Jonathan D. G. Jones
{{Short description|British geneticist}}
{{other people||Jonathan Jones (disambiguation){{!}}Jonathan Jones}}
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{{Infobox scientist
| name = Jonathan Jones
| honorific_suffix = {{post-nominals|country=GBR|size=100%|FRS}}
| birth_name = Jonathan Dallas George Jones
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| prizes = EMBO Membership (1998)
Member of the National Academy of Sciences (2015)
Wolf Prize in Agriculture (2025)
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| birth_date = {{Birth date and age|df=yes|1954|7|14}}{{Who's Who | title=Jones, Jonathan Dallas George | id = U22396 | author=Anon|doi=10.1093/ww/9780199540884.013.U22396|year = 1998 | edition = online Oxford University Press|location=Oxford}}
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| fields = Plant disease
Immunity
| workplaces = Harvard University
Sainsbury Laboratory
University of East Anglia
| alma_mater = University of Cambridge (BA, PhD)
| thesis_title = Repeated DNA sequences in rye (Secale cereale), wheat (Triticum aestivum) and their relatives
| thesis_url = http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.258966
| thesis_year = 1980
| doctoral_advisor = Richard B. Flavell{{Cite journal
| doi = 10.1016/0092-8674(80)90529-2
| last1 = Bedbrook | first1 = J. R.
| last2 = Jones | first2 = J.
| last3 = O'Dell | first3 = M.
| last4 = Thompson | first4 = R. D.
| last5 = Flavell | first5 = R. B.
| title = A molecular description of telometic heterochromatin in secale species
| journal = Cell
| volume = 19
| issue = 2
| pages = 545–560
| year = 1980
| pmid = 6244112
| s2cid = 31566816 }}
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| notable_students =
| known_for = Work on R genes
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| website = {{Official URL}}
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| spouse = {{marriage|Caroline Dean|1991}}
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}}
Jonathan Dallas George Jones {{post-nominals|country=GBR|FRS}} (born 14 July 1954) is a senior scientist at the Sainsbury Laboratory{{Google scholar id}} and a professor at the University of East Anglia using molecular and genetic approaches to study disease resistance in plants.{{Scopus|id=7408058559}}{{Cite journal
| last1 = Hammond-Kosack | first1 = K. E.
| last2 = Silverman | first2 = P.
| last3 = Raskin | first3 = I.
| last4 = Jones | first4 = J.
| title = Race-Specific Elicitors of Cladosporium fulvum Induce Changes in Cell Morphology and the Synthesis of Ethylene and Salicylic Acid in Tomato Plants Carrying the Corresponding Cf Disease Resistance Gene
| journal = Plant Physiology
| volume = 110
| issue = 4
| pages = 1381–1394
| year = 1996
| pmid = 12226268
| pmc = 160933
| doi = 10.1104/pp.110.4.1381
| last1 = May | first1 = M. J.
| last2 = Hammond-Kosack | first2 = K. E.
| last3 = Jones | first3 = J.
| title = Involvement of Reactive Oxygen Species, Glutathione Metabolism, and Lipid Peroxidation in the Cf-Gene-Dependent Defense Response of Tomato Cotyledons Induced by Race-Specific Elicitors of Cladosporium fulvum
| journal = Plant Physiology
| volume = 110
| issue = 4
| pages = 1367–1379
| year = 1996
| pmid = 12226267
| pmc = 160932
| doi = 10.1104/pp.110.4.1367
| last1 = English | first1 = J. J.
| last2 = Harrison | first2 = K.
| last3 = Jones | first3 = J.
| doi = 10.1105/tpc.7.8.1235
| title = Aberrant Transpositions of Maize Double Ds-Like Elements Usually Involve Ds Ends on Sister Chromatids
| journal = The Plant Cell Online
| volume = 7
| issue = 8
| pages = 1235–1247
| year = 1995
| pmid = 12242405
| pmc =160947
| last1 = Hammond-Kosack | first1 = K. E.
| last2 = Jones | first2 = D. A.
| last3 = Jones | first3 = J.
