=Biochemistry |volume=9 |issue= 16 |pages= 3161–70 |year= 1971 |pmid= 5489771 |doi=10.1021/bi00818a008 }}
- {{cite journal |vauthors=Rutishauser U, Cunningham BA, Bennett C, etal |title=The covalent structure of a human gamma G-immunoglobulin. 8. Amino acid sequence of heavy-chain cyanogen bromide fragments H5-H7. |journal=Biochemistry |volume=9 |issue= 16 |pages= 3171–81 |year= 1971 |pmid= 5530842 |doi=10.1021/bi00818a009 }}
- {{cite journal |vauthors=Ellison JW, Berson BJ, Hood LE |title=The nucleotide sequence of a human immunoglobulin C gamma1 gene. |journal=Nucleic Acids Res. |volume=10 |issue= 13 |pages= 4071–9 |year= 1982 |pmid= 6287432 |doi=10.1093/nar/10.13.4071 | pmc=320779 }}
- {{cite journal |vauthors=Takahashi N, Ueda S, Obata M, etal |title=Structure of human immunoglobulin gamma genes: implications for evolution of a gene family. |journal=Cell |volume=29 |issue= 2 |pages= 671–9 |year= 1982 |pmid= 6811139 |doi=10.1016/0092-8674(82)90183-0 |s2cid=31733882 |doi-access=free }}
- {{cite journal |vauthors=Schmidt WE, Jung HD, Palm W, Hilschmann N |title=[Three-dimensional structure determination of antibodies. Primary structure of crystallized monoclonal immunoglobulin IgG1 KOL, I] |journal=Hoppe-Seyler's Z. Physiol. Chem. |volume=364 |issue= 6 |pages= 713–47 |year= 1983 |doi=10.1515/bchm2.1983.364.1.713 |pmid= 6884994 }}
- {{cite journal | author=Deisenhofer J |title=Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution. |journal=Biochemistry |volume=20 |issue= 9 |pages= 2361–70 |year= 1981 |pmid= 7236608 |doi=10.1021/bi00512a001 }}
- {{cite journal |vauthors=Paterson T, Innes J, McMillan L, etal |title=Variation in IgG1 heavy chain allotype does not contribute to differences in biological activity of two human anti-Rhesus (D) monoclonal antibodies. |journal=Immunotechnology |volume=4 |issue= 1 |pages= 37–47 |year= 1998 |pmid= 9661813 |doi=10.1016/S1380-2933(98)00005-0 }}
- {{cite journal |vauthors=Masat L, Caldwell J, Armstrong R, etal |title=Association of SWAP-70 with the B cell antigen receptor complex. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 5 |pages= 2180–4 |year= 2000 |pmid= 10681448 |doi= 10.1073/pnas.040374497 | pmc=15774 |bibcode=2000PNAS...97.2180M |doi-access=free }}
- {{cite journal |vauthors=Sondermann P, Huber R, Oosthuizen V, Jacob U |title=The 3.2-A crystal structure of the human IgG1 Fc fragment-Fc gammaRIII complex. |journal=Nature |volume=406 |issue= 6793 |pages= 267–73 |year= 2000 |pmid= 10917521 |doi= 10.1038/35018508 |s2cid=4306592 }}
- {{cite journal |vauthors=Hotta K, Lange H, Tantillo DJ, etal |title=Catalysis of decarboxylation by a preorganized heterogeneous microenvironment: crystal structures of abzyme 21D8. |journal=J. Mol. Biol. |volume=302 |issue= 5 |pages= 1213–25 |year= 2000 |pmid= 11183784 |doi= 10.1006/jmbi.2000.4503 }}
- {{cite journal |vauthors=McLean GR, Nakouzi A, Casadevall A, Green NS |title=Human and murine immunoglobulin expression vector cassettes. |journal=Mol. Immunol. |volume=37 |issue= 14 |pages= 837–45 |year= 2001 |pmid= 11257305 |doi=10.1016/S0161-5890(00)00101-2 }}
- {{cite journal |vauthors=Karpusas M, Lucci J, Ferrant J, etal |title=Structure of CD40 ligand in complex with the Fab fragment of a neutralizing humanized antibody. |journal=Structure |volume=9 |issue= 4 |pages= 321–9 |year= 2001 |pmid= 11525169 |doi=10.1016/S0969-2126(01)00590-1 |doi-access=free }}
- {{cite journal |vauthors=Mimura Y, Sondermann P, Ghirlando R, etal |title=Role of oligosaccharide residues of IgG1-Fc in Fc gamma RIIb binding. |journal=J. Biol. Chem. |volume=276 |issue= 49 |pages= 45539–47 |year= 2002 |pmid= 11567028 |doi= 10.1074/jbc.M107478200 |doi-access= free}}
- {{cite journal |vauthors=Pandey JP, Frederick M |title=TNF-alpha, IL1-beta, and immunoglobulin (GM and KM) gene polymorphisms in sarcoidosis. |journal=Hum. Immunol. |volume=63 |issue= 6 |pages= 485–91 |year= 2002 |pmid= 12039524 |doi=10.1016/S0198-8859(02)00399-3 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
- {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |doi-access= free }}
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