Interleukin-12 receptor

{{Short description|Type I cytokine receptor}}

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{{infobox protein

| Name = interleukin 12 receptor, beta 1

| caption =

| image =

| width =

| HGNCid = 5971

| Symbol = IL12RB1

| AltSymbols = IL12RB, CD212

| EntrezGene = 3594

| OMIM = 601604

| RefSeq = NM_005535

| UniProt = P42701

| PDB =

| ECnumber =

| Chromosome = 19

| Arm = p

| Band = 13.1

| LocusSupplementaryData =

}}

{{infobox protein

| Name = beta 2 subunit, interleukin 12 receptor, beta 2

| caption =

| image =

| width =

| HGNCid = 5972

| Symbol = IL12RB2

| AltSymbols =

| EntrezGene = 3595

| OMIM = 601642

| RefSeq = NM_001559

| UniProt = Q99665

| PDB =

| ECnumber =

| Chromosome = 1

| Arm = p

| Band = 31.3-31.2

| LocusSupplementaryData =

}}

Interleukin 12 receptor is a type I cytokine receptor, binding interleukin 12 and consisting of beta 1{{cite journal |vauthors=Chua AO, Chizzonite R, Desai BB, Truitt TP, Nunes P, Minetti LJ, Warrier RR, Presky DH, Levine JF, Gately MK | title = Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130 | journal = J. Immunol. | volume = 153 | issue = 1 | pages = 128–36 | year = 1994 | doi = 10.4049/jimmunol.153.1.128 | pmid = 7911493 | s2cid = 9211163 | url = http://www.jimmunol.org/cgi/content/abstract/153/1/128 | url-access = subscription }} and beta 2 subunits.{{cite journal |vauthors=Presky DH, Yang H, Minetti LJ, Chua AO, Nabavi N, Wu CY, Gately MK, Gubler U | title = A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 93 | issue = 24 | pages = 14002–14007 | year = 1996 | pmid = 8943050 | doi = 10.1073/pnas.93.24.14002 | pmc = 19484 | bibcode = 1996PNAS...9314002P | doi-access = free }}