Indium (111In) biciromab

{{DISPLAYTITLE:Indium (111In) biciromab}}

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| Verifiedfields = changed

| verifiedrevid = 458273546

| drug_name = Indium (111In) biciromab

| type = mab

| mab_type = Fab'

| source = o

| target = Fibrin II, beta chain

| tradename = FibriScint

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| pregnancy_category = N/A

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| legal_status = Withdrawn

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| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}

| ChemSpiderID = none

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| CAS_number = 138783-13-8

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| KEGG = D03111

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Indium (111In) biciromab (INN, trade name FibriScint, developed by Centocor) was a drug targeting fibrin, a protein involved in the clotting of blood.{{cite journal | vauthors = King DJ, Adair JR | title = Recombinant antibodies for the diagnosis and therapy of human diseases | journal = Current Opinion in Drug Discovery & Development | volume = 2 | issue = 2 | pages = 110–7 | date = March 1999 | pmid = 19649936 }} It was the Fab' fragment of a mouse monoclonal antibody labelled with the radioisotope indium-111 for the diagnosis of thromboembolism,{{cite web | url = http://www.answers.com/topic/centocor-inc | work = Answers.com | title = Centocor Ortho Biotech Products, L.P. }} but was withdrawn during clinical trials.{{cite web | url = https://www.diagnosticimaging.com/view/centocor-withdraws-imaging-agent-applications | work = DiagnosticImaging.com | title = Centocor withdraws imaging agent applications }}

References

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{{Monoclonals for bone, musculoskeletal, circulatory, and neurologic systems}}

Biciromab

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