KCNK17
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
Potassium channel subfamily K member 17 is a protein that in humans is encoded by the KCNK17 gene.{{cite journal |vauthors=Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S | title = International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels | journal = Pharmacol Rev | volume = 57 | issue = 4 | pages = 527–40 |date=Dec 2005 | pmid = 16382106 | doi = 10.1124/pr.57.4.12 | s2cid = 7356601 | url = https://escholarship.org/uc/item/3k15p5vt }}{{cite web | title = Entrez Gene: KCNK17 potassium channel, subfamily K, member 17| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=89822}}
This gene encodes K2P17.1, one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. This open channel, primarily expressed in the pancreas, is activated at alkaline pH.
See also
References
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Further reading
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- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Suzuki Y, Yamashita R, Shirota M, etal |title=Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711–8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604 | pmc=515316 }}
- {{cite journal |vauthors=Mungall AJ, Palmer SA, Sims SK, etal |title=The DNA sequence and analysis of human chromosome 6 |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055 |bibcode=2003Natur.425..805M |doi-access= free }}
- {{cite journal |vauthors=Clark HF, Gurney AL, Abaya E, etal |title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 | pmc=403697 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
- {{cite journal |vauthors=Girard C, Duprat F, Terrenoire C, etal |title=Genomic and functional characteristics of novel human pancreatic 2P domain K(+) channels |journal=Biochem. Biophys. Res. Commun. |volume=282 |issue= 1 |pages= 249–56 |year= 2001 |pmid= 11263999 |doi= 10.1006/bbrc.2001.4562 }}
- {{cite journal |vauthors=Decher N, Maier M, Dittrich W, etal |title=Characterization of TASK-4, a novel member of the pH-sensitive, two-pore domain potassium channel family |journal=FEBS Lett. |volume=492 |issue= 1–2 |pages= 84–9 |year= 2001 |pmid= 11248242 |doi=10.1016/S0014-5793(01)02222-0 |s2cid=23620127 |doi-access= |bibcode=2001FEBSL.492...84D }}
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