Isoliquiritigenin 2'-O-methyltransferase

{{infobox enzyme

| Name = Isoliquiritigenin 2'-O-methyltransferase

| EC_number = 2.1.1.154

| CAS_number = 139317-14-9

| GO_code =

| image =

| width =

| caption =

}}

In enzymology, an isoliquiritigenin 2'-O-methyltransferase ({{EC number|2.1.1.154}}) is an enzyme that catalyzes the chemical reaction

:S-adenosyl-L-methionine + isoliquiritigenin $\rightleftharpoons$ S-adenosyl-L-homocysteine + 2'-O-methylisoliquiritigenin

Thus, the two substrates of this enzyme are S-adenosyl methionine and isoliquiritigenin, whereas its two products are S-adenosylhomocysteine and 2'-O-methylisoliquiritigenin.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:isoliquiritigenin 2'-O-methyltransferase. Other names in common use include chalcone OMT, and CHMT.

References

{{cite journal | vauthors = Maxwell CA, Edwards R, Dixon RA | date = 1992 | title = Identification, purification, and characterization of S-adenosyl-L-methionine: isoliquiritigenin 2'-O-methyltransferase from alfalfa (Medicago sativa L.) | journal = Arch. Biochem. Biophys. | volume = 293 | pages = 158–66 | pmid = 1731632 | doi = 10.1016/0003-9861(92)90379-B | issue = 1 }}
{{cite journal | vauthors = Ichimura M, Furuno T, Takahashi T, Dixon RA, Ayabe S | date = 1997 | title = Enzymic O-methylation of isoliquiritigenin and licodione in alfalfa and licorice cultures | journal = Phytochemistry | volume = 44 | pages = 991–5 | pmid = 9055445 | doi = 10.1016/S0031-9422(96)00670-X | issue = 6 }}

Category:EC 2.1.1

Category:Enzymes of unknown structure

Category:Chalconoids metabolism