ITIH3

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

Inter-alpha-trypsin inhibitor heavy chain H3 is a protein that in humans is encoded by the ITIH3 gene.{{cite journal |vauthors=Diarra-Mehrpour M, Bourguignon J, Sesboue R, Mattei MG, Passage E, Salier JP, Martin JP | title = Human plasma inter-alpha-trypsin inhibitor is encoded by four genes on three chromosomes | journal = Eur J Biochem | volume = 179 | issue = 1 | pages = 147–54 |date=Apr 1989 | pmid = 2465147 | doi =10.1111/j.1432-1033.1989.tb14532.x | doi-access = }}{{cite journal |vauthors=Jean L, Risler JL, Nagase T, Coulouarn C, Nomura N, Salier JP | title = The nuclear protein PH5P of the inter-alpha-inhibitor superfamily: a missing link between poly(ADP-ribose)polymerase and the inter-alpha-inhibitor family and a novel actor of DNA repair? | journal = FEBS Lett | volume = 446 | issue = 1 | pages = 6–8 |date=May 1999 | pmid = 10100603 | doi =10.1016/S0014-5793(99)00173-8 | s2cid = 84807160 | doi-access = }}{{cite web | title = Entrez Gene: ITIH3 inter-alpha (globulin) inhibitor H3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3699}}

See also

References

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Further reading

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  • {{cite journal |vauthors=Salier JP, Simon D, Rouet P, etal |title=Homologous chromosomal locations of the four genes for inter-alpha-inhibitor and pre-alpha-inhibitor family in human and mouse: assignment of the ancestral gene for the lipocalin superfamily. |journal=Genomics |volume=14 |issue= 1 |pages= 83–8 |year= 1992 |pmid= 1385302 |doi=10.1016/S0888-7543(05)80287-3 }}
  • {{cite journal |vauthors=Enghild JJ, Salvesen G, Hefta SA, etal |title=Chondroitin 4-sulfate covalently cross-links the chains of the human blood protein pre-alpha-inhibitor. |journal=J. Biol. Chem. |volume=266 |issue= 2 |pages= 747–51 |year= 1991 |doi=10.1016/S0021-9258(17)35235-3 |pmid= 1898736 |doi-access=free }}
  • {{cite journal |vauthors=Salier JP, Diarra-Mehrpour M, Sesboue R, etal |title=Isolation and characterization of cDNAs encoding the heavy chain of human inter-alpha-trypsin inhibitor (I alpha TI): unambiguous evidence for multipolypeptide chain structure of I alpha TI. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=84 |issue= 23 |pages= 8272–6 |year= 1988 |pmid= 2446322 |doi=10.1073/pnas.84.23.8272 | pmc=299524 |doi-access=free }}
  • {{cite journal |vauthors=Enghild JJ, Thøgersen IB, Pizzo SV, Salvesen G |title=Analysis of inter-alpha-trypsin inhibitor and a novel trypsin inhibitor, pre-alpha-trypsin inhibitor, from human plasma. Polypeptide chain stoichiometry and assembly by glycan. |journal=J. Biol. Chem. |volume=264 |issue= 27 |pages= 15975–81 |year= 1989 |doi=10.1016/S0021-9258(18)71575-5 |pmid= 2476436 |doi-access=free }}
  • {{cite journal |vauthors=Diarra-Mehrpour M, Bourguignon J, Sarafan N, etal |title=Tandem orientation of the inter-alpha-trypsin inhibitor heavy chain H1 and H3 genes. |journal=Biochim. Biophys. Acta |volume=1219 |issue= 2 |pages= 551–4 |year= 1994 |pmid= 7522574 |doi= 10.1016/0167-4781(94)90087-6}}
  • {{cite journal |vauthors=Bourguignon J, Diarra-Mehrpour M, Thiberville L, etal |title=Human pre-alpha-trypsin inhibitor-precursor heavy chain. cDNA and deduced amino-acid sequence. |journal=Eur. J. Biochem. |volume=212 |issue= 3 |pages= 771–6 |year= 1993 |pmid= 7681778 |doi=10.1111/j.1432-1033.1993.tb17717.x |doi-access= }}
  • {{cite journal |vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }}
  • {{cite journal |vauthors=Blom AM, Thuveson M, Fries E |title=Intracellular coupling of bikunin and the heavy chain of rat pre-alpha-inhibitor in COS-1 cells |journal=Biochem. J. |volume=328 |issue= 1|pages= 185–91 |year= 1998 |pmid= 9359851 |doi= 10.1042/bj3280185| pmc=1218904 }}
  • {{cite journal |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 }}
  • {{cite journal |vauthors=Diarra-Mehrpour M, Sarafan N, Bourguignon J, etal |title=Human inter-alpha-trypsin inhibitor heavy chain H3 gene. Genomic organization, promoter analysis, and gene linkage |journal=J. Biol. Chem. |volume=273 |issue= 41 |pages= 26809–19 |year= 1998 |pmid= 9756925 |doi=10.1074/jbc.273.41.26809 |doi-access=free }}
  • {{cite journal |vauthors=Thuveson M, Fries E |title=Intracellular proteolytic processing of the heavy chain of rat pre-alpha-inhibitor. The COOH-terminal propeptide is required for coupling to bikunin |journal=J. Biol. Chem. |volume=274 |issue= 10 |pages= 6741–6 |year= 1999 |pmid= 10037773 |doi=10.1074/jbc.274.10.6741 |doi-access=free }}
  • {{cite journal |vauthors=Bourguignon J, Borghi H, Sesboüé R, etal |title=Immunohistochemical distribution of inter-alpha-trypsin inhibitor chains in normal and malignant human lung tissue |journal=J. Histochem. Cytochem. |volume=47 |issue= 12 |pages= 1625–32 |year= 1999 |pmid= 10567446 |doi= 10.1177/002215549904701214|doi-access=free }}
  • {{cite journal |vauthors=Thuveson M, Fries E |title=The low pH in trans-Golgi triggers autocatalytic cleavage of pre-alpha -inhibitor heavy chain precursor |journal=J. Biol. Chem. |volume=275 |issue= 40 |pages= 30996–1000 |year= 2000 |pmid= 10893227 |doi= 10.1074/jbc.M002399200 |doi-access= free }}
  • {{cite journal |vauthors=Kato M, Seki N, Sugano S, etal |title=Identification of sonic hedgehog-responsive genes using cDNA microarray |journal=Biochem. Biophys. Res. Commun. |volume=289 |issue= 2 |pages= 472–8 |year= 2002 |pmid= 11716497 |doi= 10.1006/bbrc.2001.5976 }}
  • {{cite journal |vauthors=Paris S, Sesboüé R, Delpech B, etal |title=Inhibition of tumor growth and metastatic spreading by overexpression of inter-alpha-trypsin inhibitor family chains |journal=Int. J. Cancer |volume=97 |issue= 5 |pages= 615–20 |year= 2002 |pmid= 11807786 |doi=10.1002/ijc.10120 |s2cid=41750371 |doi-access=free }}
  • {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
  • {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |doi-access= free }}

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