Iratumumab
{{Short description|Monoclonal antibody}}
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| type = mab
| mab_type = mab
| source = u
| target = CD30
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| CAS_number = 640735-09-7
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = AYH22O1B1U
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| KEGG = D04612
| C=6358 | H=9830 | N=1682 | O=1992 | S=38
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Iratumumab is a human monoclonal antibody that was investigated for treating oncological diseases such as relapsed refractory CD30-positive lymphoma including Hodgkin's disease.{{cite web | title = Statement On A Nonproprietary Name Adopted By The USAN Council – Iratumumab | url = http://www.ama-assn.org/ama1/pub/upload/mm/365/iratumumab.doc | archive-url = https://web.archive.org/web/20110604015047/http://www.ama-assn.org/ama1/pub/upload/mm/365/iratumumab.doc | archive-date = 4 June 2011| publisher = American Medical Association }}{{cite journal | vauthors = Fanale MA, Younes A | title = Monoclonal antibodies in the treatment of non-Hodgkin's lymphoma | journal = Drugs | volume = 67 | issue = 3 | pages = 333–350 | date = 2007 | pmid = 17335294 | doi = 10.2165/00003495-200767030-00002 }}
This drug was developed by Medarex, which was later acquired by Bristol-Myers Squibb.
The FDA granted orphan drug designation for Hodgkin's lymphoma in 2004. In 2009, development was suspended with no explanation given.{{cite web | title = Iratumumab | url = http://adisinsight.springer.com/drugs/800017758 | website = AdisInsight | access-date = 30 January 2017 }}
References
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{{Monoclonals for tumors}}
Category:Monoclonal antibodies for tumors
Category:Experimental cancer drugs
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