| doi = 10.1105/tpc.6.3.361
| title = Identification of Two Genes Required in Tomato for Full Cf-9-Dependent Resistance to Cladosporium fulvum
| journal = The Plant Cell Online
| volume = 6
| issue = 3
| pages = 361–374
| year = 1994
| pmid = 12244240
| pmc =160439
}}{{Cite journal | last1 = Dangl | first1 = J. L. | last2 = Jones | first2 = J. D. G. | doi = 10.1038/35081161 | title = Plant pathogens and integrated defence responses to infection | journal = Nature | volume = 411 | issue = 6839 | pages = 826–833 | year = 2001 | pmid = 11459065| bibcode = 2001Natur.411..826D | s2cid = 4345575 }}{{Cite journal | last1 = Foreman | first1 = J. | last2 = Demidchik | first2 = V. | last3 = Bothwell | first3 = J. H. F. | last4 = Mylona | first4 = P. | last5 = Miedema | first5 = H. | last6 = Torres | first6 = M. A. | last7 = Linstead | first7 = P. | last8 = Costa | first8 = S. | last9 = Brownlee | first9 = C. | last10 = Jones | first10 = J. D. G. | author-link10 = Jonathan D. G. Jones| doi = 10.1038/nature01485| last11 = Davies | first11 = J. M. | last12 = Dolan | first12 = L. | author-link12 = Liam Dolan| title = Reactive oxygen species produced by NADPH oxidase regulate plant cell growth | journal = Nature | volume = 422 | issue = 6930 | pages = 442–446 | year = 2003 | pmid = 12660786| bibcode = 2003Natur.422..442F | s2cid = 4328808 }}{{Cite journal | last1 = Hammond-Kosack | first1 = K. E. | last2 = Jones | first2 = J. D. G. | doi = 10.1146/annurev.arplant.48.1.575 | title = Plant Disease Resistance Genes | journal = Annual Review of Plant Physiology and Plant Molecular Biology | volume = 48 | pages = 575–607 | year = 1997 | pmid = 15012275| s2cid = 28215144 }}{{Cite journal | last1 = Zipfel | first1 = C. | last2 = Robatzek | first2 = S. | last3 = Navarro | first3 = L. | last4 = Oakeley | first4 = E. J. | last5 = Jones | first5 = J. D. G. | last6 = Felix | first6 = G. | last7 = Boller | first7 = T. | doi = 10.1038/nature02485 | title = Bacterial disease resistance in Arabidopsis through flagellin perception | journal = Nature | volume = 428 | issue = 6984 | pages = 764–767 | year = 2004 | pmid = 15085136| bibcode = 2004Natur.428..764Z | s2cid = 4332562 }}
Education
Jones was educated at the University of Cambridge where he studied the Natural Sciences Tripos as a student of Peterhouse, Cambridge and graduated with a Bachelor of Arts degree in 1976 followed by a PhD{{cite thesis |degree=PhD |first=Jonathan Dallas George|last=Jones |title=Repeated DNA sequences in rye (Secale cereale), wheat (Triticum aestivum) and their relatives |publisher=University of Cambridge |year=1980 |url=https://copac.jisc.ac.uk/id/31672516?style=html|website=jisc.ac.uk|id={{EThOS|uk.bl.ethos.258966}}|oclc=53605533|author-link=Jonathan D. G. Jones}} in 1980 supervised by Richard B. Flavell and Gabriel Dover.{{Cite journal |last=Viegas |first=Jennifer |date=2018-10-09 |title=Profile of Jonathan D. G. Jones |journal=Proceedings of the National Academy of Sciences |language=en |volume=115 |issue=41 |pages=10191–10194 |doi=10.1073/pnas.1815072115 |issn=0027-8424 |pmc=6187187 |pmid=30249645|bibcode=2018PNAS..11510191V |doi-access=free }}
Research and career
After his PhD, Jones did postdoctoral research at Harvard University in Frederick M. Ausubel's lab.{{EuropePMC}} Along with collaborator Jeffery Dangl, he proposed the zigzag model for the co-evolution of plant resistance genes and pathogen effectors.{{Cite journal | doi = 10.1038/nature05286 | title = The plant immune system | year = 2006 | last1 = Jones | first1 = J. D. G. | author-link1 = Jonathan D. G. Jones| last2 = Dangl | first2 = J. L. | author-link2 = Jeffery Dangl| journal = Nature | volume = 444 | pages = 323–9| pmid = 17108957 | issue = 7117 |bibcode = 2006Natur.444..323J | doi-access = free }} He also proposed the guard hypothesis, which provides a testable explanation for how plants overcome the large number of arms used by pathogens to evoke disease while having only a limited set of plant proteins to defend itself.{{Cite journal | doi = 10.1016/S0968-0004(98)01311-5 | title = Plant disease-resistance proteins and the gene-for-gene concept | first2 = J. D. G. | year = 1998 | last2 = Jones | last1 = Van Der Biezen | first1 = E. | journal = Trends in Biochemical Sciences | volume = 23 | issue = 12 | pages = 454–6| pmid=9868361}} Previously, it was thought that pattern-triggered immunity and effector-triggered immunity functioned independently, but Jones and colleagues demonstrated that these pathways are interdependent and potentiate each other, synergistically reaching an effective threshold of plant immunity.{{Cite journal |last1=Ngou |first1=Bruno Pok Man |last2=Ahn |first2=Hee-Kyung |last3=Ding |first3=Pingtao |last4=Jones |first4=Jonathan D. G. |date=April 2021 |title=Mutual potentiation of plant immunity by cell-surface and intracellular receptors |url=https://www.nature.com/articles/s41586-021-03315-7 |journal=Nature |language=en |volume=592 |issue=7852 |pages=110–115 |doi=10.1038/s41586-021-03315-7 |pmid=33692545 |issn=1476-4687}}
