Jason Wallach

{{Short description|American pharmacologist}}

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| birth_date = {{Birth year and age|1987}}

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| alma_mater = Indiana University of Pennsylvania; University of the Sciences

| occupation = Pharmacologist; Assistant professor

| years_active = 2009–present{{cite journal | vauthors = Wallach JV | title = Endogenous hallucinogens as ligands of the trace amine receptors: a possible role in sensory perception | journal = Med Hypotheses | volume = 72 | issue = 1 | pages = 91–4 | date = January 2009 | pmid = 18805646 | doi = 10.1016/j.mehy.2008.07.052 | url = }}{{cite journal | vauthors = Morris H, Wallach J | title = From PCP to MXE: a comprehensive review of the non-medical use of dissociative drugs | journal = Drug Test Anal | volume = 6 | issue = 7-8 | pages = 614–632 | date = 2014 | pmid = 24678061 | doi = 10.1002/dta.1620 | url = }}

| employer = Saint Joseph's University; Philadelphia College of Pharmacy

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| website = https://directory.sju.edu/jason-wallach
https://www.wallachlab.com/

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Jason Wallach (born 1987) is an American pharmacologist who studies psychedelic drugs and other hallucinogens.{{cite web | last=Semley | first=John | title=The High-Stakes Race to Engineer New Psychedelic Drugs | website=WIRED | date=26 July 2022 | url=https://www.wired.com/story/race-to-engineer-new-psychedelic-drugs/ | access-date=28 January 2025 | archive-url = https://archive.today/20241226123831/https://www.wired.com/story/race-to-engineer-new-psychedelic-drugs/ | archive-date = 26 December 2024 }}{{cite web | author=Ben Seal | title=A Psychedelic Renaissance | date = May 2024 | website=Saint Joseph's University Magazine | url=https://www.sju.edu/news/magazine/psychedelic-renaissance | access-date=28 January 2025}}{{cite web | last=Wood | first=Sam | title=Envisioning a psychedelic future for Philadelphia’s USciences as it pairs with Compass Pathways for a Drug Discovery Center | website=inquirer.com | date=15 February 2021 | url=https://www.inquirer.com/business/drugs/psychedelics-compass-pathways-wallach-university-of-the-sciences-usciences-20210215.html | access-date=28 January 2025 | archive-url = https://archive.today/20210215145316/https://www.inquirer.com/business/drugs/psychedelics-compass-pathways-wallach-university-of-the-sciences-usciences-20210215.html | archive-date = 15 February 2021 }} He is an assistant professor at Saint Joseph's University's Philadelphia College of Pharmacy.

In August 2020, Wallach began a partnership with the pharmaceutical company Compass Pathways for his research lab to develop novel psychedelic drugs as therapeutics.{{cite web | title=Psychedelic Compounds are Focus of USciences Lab | website=Newsroom | date=18 October 2021 | url=https://www.sju.edu/news/psychedelic-compounds-are-focus-usciences-lab | access-date=9 January 2025}} Hamilton Morris, a psychedelic journalist and the host of Hamilton's Pharmacopeia, works as a chemist in Wallach's lab.

Wallach graduated from Indiana University of Pennsylvania with his bachelor's degree in cell and molecular biology in 2008 and graduated with his Doctor of Philosophy degree in pharmacology and toxicology from the University of the Sciences in 2014.{{cite web | title=Jason V Wallach | website=University Directory | url=https://directory.sju.edu/jason-wallach | access-date=28 January 2025}}

In 2023, Wallach, Morris, and other colleagues published a key paper characterizing the serotonin 5-HT_2A receptor intracellular signaling cascades mediating the head-twitch response, a behavioral proxy of psychedelic effects, in rodents.{{cite web | last=Lomte | first=Tarun Sai | title=Scientists design non-hallucinogenic psychedelic treatments potentially accelerating research on mental health benefits | website=News-Medical | date=19 December 2023 | url=https://www.news-medical.net/news/20231219/Scientists-design-non-hallucinogenic-psychedelic-treatments-potentially-accelerating-research-on-mental-health-benefits.aspx | access-date=28 January 2025}}{{cite web | title=Trip or treat? | website=EurekAlert! | date=15 December 2023 | url=https://www.eurekalert.org/news-releases/1010979 | access-date=28 January 2025}}{{cite journal | vauthors = Wallach J, Cao AB, Calkins MM, Heim AJ, Lanham JK, Bonniwell EM, Hennessey JJ, Bock HA, Anderson EI, Sherwood AM, Morris H, de Klein R, Klein AK, Cuccurazzu B, Gamrat J, Fannana T, Zauhar R, Halberstadt AL, McCorvy JD | title = Identification of 5-HT2A receptor signaling pathways associated with psychedelic potential | journal = Nat Commun | volume = 14 | issue = 1 | pages = 8221 | date = December 2023 | pmid = 38102107 | pmc = 10724237 | doi = 10.1038/s41467-023-44016-1 | url = }}