Jacques Fellay

Fellay studied medicine in Fribourg, Lausanne and Vienna, and obtained his medical degree from the University of Lausanne in 2000. He then received an MD from the University of Lausanne and a PhD from Utrecht University. He was clinically trained in infectious diseases in Switzerland, before spending 4 years as a research scientist at Duke University. He joined the School of Life Sciences, EPFL in 2011.

Fellay is associate Professor in the School of Life Sciences, EPFL and at the University of Lausanne, founding director of the Precision Medicine Unit of the Lausanne University Hospital, group leader at the Swiss Institute of Bioinformatics, as well as co-director of the Health2030 Genome Center in Geneva.{{Cite web|title=Unité de médecine de précision du CHUV - Équipe|url=https://www.chuv.ch/fr/medecine-precision/accueil/en-bref/notre-equipe/|access-date=1 September 2020|website=chuv.ch|language=fr}}{{Cite web|title=Jacques Fellay's group at the SIB|url=https://www.sib.swiss/jacques-fellay-group|access-date=1 September 2020|website=sib.swiss}}{{Cite web|title=For the public – Health2030 – Genome Center|url=https://www.health2030genome.ch/for-the-public/|access-date=1 September 2020|language=fr-FR}}

He is a member of the Swiss Federal Commission for Genetic Studies in Humans{{Cite web|last=BAG|first=Bundesamt für Gesundheit|title=Eidgenössische Kommission für genetische Untersuchungen beim Menschen (GUMEK)|url=https://www.bag.admin.ch/bag/de/home/das-bag/organisation/ausserparlamentarische-kommissionen/expertenkommission-fuer-genetische-untersuchungen-beim-menschen.html|access-date=1 September 2020|website=www.bag.admin.ch|language=de}} and of the Swiss National COVID-19 Science Task Force.{{Cite web|title=ncs-tf.ch: Topics & Expert groups|url=https://ncs-tf.ch/en/topics-expert-groups|access-date=1 September 2020|website=ncs-tf.ch}}

Fellay leads the laboratory of Human Genomics of Infection and Immunity at EPFL, which uses large-scale genomic approaches and bioinformatic tools to explore the impact of human genetic variation on infectious diseases, immune parameters and host-pathogen interactions. At the crossroad between basic biomedical science and the clinical world, his research aims at identifying the genomic factors modulating the human response to infectious and immune diseases, with the ultimate goal of offering novel diagnostic, preventative or therapeutic solutions customized to the unique genetic background of every patient.{{Cite web|title=Fellay Lab – Human Genomics of Infection and Immunity|url=https://www.epfl.ch/labs/fellay-lab/|access-date=1 September 2020|website=www.epfl.ch|language=en-GB}} His publications have led to the identification of genetic factors influencing host control and therapy response to viral infections such as HIV, Hepatitis C or respiratory diseases.{{Cite journal|last1=Ge|first1=Dongliang|last2=Fellay|first2=Jacques|last3=Thompson|first3=Alexander J.|last4=Simon|first4=Jason S.|last5=Shianna|first5=Kevin V.|last6=Urban|first6=Thomas J.|last7=Heinzen|first7=Erin L.|last8=Qiu|first8=Ping|last9=Bertelsen|first9=Arthur H.|last10=Muir|first10=Andrew J.|last11=Sulkowski|first11=Mark|date=September 2009|title=Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance|url=https://www.nature.com/articles/nature08309|journal=Nature|language=en|volume=461|issue=7262|pages=399–401|doi=10.1038/nature08309|pmid=19684573|bibcode=2009Natur.461..399G|s2cid=1707096|issn=1476-4687}}{{Cite journal|last1=Fellay|first1=Jacques|last2=Shianna|first2=Kevin V.|last3=Ge|first3=Dongliang|last4=Colombo|first4=Sara|last5=Ledergerber|first5=Bruno|last6=Weale|first6=Mike|last7=Zhang|first7=Kunlin|last8=Gumbs|first8=Curtis|last9=Castagna|first9=Antonella|last10=Cossarizza|first10=Andrea|last11=Cozzi-Lepri|first11=Alessandro|date=17 August 2007|title=A Whole-Genome Association Study of Major Determinants for Host Control of HIV-1|journal=Science|language=en|volume=317|issue=5840|pages=944–947|doi=10.1126/science.1143767|issn=0036-8075|pmid=17641165|pmc=1991296|bibcode=2007Sci...317..944F}}{{Cite journal|last1=Fellay|first1=Jacques|last2=Thompson|first2=Alexander J.|last3=Ge|first3=Dongliang|last4=Gumbs|first4=Curtis E.|last5=Urban|first5=Thomas J.|last6=Shianna|first6=Kevin V.|last7=Little|first7=Latasha D.|last8=Qiu|first8=Ping|last9=Bertelsen|first9=Arthur H.|last10=Watson|first10=Mark|last11=Warner|first11=Amelia|date=March 2010|title=ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C|url=https://www.nature.com/articles/nature08825|journal=Nature|language=en|volume=464|issue=7287|pages=405–408|doi=10.1038/nature08825|pmid=20173735|bibcode=2010Natur.464..405F|s2cid=205219827|issn=1476-4687}}{{Cite journal|last1=McLaren|first1=Paul J.|last2=Coulonges|first2=Cedric|last3=Bartha|first3=István|last4=Lenz|first4=Tobias L.|last5=Deutsch|first5=Aaron J.|last6=Bashirova|first6=Arman|last7=Buchbinder|first7=Susan|last8=Carrington|first8=Mary N.|last9=Cossarizza|first9=Andrea|last10=Dalmau|first10=Judith|last11=Luca|first11=Andrea De|date=24 November 2015|title=Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load|journal=Proceedings of the National Academy of Sciences|language=en|volume=112|issue=47|pages=14658–14663|doi=10.1073/pnas.1514867112|issn=0027-8424|pmid=26553974|pmc=4664299|bibcode=2015PNAS..11214658M|doi-access=free}}{{Cite web|title=Research effort reveals gene variants that play a role in HIV viral load in patients|url=https://medicalxpress.com/news/2015-11-effort-reveals-gene-variants-role.html|access-date=1 September 2020|website=medicalxpress.com|language=en}}{{Cite journal|date=5 November 2015|title=Amino Acid Variation in HLA Class II Proteins Is a Major Determinant of Humoral Response to Common Viruses|url= |journal=The American Journal of Human Genetics|language=en|volume=97|issue=5|pages=738–743|doi=10.1016/j.ajhg.2015.09.008|issn=0002-9297|last1=Hammer|first1=Christian|last2=Begemann|first2=Martin|last3=McLaren|first3=Paul J.|last4=Bartha|first4=István|last5=Michel|first5=Angelika|last6=Klose|first6=Beate|last7=Schmitt|first7=Corinna|last8=Waterboer|first8=Tim|last9=Pawlita|first9=Michael|last10=Schulz|first10=Thomas F.|last11=Ehrenreich|first11=Hannelore|last12=Fellay|first12=Jacques|pmid=26456283|pmc=4667104}}{{Cite web|last=Goldsobel|first=Gady|date=12 October 2015|title=Genetic variation is key to fighting viruses|url=http://www.healthcanal.com/genetics-birth-defects/67722-genetic-variation-is-key-to-fighting-viruses.html|access-date=1 September 2020|website=Healthcanal.com|language=en-US}}{{Cite journal|last1=Asgari|first1=Samira|last2=Schlapbach|first2=Luregn J.|last3=Anchisi|first3=Stéphanie|last4=Hammer|first4=Christian|last5=Bartha|first5=Istvan|last6=Junier|first6=Thomas|last7=Mottet-Osman|first7=Geneviève|last8=Posfay-Barbe|first8=Klara M.|last9=Longchamp|first9=David|last10=Stocker|first10=Martin|last11=Cordey|first11=Samuel|date=1 August 2017|title=Severe viral respiratory infections in children with IFIH1 loss-of-function mutations|journal=Proceedings of the National Academy of Sciences|language=en|volume=114|issue=31|pages=8342–8347|doi=10.1073/pnas.1704259114|issn=0027-8424|pmid=28716935|pmc=5547624|doi-access=free}}{{Cite news|date=18 July 2017|title=A gene increases the severity of common colds|language=en|url=http://www.snf.ch/en/researchinFocus/newsroom/Pages/news-170718-press-release-a-gene-increases-the-severity-of-common-colds.aspx#|access-date=1 September 2020}}

