Jenner Institute

{{Short description|Vaccine research institute in Oxford}}

{{Use dmy dates|date=November 2020}}

{{Use British English|date=November 2020}}

{{Infobox institute

| image = Jenner_Institute_Logo.png

| established = {{start date and age|2005|11}}

| head_label = Director

| head = Adrian Hill

| key_people = Sarah Gilbert
Helen McShane

| parent = University of Oxford

| budget =

| remarks =

| name = The Jenner Institute

| location = Old Road Campus Research Building

| address = Old Road Campus Research Building (ORCRB), Roosevelt Drive, Oxford OX3 7DQ, UK

| city = Oxford

| country = United Kingdom

| staff = 100

| website = {{Official URL}}

| former_name = Edward Jenner Institute for Vaccine Research

| coordinates = {{coord|51.7519293|-1.2163045|dim:500_region:GB-OXF_type:landmark|display=inline,title}}

}}

The Jenner Institute is a research institute on the Old Road Campus in Headington, east Oxford, England. It was formed in November 2005 through a partnership between the University of Oxford and the UK Institute for Animal Health.{{cite web | url=https://www.ndm.ox.ac.uk/the-jenner-institute | title=The Jenner Institute | work=Health Check | publisher=Nuffield Department of Medicine, University of Oxford | location=UK | access-date=17 April 2020 | archive-date=27 May 2020 | archive-url=https://web.archive.org/web/20200527013440/https://www.ndm.ox.ac.uk/the-jenner-institute | url-status=dead }} It is associated with the Nuffield Department of Medicine, in the Medical Sciences Division of Oxford University. The institute receives charitable support from the Jenner Vaccine Foundation.{{Twitter|JennerInstitute}}

The institute is led by Prof. Adrian Hill.{{cite web| url=https://www.bbc.co.uk/programmes/p02st6qs | title=Preparing for Future Epidemics | work=Health Check | publisher=BBC | location=UK | date=10 June 2015 | access-date=17 April 2020 }} The institute develops vaccines and carries out clinical trials for diseases including malaria, tuberculosis (vaccine MVA85A), ebola, and MERS-Coronavirus.{{cite news |url=https://www.bbc.co.uk/news/health-29230157 |title=Ebola vaccine trial begins |work=BBC News |date=17 September 2014}}{{cite web |url=https://www.ndm.ox.ac.uk/principal-investigators/researcher/helen-mcshane |title=Helen McShane |publisher=ndm.ox.ac.uk}}

