International Protein Index
{{short description|Protein database}}
The International Protein Index (IPI) is a defunct protein database launched in 2001 by the European Bioinformatics Institute (EBI), and closed in 2011. Its purpose was to provide the proteomics community with a resource that enables
- accession numbers from a variety of bioinformatics databases to be mapped
- a complete set of proteins for a species i.e. a reference set
In its last version, the IPI contained the complete reference sets for six animal species: Homo sapiens (human), Mus musculus (mouse), Rattus norvegicus (rat), Bos taurus (cattle), Gallus gallus (chicken) and Danio rerio (zebrafish); and one plant species: Arabidopsis thaliana (thale cress). The human, mouse and rat datasets were the first to be developed, combining information taken from the Swiss-Prot, TrEMBL, Ensembl and RefSeq databases.{{cite journal |vauthors=Kersey PJ, Duarte J, Williams A, Karavidopoulou Y, Birney E, Apweiler R |title=The International Protein Index: an integrated database for proteomics experiments |journal=Proteomics |volume=4 |issue=7 |pages=1985–8 |date=July 2004 |pmid=15221759 |doi=10.1002/pmic.200300721 |s2cid=17199787 }}
History
In 2001, when the IPI was launched, databases cataloguing human genes varied greatly and had few links between them. Since then, much more data has been produced giving a more complete picture and databases have collaborated to synchronize data. Currently many model organisms have a reference set of genes/proteins which are catalogued in Ensembl/UniProt respectively, as well as other species specific databases. Because of this redundancy, the IPI was retired in 2011. EBI advised users of its services to employ [https://www.uniprot.org UniProtKB] accession numbers as their protein identifiers.
References
{{Reflist}}
External links
- [http://ftp.ebi.ac.uk/pub/databases/IPI Archive of IPI releases @ EBI]
Category:Databases in the United Kingdom