Jones has served as head of the Sainsbury Laboratory from 1994 to 1997 and 2003 – 2009. He is also a professor at University of East Anglia and has served as editor of The Plant Cell and
Genome Biology. Other positions he has held include:
- International Society of Plant Molecular Biology board member 1995-8
- Advisory Board 1995-8 of The Plant Journal{{citation needed|date=November 2017}}
- Editor of Plant Cell July 1998 -2004{{citation needed|date=November 2017}}
- Current Opinion in Plant Biology (COPB) Editorial Board 1997–present
- Invited Editor for COPB Plant/microbe interaction issue 1998{{citation needed|date=November 2017}}
- Editor of Genome Biology 2001–2004
- Founder of Mendel Biotechnology that has collaborated with Monsanto{{cite web|url=https://www.theguardian.com/environment/2010/jul/18/gm-scientist-defends-monsanto-links|first=Jamie |last=Doward|year=2010|website=The Guardian|title=Scientist leading GM crop test defends links to US biotech giant Monsanto}}
With George Coupland, Liam Dolan, Nicholas Harberd, Alison Mary Smith, Cathie Martin, Robert Sablowski and Abigail Amey he is a co-author of the textbook Plant Biology.{{cite book |last1=Smith |first1=Alison Mary |author-link1=Alison Mary Smith |last2=Coupand |first2=George |author-link2=George Coupland |last3=Dolan |first3=Liam |author-link3=Liam Dolan |last4=Harberd |first4=Nicholas |author-link4=Nicholas Harberd |last5=Jones |first5=Jonathan |author-link5=Jonathan D. G. Jones |last6=Martin |first6=Cathie |author-link6=Cathie Martin |last7=Sablowski |first7=Robert |last8=Amey |first8=Abigail |date=2009 |title=Plant Biology |url=https://archive.org/details/plantbiology0000unse |publisher=Garland Science |isbn=978-0815340256 |url-access=registration }}
In July 2010, Jones contributed an opinion piece to BBC News Online, outlining his stance on genetically modified (GM) food crops. In the piece, Jones argued that if we are to 'feed the planet without destroying it... we need to use every tool in our toolbox, including GM'.{{cite web|title=Fussy eaters – what's wrong with GM food?|publisher=BBC News|url=http://news.bbc.co.uk/1/hi/sci/tech/8789279.stm|location=London|first=Jonathan|last=Jones|year=2010|website=bbc.co.uk}}
=Awards and honours=
Jones was elected a Fellow of the Royal Society (FRS) in 2003{{cite web|url=https://royalsociety.org/people/jonathan-jones-11709|website=royalsociety.org|author=Anon|year=2003|title=Professor Jonathan Jones FRS|publisher=Royal Society|location=London}} One or more of the preceding sentences incorporates text from the royalsociety.org website where: {{blockquote|“All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License.” --{{Webarchive|url=https://web.archive.org/web/20161111170346/https://royalsociety.org/about-us/terms-conditions-policies/|title=Royal Society Terms, conditions and policies|date=2016-11-11}}}} and has been a member of the National Academy of Sciences since 2015.{{cite journal|last1=Viegas|first1=Jennifer|title=Profile of Jonathan D. G. Jones|journal=Proceedings of the National Academy of Sciences|volume=115|issue=41|pages=10191–10194|year=2018|issn=0027-8424|doi=10.1073/pnas.1815072115|pmid=30249645|pmc=6187187|bibcode=2018PNAS..11510191V |doi-access=free}}{{cite web|url=http://www.nasonline.org/member-directory/members/20035913.html|title=Jonathan Jones|website=nasonline.org}} He was awarded EMBO Membership in 1998. In 2025 he was awarded the Wolf Prize in Agriculture.[https://wolffund.org.il/jonathan-d-g-jones/ Wolf Prize 2025 in Agriculture]
References
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{{FRS 2003}}
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{{DEFAULTSORT:Jones, Jonathan Dallas George}}
Category:Alumni of Peterhouse, Cambridge
Category:Harvard University fellows
Category:Academics of the University of East Anglia
Category:Fellows of the Royal Society
Category:Members of the European Molecular Biology Organization
Category:Foreign associates of the National Academy of Sciences