In 2020, the institute successfully developed the Oxford–AstraZeneca COVID-19 vaccine, in a project backed by private companies including Oxford Sciences Innovation, Google Ventures, and Sequoia Capital, among others.{{cite web|date=23 November 2020|title=The Backstory: Vaccitech and its role in co-inventing the Oxford COVID-19 vaccine|url=https://www.oxfordsciencesinnovation.com/news/the-backstory-vaccitech-and-its-role-in-co-inventing-the-oxford-covid-19-vaccine/|access-date=25 March 2021|publisher=Oxford Sciences Innovation|archive-date=1 May 2021|archive-url=https://web.archive.org/web/20210501164556/https://www.oxfordsciencesinnovation.com/news/the-backstory-vaccitech-and-its-role-in-co-inventing-the-oxford-covid-19-vaccine/|url-status=live}} When developed, the UK government backed trials, purchased 100{{nbsp}}million doses, and encouraged Oxford to work with AstraZeneca, a company based in Europe, instead of Merck & Co., a US-based company; while the US gave {{US$|1.2bn}} of government funding in return for 300 million doses.{{cite news | title = The Oxford vaccine: the trials and tribulations of a world-saving jab | date = 26 June 2021 | url = https://www.theguardian.com/world/2021/jun/26/the-oxford-vaccine-the-trials-and-tribulations-of-a-world-saving-jab | work = The Guardian | access-date = 27 June 2021 | archive-date = 27 June 2021 | archive-url = https://web.archive.org/web/20210627114711/https://www.theguardian.com/world/2021/jun/26/the-oxford-vaccine-the-trials-and-tribulations-of-a-world-saving-jab | url-status = live }}{{Cite web|vauthors=Keown C|title=U.S. gives AstraZeneca $1.2 billion to fund Oxford University coronavirus vaccine — America would get 300 million doses beginning in October|url=https://www.marketwatch.com/story/us-gives-astrazeneca-12-billion-to-fund-oxford-university-coronavirus-vaccine-securing-300-million-doses-for-country-from-october-2020-05-21|access-date=30 March 2021|website=MarketWatch|archive-date=26 January 2021|archive-url=https://web.archive.org/web/20210126045250/https://www.marketwatch.com/story/us-gives-astrazeneca-12-billion-to-fund-oxford-university-coronavirus-vaccine-securing-300-million-doses-for-country-from-october-2020-05-21|url-status=live}} It collaborated with Italy's Advent Srl (part of the IRBM Group) on the development{{cite web | url=https://www.irbm.com/news/the-jenner-institute-signs-an-agreement-with-advent-to-develop-a-novel-coronavirus-vaccine/ | title=The Jenner Institute signs an agreement with Advent to develop a novel coronavirus vaccine | publisher=IRBM | access-date=18 April 2020 | archive-date=19 January 2021 | archive-url=https://web.archive.org/web/20210119190244/https://www.irbm.com/news/the-jenner-institute-signs-an-agreement-with-advent-to-develop-a-novel-coronavirus-vaccine/ | url-status=dead }} and Germany's Merck Group on the manufacture of the COVID-19 vaccine.{{cite press release |url=https://www.merckgroup.com/en/news/jenner-milestone-covid-19-vaccine-manufacturing-14-04-2020.html |title=Merck Supports Jenner Institute to Reach First Milestone in Covid-19 Vaccine Manufacturing |publisher=Merck Group |access-date=17 April 2020 }} Vaccinologist Dame Sarah Gilbert was one of the leading scientists involved in the development.{{cite journal| pmid=32305089 |pmc=7162644 | title=Sarah Gilbert: carving a path towards a COVID-19 vaccine | journal=The Lancet | volume=395 | number=10232 | page=1247 | first=Richard | last=Lane | date= 2020 | doi=10.1016/S0140-6736(20)30796-0 }}{{cite web| url=https://www.bbc.co.uk/programmes/p089xqrl | title=Prof Sarah Gilbert: Coronavirus vaccine trials to start within days | work=The Andrew Marr Show | publisher=BBC One | location=UK | date=19 April 2020 | access-date=19 April 2020 }}

The institute is named after the English physician and immunization pioneer Edward Jenner (1749–1823), who was a major contributor to the development of the smallpox vaccine.{{Cn|date=June 2021}}

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History

File:Jenner Institute Laboratories.jpg]]

File:Edward Jenner Statue.jpg at the entrance of The Jenner Institute]]

{{main|Edward Jenner Institute for Vaccine Research}}

Previously, the Edward Jenner Institute for Vaccine Research was an independent research institute named after Edward Jenner, the inventor of vaccination. It was co-located with the Compton Laboratory of the Institute for Animal Health on a campus in the village of Compton in Berkshire. After occupying temporary laboratory space at the Institute for Animal Health from 1996, the institute moved to a newly completed laboratory building in 1998. Funding of the institute continued until October 2005, when it was relaunched replacing the four founding funding partners (GlaxoSmithKline, the Medical Research Council, the Biotechnology and Biological Sciences Research Council and the Department of Health) with the University of Oxford and the Institute for Animal Health.{{cite web|url=https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/231572/1502.pdf|title=MRC Annual Report and Accounts 2005/06|page=11}}{{cite web|url=https://beta.companieshouse.gov.uk/company/03079818/filing-history?page=4|title=Annual report and financial statements for the year ended 31 March 2006}}

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References