Jane Armitage
{{Short description|British academic}}
{{Infobox scientist
| birth_name = Jane Margaret Armitage
| honorific_suffix = {{Post-nominals|country=GBR|OBE|FRCP|FFPH|size=100}}
| name = Jane Armitage
| workplaces = University of Oxford
Clinical Trial Service Unit
| fields = Cardiovascular disease
Clinical trials
| website = {{URL|https://www.ndph.ox.ac.uk/team/jane-armitage}}
}}
Jane Margaret Armitage is a professor of clinical trials and epidemiology in the Clinical Trial Service Unit at the University of Oxford. She works on the epidemiology of cardiovascular disease and has led large-scale randomized controlled trials.
Early life and education
Armitage qualified in medicine in 1979.{{Cite book|url=https://books.google.com/books?id=JIUqBgAAQBAJ&q=jane+armitage+1979&pg=PA196|title=The Medical Directory 2015|last=Wren|first=Brenda|date=2014-12-16|publisher=CRC Press|isbn=9781498728393|location=|pages=196|language=en}} She worked in respiratory medicine, geriatrics and diabetes.{{Cite web|url=https://www.hpsinfo.org/biog_ja.shtml|title=HPS Info : Biography : Jane Armitage|website=www.hpsinfo.org|access-date=2019-06-19}}
Research and career
In 1990 Armitage joined the Clinical Trial Service Unit.{{Cite web|url=https://www.ndph.ox.ac.uk/team/jane-armitage|title=Jane Armitage—Nuffield Department of Population Health|website=www.ndph.ox.ac.uk|access-date=2019-06-19}} She has served as Director of Training & Career Development as well as leading the Medical Research Council Population Health Research Unit.{{Cite web|url=https://www.ctsu.ox.ac.uk/news/professor-jane-armitage-recognised-for-services-to-medical-research|title=Professor Jane Armitage recognised for services to medical research—Oxford Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU)|website=www.ctsu.ox.ac.uk|access-date=2019-06-19}} She is best known for her work on the safety of statins.{{Cite journal|last=Armitage|first=Jane|date=2007-11-24|title=The safety of statins in clinical practice|url=https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(07)60716-8/abstract|journal=The Lancet|language=English|volume=370|issue=9601|pages=1781–1790|doi=10.1016/S0140-6736(07)60716-8|issn=0140-6736|pmid=17559928|s2cid=205948651}}
Armitage led the 1999 Medical Research Council and British Heart Foundation Heart Protection Study, which included 20,000 participants.{{Cite web|url=http://www.ox.ac.uk/news-and-events/find-an-expert/professor-jane-armitage|title=Professor Jane Armitage {{!}} University of Oxford|website=www.ox.ac.uk|access-date=2019-06-19}} The study is the largest that investigates the use of statins to prevent cardiovascular disease. She was also the lead for the Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine (SEARCH) study and the Heart Protection Study 2 (HPS2) Treatment of HDL to Reduce the Incidence of Vascular Events (THRIVE) study.{{Cite web|url=https://www.thrivestudy.org/|title=THRIVE Home Page|website=www.thrivestudy.org|access-date=2019-06-19}} She demonstrated that statins are also safe for patients with rheumatoid arthritis.{{Cite web|url=https://www.sciencedaily.com/releases/2019/04/190415122259.htm|title=Statins safe for preventing cardiovascular events in rheumatoid arthritis patients, study suggests|website=ScienceDaily|language=en|access-date=2019-06-20}}
Armitage was Chief Investigator for the ASCEND aspirin trial, which studied cardiovascular disease in 15,480 patients with diabetes.{{Cite web|url=https://castbox.fm/episode/ACCEL-Lite%3A-Featured-ACCEL-Interview-With-Erik-Magnus-Ohman-and-Jane-Margaret-Armitage-id1087024-id109492446|title=ACCEL Lite: Featured ACCEL Interview With Erik Magnus Ohman and Jane Margaret Armitage|website=castbox.fm|language=en|access-date=2019-06-19}}{{Cite web|url=https://www.mdmag.com/medical-news/qa-jane-armitage-frcp-ffph-on-the-ascend-trial-results-for-aspirin-benefits|title=Q&A: Jane Armitage, FRCP, FFPH, on the ASCEND Trial Results for Aspirin Benefits|website=MD Magazine|access-date=2019-06-19}} ASCEND was the largest ever study that had every been performed to investigate whether aspirin should be used to prevent cardiovascular disease in diabetic patients. The trial found that whilst aspirin reduces the risk of cardiovascular events by 12%, it increases the risk of major bleeding.{{Cite web|url=http://www.medscape.com/viewarticle/901212|title=ASCEND: Aspirin Not Needed for Primary Prevention in Diabetes|website=Medscape|access-date=2019-06-19}} As an addition to the ASCEND study, Armitage was supported by Alzheimer's Research UK to study the impact of aspirin and fish oil on memory and cognition in patients with diabetes and Alzheimer's disease.{{Cite web|url=https://www.alzheimersresearchuk.org/oxford-researchers-ask-whether-fish-oils-aspirin-delay-dementia/|title=Oxford researchers to ask whether fish oils or aspirin could delay dementia|date=2016-09-21|website=Alzheimer's Research UK|language=en-GB|access-date=2019-06-20|archive-date=2019-06-20|archive-url=https://web.archive.org/web/20190620020606/https://www.alzheimersresearchuk.org/oxford-researchers-ask-whether-fish-oils-aspirin-delay-dementia/|url-status=dead}} They also studied whether aspirin changes the risk of developing dementia and Alzheimer's disease. She also investigated whether fish oil and vitamin D supplements reduced cardiovascular disease in diabetic patients, but found they had no impact.{{Cite web|url=https://www.modernhealthcare.com/article/20181112/NEWS/181119995/heart-meeting-features-fish-oil-vitamin-d-cholesterol-news|title=Heart meeting features fish oil, vitamin D, cholesterol news|date=2018-11-12|website=Modern Healthcare|language=en|access-date=2019-06-20}}
She is an editor for the journal Atherosclerosis.{{Cite web|url=https://www.eas-society.org/page/armitage|title=Jane Armitage - European Atherosclerosis Society|website=www.eas-society.org|access-date=2019-06-19}}
= Awards and honours =
2019 Awarded an Officer of the Order of the British Empire for services to medical research{{Cite web|url=http://www.ox.ac.uk/news/2018-12-29-new-years-honours-2019|title=New Year's Honours 2019 {{!}} University of Oxford|website=www.ox.ac.uk|date=29 December 2018 |language=en|access-date=2019-06-18}}
References
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{{DEFAULTSORT:Armitage, Jane}}
Category:British women medical doctors
Category:Academics of the University of Oxford
Category:Officers of the Order of the British Empire
Category:British women epidemiologists
Category:British epidemiologists