Its

ITS, its or it's may refer to:

Language

It's, an English contraction of it is or it has
Its (pronoun), the possessive form of the pronoun it
Itsekiri language (ISO 639 language code its), a language found in Nigeria and the Niger Delta

Illinois Traction System, an American railroad
Industrial Tomography Systems, a manufacturer of process visualization systems based upon the principles of tomography
International Transportation Service, an American container terminal company

Indian Theological Seminary, an interdenominational seminary in India
Sepuluh Nopember Institute of Technology (Institut Teknologi Sepuluh Nopember), a public engineering institute in Surabaya, Indonesia
Institute for Transport Studies, University of Leeds (ITS Leeds)
Institute of Technological Studies, Sri Lanka
Institute of Technology, Sligo, Ireland
Institute of Transportation Studies, University of California Berkeley, Davis, Irvine and Los Angeles

Identity, Tradition, Sovereignty, a former political grouping in the European Parliament
Indian Telecommunication Service, an organised civil service of Government of India
Indian Trade Service
International Thespian Society, an honorary organization for high school and middle school theatre students
International Tracing Service
International trade secretariat
International Typographers' Secretariat, a former international trade secretariat
Irish Texts Society, promoting the study of literature
Irish Thoracic Society
Islamic Texts Society, an educational charity based in Cambridge, UK
Islamic Thinkers Society
Individualists Tending to the Wild ({{lang|es|Individualistas Tendiendo a lo Salvaje}}), an eco-extremist terrorist group in Mexico

Incompatible Timesharing System, a computer operating system
Intelligent tutoring system, an artificial intelligence system used for tutoring
Internationalization Tag Set, a W3C recommendation for internationalizing XML
Issue tracking system, computer software that manages product issues

Inverse transform sampling, a method for generating random numbers from various probability distribution
Internal transcribed spacer, a section of DNA located within a set of ribosomal genes
Interrupted time series, a time series of data known to be affected by interventions

ITS, a ship prefix associated with the Marina Militare, the Italian Navy of the Republic of Italy
Intelligent transportation system, transportation infrastructure information technology
Interplanetary Transport System, a project by SpaceX to develop a system capable of transporting humans and cargo to Mars and other destinations in space
Inter-State Aviation (ICAO airline code ITS), U.S. airline; see List of airline codes (I)