Intracellular space
{{Short description|Interior space of the plasma membrane}}
{{notability|date=November 2022}}
Intracellular space is the interior space of the plasma membrane.{{cite web|last=|first=|title=Third Spacing: Intracellular Versus Extracellular Space|website=Nurseyourownway.com|publisher=|date=9 May 2020|url=https://nurseyourownway.com/2020/05/10/intracellular-versus-extracellular-space-theres-a-third-space/|access-date=15 November 2022|archive-date=15 November 2022|archive-url=https://web.archive.org/web/20221115091722/https://nurseyourownway.com/2020/05/10/intracellular-versus-extracellular-space-theres-a-third-space/|url-status=dead}}{{cite web|last=|first=|title=What Are Intracellular Structures?|website=Study.com|publisher=|date=|url=https://study.com/academy/lesson/intracellular-definition-structures-quiz.html|access-date=15 November 2022}} It contains about two-thirds of TBW. Cellular rupture may occur if the intracellular space becomes dehydrated, or if the opposite happens, where it becomes too bloated. Thus it is important for the liquid to stay in optimal quantity.