Karen Lam (researcher)
{{short description|Diabetes and obesity researcher}}
{{About|the researcher|the producer|Karen Lam}}
{{Infobox scientist
| fields = Medicine
| workplaces = University of Hong Kong
| alma_mater = University of Hong Kong {{Small|(MBBS, MD)}}
| known_for = Diabetes and obesity research
}}
Karen Lam Siu-ling is known for her research on diabetes and obesity. She is the Rosie T.T. Young Professor in Endocrinology and Metabolism at the University of Hong Kong.
Education and career
Lam graduated from the Diocesan Girls' School in Hong Kong in 1969{{Cite web |title=Karen Lam |url=http://www.doga.org.hk/index.php/112-interviews/old-girls-profiles/155-karen-lam |access-date=2022-02-19 |website=Diocesan Old Girls' Association}} and graduated from the University of Hong Kong medical school in 1976.{{Cite web |title=Established Endowed Professorships |url=https://www.daao.hku.hk/ephku/en/Professorship-Detail/70-Rosie-T-T-Young-Professorship-In-Endocrinology-And-Metabolism.html?f=52 |access-date=2022-02-19 |website=The University of Hong Kong Development & Alumni Affairs Office}} She received additional training at Queen Mary Hospital in Hong Kong, St Bartholomew's Hospital in London, and Tufts Medical Center in the United States.{{Cite web|title=Karen Lam, MBBS, MD|url=https://www.endocrine.org/our-community/profiles/lam-karen|access-date=2022-02-19|website=www.endocrine.org|language=en}} Lam was the first president of Diabetes Hong Kong, and has been the honorary president since 2014.{{Cite web|title=Speakers at 2017 Diabetes Malaysia conference|url=http://diabetesmalaysia.com.my/upload_dir/file/DAC%202017/DAC%202017%20-%20CV%20International%20Speakers(1).pdf|access-date=February 19, 2022|website=Diabetes Malaysia}} She was the first women to lead the department of medicine at Hong Kong University, a position she holds as of 2022. She was named the Rosie T.T. Young Professor in Endocrinology and Metabolism in 2005, and she is director of clinical trials at the University of Hong Kong.{{Cite web |last=Wong |first=Billy SK |date=2017-12-17 |title=Surge in clinical trials helps city speed new treatments to market |url=https://www.scmp.com/news/hong-kong/health-environment/article/2124635/hong-kong-helps-speed-development-new-treatments |access-date=2022-03-27 |website=South China Morning Post |language=en}}
Research
Lam's research centers on diabetes, obesity, and cardiovascular diseases, with a particular focus on hormones in fat cells. A portion of her research examines adipocyte fatty acid binding protein from fat cells, where she has provided details on where it is secreted, and its impacts on diabetes and other diseases.{{Cite news |last=Cremer |first=John |date=2009-03-14 |title=Women of Distinction: Hard work fuels quest for success |language=en |page=2 |website=South China Morning Post |url=https://www.proquest.com/docview/266687557 |url-access=subscription |access-date=2022-03-27 |id={{ProQuest|266687557}} |via=ProQuest}} She has examined adiponectin and cancer in diabetes patients,{{Cite journal|last1=Lee|first1=Chi Ho|last2=Lui|first2=David T W|last3=Cheung|first3=Chloe Y Y|last4=Fong|first4=Carol H Y|last5=Yuen|first5=Michele M A|last6=Chow|first6=Wing Sun|last7=Woo|first7=Yu Cho|last8=Xu|first8=Aimin|last9=Lam|first9=Karen S L|date=2020-04-01|title=Higher Circulating Adiponectin Concentrations Predict Incident Cancer in Type 2 Diabetes - The Adiponectin Paradox|journal=The Journal of Clinical Endocrinology and Metabolism|volume=105|issue=4|pages=e1387–e1396|doi=10.1210/clinem/dgaa075|issn=1945-7197|pmid=32072163|s2cid=211191424|doi-access=free}} and detailed therapeutic compounds in traditional Chinese medications.{{Cite journal|last1=Xu|first1=A.|last2=Wang|first2=H.|last3=Hoo|first3=R. L.|last4=Sweeney|first4=G.|last5=Vanhoutte|first5=P. M.|last6=Wang|first6=Y.|last7=Wu|first7=D.|last8=Chu|first8=W.|last9=Qin|first9=G.|last10=Lam|first10=K. S.|date=2009|title=Selective elevation of adiponectin production by the natural compounds derived from a medicinal herb alleviates insulin resistance and glucose intolerance in obese mice.|journal=Endocrinology|volume=150|issue=2|pages=625–633|doi=10.1210/en.2008-0999|issn=0013-7227|pmid=18927219|pmc=2732290}} Her research has defined connections between obesity and cardiovascular disease{{Cite journal|last1=Chow|first1=Wing Sun|last2=Tso|first2=Annette Wai Kwan|last3=Xu|first3=Aimin|last4=Yuen|first4=Michele Mae Ann|last5=Fong|first5=Carol Ho Yi|last6=Lam|first6=Tai Hing|last7=Lo|first7=Su Vui|last8=Tse|first8=Hung Fat|last9=Woo|first9=Yu Cho|last10=Yeung|first10=Chun Yip|last11=Cheung|first11=Bernard Man Yung|date=2013-01-23|title=Elevated Circulating Adipocyte‐Fatty Acid Binding Protein Levels Predict Incident Cardiovascular Events in a Community‐Based Cohort: A 12‐Year Prospective Study|journal=Journal of the American Heart Association|language=en|volume=2|issue=1|pages=e004176|doi=10.1161/JAHA.112.004176|issn=2047-9980|pmc=3603238|pmid=23525430}}{{Cite journal|last1=Lee|first1=Chi-Ho|last2=Lui|first2=David T. W.