Infiltrative ophthalmopathy
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Infiltrative ophthalmopathy is found in 5-10% of patients with Graves disease and resembles exophthalmos, except that the blurry or double vision is acquired because of weakness in the ocular muscles of the eye.{{cite book|last1=Munjal|first1=Y. P.|title=API Textbook of Medicine (Volume I & II)|date=2015|publisher=JP Medical Ltd|isbn=9789351524151|page=596|url=https://books.google.com/books?id=z39GCgAAQBAJ&q=Infiltrative+ophthalmopathy|accessdate=5 December 2017|language=en}}{{cite book|last1=McDougall|first1=I. Ross|title=Thyroid Disease in Clinical Practice|date=2013|publisher=Springer|isbn=9781489928818|page=90|url=https://books.google.com/books?id=_nP1BwAAQBAJ&q=Infiltrative+ophthalmopathy|accessdate=5 December 2017|language=en}} In addition, there is no known correlation with the patient's thyroid levels. Exophthalmos associated with Grave's disease disappears when the thyrotoxicosis is corrected. Infiltrative ophthalmopathy at times may not be cured. Treatments consist of high dose glucocorticoids and low dose radiotherapy.{{cite book|last1=Panglossi|first1=Harold V.|title=Antioxidants: New Research|date=2006|publisher=Nova Publishers|isbn=9781594549991|pages=93–95|url=https://books.google.com/books?id=RjtabIeXBlIC&q=Infiltrative+ophthalmopathy|accessdate=5 December 2017|language=en}} The current hypothesis is that infiltrative ophthalmopathy may be autoimmune in nature targeting retrobulbar tissue. Smoking may also have a causative effect.
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Further reading
- {{cite journal | last1=Mallika | first1=Ps | last2=Tan | first2=AK | last3=Aziz | first3=S | last4=Alwi | first4=SAR Syed | last5=Chong | first5=MS | last6=Vanitha | first6=R | last7=Intan | first7=G | title=Thyroid Associated Ophthalmopathy – A Review | journal=Malaysian Family Physician | volume=4 | issue=1 | date=2009 | pages=8–14 | pmid=25606151 | pmc=4170380 | ref=none}}
- {{cite journal | last=Fox | first=Robert A. | title=Infiltrative Ophthalmopathy and Primary Hypothyroidism | journal=Annals of Internal Medicine | volume=67 | issue=2 | date=1967-08-01 | issn=0003-4819 | doi=10.7326/0003-4819-67-2-377 | page=377 | ref=none}}
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