Indium (111In) biciromab
{{DISPLAYTITLE:Indium (111In) biciromab}}
{{Drugbox
| Verifiedfields = changed
| verifiedrevid = 458273546
| drug_name = Indium (111In) biciromab
| type = mab
| mab_type = Fab'
| source = o
| target = Fibrin II, beta chain
| tradename = FibriScint
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category = N/A
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US =
| legal_status = Withdrawn
| routes_of_administration =
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = none
| CAS_number_Ref = {{cascite|changed|??}}
| CAS_number = 138783-13-8
| ATC_prefix = none
| ATC_suffix =
| PubChem =
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank =
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D03111
| chemical_formula =
| molecular_weight =
}}
Indium (111In) biciromab (INN, trade name FibriScint, developed by Centocor) was a drug targeting fibrin, a protein involved in the clotting of blood.{{cite journal | vauthors = King DJ, Adair JR | title = Recombinant antibodies for the diagnosis and therapy of human diseases | journal = Current Opinion in Drug Discovery & Development | volume = 2 | issue = 2 | pages = 110–7 | date = March 1999 | pmid = 19649936 }} It was the Fab' fragment of a mouse monoclonal antibody labelled with the radioisotope indium-111 for the diagnosis of thromboembolism,{{cite web | url = http://www.answers.com/topic/centocor-inc | work = Answers.com | title = Centocor Ortho Biotech Products, L.P. }} but was withdrawn during clinical trials.{{cite web | url = https://www.diagnosticimaging.com/view/centocor-withdraws-imaging-agent-applications | work = DiagnosticImaging.com | title = Centocor withdraws imaging agent applications }}
References
{{reflist}}
{{Monoclonals for bone, musculoskeletal, circulatory, and neurologic systems}}
{{monoclonal-antibody-stub}}