|last3=Lam|first3=Karen S. L.|date=2021|title=Adipocyte Fatty Acid-Binding Protein, Cardiovascular Diseases and Mortality|journal=Frontiers in Immunology|volume=12|page=589206|doi=10.3389/fimmu.2021.589206|issn=1664-3224|pmc=8017191|pmid=33815359|doi-access=free}} and metabolic syndrome.{{Cite journal|last1=Xu|first1=Aimin|last2=Tso|first2=Annette W.K.|last3=Cheung|first3=Bernard M.Y.|last4=Wang|first4=Yu|last5=Wat|first5=Nelson M.S.|last6=Fong|first6=Carol H.Y.|last7=Yeung|first7=Dennis C.Y.|last8=Janus|first8=Edward D.|last9=Sham|first9=Pak C.|last10=Lam|first10=Karen S.L.|date=2007-03-27|title=Circulating Adipocyte–Fatty Acid Binding Protein Levels Predict the Development of the Metabolic Syndrome|url=https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.106.647503|journal=Circulation|volume=115|issue=12|pages=1537–1543|doi=10.1161/CIRCULATIONAHA.106.647503|pmid=17389279|s2cid=9975535|doi-access=}} Lam worked to establish diabetes education in Hong Kong through specialized training of nurses and patients, both projects established with private funding.{{Cite journal|last=Harris|first=Margaret|date=2009-05-23|title=Karen Lam Siu-ling: tackling diabetes in Hong Kong|url=https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(09)60970-3/abstract|journal=The Lancet|language=English|volume=373|issue=9677|pages=1755|doi=10.1016/S0140-6736(09)60970-3|issn=0140-6736|pmid=19465220|s2cid=30592445}} In 1994 she established Hong Kong's first diabetes center at Queen Mary Hospital,{{Cite web |last=Wiseman |first=Alison |date=1994-01-25 |title=Experts call for diabetes fight to be stepped up |url=https://www.scmp.com/article/60504/experts-call-diabetes-fight-be-stepped |access-date=2022-03-27 |website=South China Morning Post |page=3 |language=en}} an idea that was later spread to other hospitals in Hong Kong.
Selected publications
- {{Cite journal|last1=Ip|first1=Mary S. M.|last2=Lam|first2=Bing|last3=Ng|first3=Matthew M. T.|last4=Lam|first4=Wah Kit|last5=Tsang|first5=Kenneth W. T.|last6=Lam|first6=Karen S. L.|date=2002-03-01|title=Obstructive Sleep Apnea Is Independently Associated with Insulin Resistance|url=https://www.atsjournals.org/doi/full/10.1164/ajrccm.165.5.2103001|journal=American Journal of Respiratory and Critical Care Medicine|volume=165|issue=5|pages=670–676|doi=10.1164/ajrccm.165.5.2103001|pmid=11874812|issn=1073-449X}}
- {{Cite journal|last1=Xu|first1=Aimin|last2=Lam|first2=Michael C.|last3=Chan|first3=Kok Weng|last4=Wang|first4=Yu|last5=Zhang|first5=Jialiang|last6=Hoo|first6=Ruby L. C.|last7=Xu|first7=Jian Yu|last8=Chen|first8=Baoying|last9=Chow|first9=Wing-Sun|last10=Tso|first10=Annette W. K.|last11=Lam|first11=Karen S. L.|date=2005-04-26|title=Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice|journal=Proceedings of the National Academy of Sciences|language=en|volume=102|issue=17|pages=6086–6091|doi=10.1073/pnas.0408452102|issn=0027-8424|pmc=1087912|pmid=15837923|bibcode=2005PNAS..102.6086X |doi-access=free}}
- {{Cite journal|last1=Ong|first1=Kwok Leung|last2=Cheung|first2=Bernard M.Y.|last3=Man|first3=Yu Bun|last4=Lau|first4=Chu Pak|last5=Lam|first5=Karen S.L.|date=2007-01-01|title=Prevalence, Awareness, Treatment, and Control of Hypertension Among United States Adults 1999–2004|journal=Hypertension|volume=49|issue=1|pages=69–75|doi=10.1161/01.HYP.0000252676.46043.18|pmid=17159087|s2cid=29728577|doi-access=free}}
- {{Cite journal|last1=Cheung|first1=Bernard M. Y.|last2=Ong|first2=Kwok Leung|last3=Cherny|first3=Stacey S.|last4=Sham|first4=Pak-Chung|last5=Tso|first5=Annette W. K.|last6=Lam|first6=Karen S. L.|date=2009-05-01|title=Diabetes Prevalence and Therapeutic Target Achievement in the United States, 1999 to 2006|url=https://www.amjmed.com/article/S0002-9343(08)01186-8/abstract|journal=The American Journal of Medicine|language=English|volume=122|issue=5|pages=443–453|doi=10.1016/j.amjmed.2008.09.047|pmid=19375554|issn=0002-9343}}
Awards and honors
In 2008, Lam was honored as by the Hong Kong Women Professional and Entrepreneurs' Association for her work on hormones that help fight diabetes.{{Cite news|date=5 July 2008|title=Honors for outstanding women|pages=3|work=South China Morning Post|via=ProQuest}}
References
{{reflist}}
External links
- {{google scholar id|107dfr8AAAAJ}}
{{Authority control}}
{{DEFAULTSORT:Lam, Karen}}
Category:Alumni of the University of Hong Kong
Category:Academic staff of the University of Hong Kong
Category:Women medical researchers