Fellay was awarded with the 2012 National Latsis Prize and the 2015 Leenaards Prize for translational medical research for his contributions to the better understanding of genetic susceptibility to HIV and Hepatitis C infections.{{Cite news|date=13 January 2013|title=Jacques Fellay voudrait mieux connaître les vaches de ses patients|language=fr|work=Le Temps|url=https://www.letemps.ch/sciences/jacques-fellay-voudrait-mieux-connaitre-vaches-patients|access-date=1 September 2020|issn=1423-3967}}{{Cite web|title=Jacques Fellay receives the National Latsis Prize 2012 - SNF|url=http://www.snf.ch/en/researchinFocus/newsroom/Pages/news-130107-press-release-jacques-fellay-receives-national-latsis-prize.aspx|access-date=1 September 2020|website=www.snf.ch}}{{Cite journal|last=Daugey|first=Fleur|date=December 2012|title=Un chercheur qui a les pieds sur terre|url=https://scienzenaturali.ch/uuid/09cedf74-1d4a-5aba-8bf6-f2c6dac1a23c?r=20170706115333_1499301306_359ff08e-74a1-565a-9e14-2caa1d141f97|journal=Horizons|language=fr|pages=18–19}}{{Cite web|title=Génome contre génome : l'impact des variations génétiques humaines sur les infections virales chroniques|url=https://www.leenaards.ch/prix/genome-contre-genome-limpact-des-variations-genetiques-humaines-sur-les-infections-virales-chroniques/|access-date=1 September 2020|website=Fondation Leenaards - Favoriser la dynamique créatrice|language=fr}}{{Cite web|title=Corpus - Radio|url=https://www.rts.ch/play/radio/corpus/audio/corpus?id=6625260|access-date=1 September 2020|website=Play RTS|date = 24 March 2015|language=fr}}

He also received the Basic Research in Infectious Diseases Award in 2008 and 2017 from the Swiss Society for Infectious Diseases.{{Cite web|title=Awards & Fellows – Swiss Society for Infectious Diseases|url=https://www.sginf.ch/about-us/awards-und-fellows/awards-und-fellows.html|access-date=1 September 2020|website=www.sginf.ch}}

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Category:Academic staff of the École Polytechnique Fédérale de Lausanne

Category:1974 births

Category:Living people

Category:Swiss medical researchers

Category:Academic staff of the University of Lausanne

{{DEFAULTSORT:Fellay, Jacques}}