INTS12

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

Integrator complex subunit 12 (Int12) also known as PHD finger protein 22 (PHF22) is a protein that in humans is encoded by the INTS12 gene.{{cite web | title = Entrez Gene: integrator complex subunit 12| url = https://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=retrieve&list_uids=57117| accessdate = 2011-08-30}}

INTS12 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1) and U2 (RNU2){{cite journal |vauthors=Baillat D, Hakimi MA, etal |title=Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II. |journal=Cell |volume=123 |issue= 2 |pages= 265–76 |year= 2005 |pmid= 16239144 |doi= 10.1016/j.cell.2005.08.019 |s2cid=18069461 |doi-access=free }}