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IL17RC

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

Interleukin-17 receptor C is a protein that in humans is encoded by the IL17RC gene.{{cite journal | vauthors = Haudenschild D, Moseley T, Rose L, Reddi AH | title = Soluble and transmembrane isoforms of novel interleukin-17 receptor-like protein by RNA splicing and expression in prostate cancer | journal = The Journal of Biological Chemistry | volume = 277 | issue = 6 | pages = 4309–16 | date = February 2002 | pmid = 11706037 | doi = 10.1074/jbc.M109372200 | doi-access = free }}{{cite web | title = Entrez Gene: IL17RC interleukin 17 receptor C| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84818}}

Function

This gene encodes a single-pass transmembrane protein that shares limited similarity with the interleukin-17 receptor. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, but the full-length nature of only three have been determined to date.

See also

References

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Further reading

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  • {{cite journal | vauthors = Gerritsen ME, Tomlinson JE, Zlot C, Ziman M, Hwang S | title = Using gene expression profiling to identify the molecular basis of the synergistic actions of hepatocyte growth factor and vascular endothelial growth factor in human endothelial cells | journal = British Journal of Pharmacology | volume = 140 | issue = 4 | pages = 595–610 | date = October 2003 | pmid = 14504135 | pmc = 1574080 | doi = 10.1038/sj.bjp.0705494 }}
  • {{cite journal | vauthors = Zhang Z, Henzel WJ | title = Signal peptide prediction based on analysis of experimentally verified cleavage sites | journal = Protein Science | volume = 13 | issue = 10 | pages = 2819–24 | date = October 2004 | pmid = 15340161 | pmc = 2286551 | doi = 10.1110/ps.04682504 }}
  • {{cite journal | vauthors = Haudenschild DR, Curtiss SB, Moseley TA, Reddi AH | title = Generation of interleukin-17 receptor-like protein (IL-17RL) in prostate by alternative splicing of RNA | journal = The Prostate | volume = 66 | issue = 12 | pages = 1268–74 | date = September 2006 | pmid = 16688746 | doi = 10.1002/pros.20422 | s2cid = 25101473 }}
  • {{cite journal | vauthors = Toy D, Kugler D, Wolfson M, Vanden Bos T, Gurgel J, Derry J, Tocker J, Peschon J | title = Cutting edge: interleukin 17 signals through a heteromeric receptor complex | journal = Journal of Immunology | volume = 177 | issue = 1 | pages = 36–9 | date = July 2006 | pmid = 16785495 | doi = 10.4049/jimmunol.177.1.36 | doi-access = free }}
  • {{cite journal | vauthors = Kuestner RE, Taft DW, Haran A, Brandt CS, Brender T, Lum K, Harder B, Okada S, Ostrander CD, Kreindler JL, Aujla SJ, Reardon B, Moore M, Shea P, Schreckhise R, Bukowski TR, Presnell S, Guerra-Lewis P, Parrish-Novak J, Ellsworth JL, Jaspers S, Lewis KE, Appleby M, Kolls JK, Rixon M, West JW, Gao Z, Levin SD | title = Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F | journal = Journal of Immunology | volume = 179 | issue = 8 | pages = 5462–73 | date = October 2007 | pmid = 17911633 | pmc = 2849293 | doi = 10.4049/jimmunol.179.8.5462 }}

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External links

  • {{MeshName|IL17RC+protein,+human}}

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{{Interleukin receptor modulators}}

Category:IL17 family cytokine receptors

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