Kent C. Berridge

{{Infobox scientist

| name = Kent Berridge

| alma_mater = University of California, Davis (BS)
University of Pennsylvania (PhD)

| birth_date = {{birth year and age|1957}}

}}

Kent C. Berridge[https://lsa.umich.edu/psych/research&labs/berridge/researchteam/kent_berridge/index.html Berridge's homepage at the University of Michigan], retrieved October 11, 2006 (born 1957) is an American academic, currently working as a professor of psychology (biopsychology) and neuroscience at the University of Michigan. Berridge was a joint winner of the 2018 Grawemeyer Award for Psychology.{{cite web|url=http://grawemeyer.org/psychology/|title=Grawemeyer Awards, Psychology|publisher=grawemeyer.org|accessdate=2018-12-06}}

Early life and education

Berridge was born in 1957.{{Cite web|url=https://lsa.umich.edu/psych/news-events/all-news/faculty-news/the-50-most-influential-living-psychologists-in-the-world.html|title=Kent Berridge Named One of the 50 Most Influential Living Psychologists in the World {{!}} U-M LSA Department of Psychology|website=lsa.umich.edu|language=en|access-date=2020-04-11}} Berridge earned a Bachelor of Science from the University of California, Davis in 1979, followed by a PhD from the University of Pennsylvania in 1983.{{Cite web|url=https://lsa.umich.edu/psych/research&labs/berridge/researchteam/kent_berridge/index.html|title = Kent Berridge Affective Neuroscience & Biopsychology Lab}}

Research

Berridge conducts research relating to brain systems of motivation, affect, reward “liking”, reward “wanting”, emotion, fear, pleasure, drug addiction, eating disorders, and decision utility. He also studies natural syntactical chains of behavior (e.g. grooming; taste response patterns) in animals with colleague Dr. J. Wayne Aldridge. With Dr. Piotr Winkielman, he has investigated the issue of unconscious emotion in humans.

= Liking =

Berridge is known for his work on the brain systems for pleasure (“liking”).Berridge, K.C. Pleasures of the Brain. Brain Cogn. 2003 Jun;52(1):106-28. Using an assay for “liking” called Taste Reactivity Analysis developed by taste researchers, Berridge measures facial palatability responses to tastes, which are similar between rodents, primates and humans.[http://www.lsa.umich.edu/psych/research&labs/berridge/VideoIndex.htm Videos of Pleasure-elicited Reactions] {{Webarchive|url=https://web.archive.org/web/20180125013114/https://lsa.umich.edu/psych/research%26labs/berridge/VideoIndex.htm |date=2018-01-25 }}. When something enjoyably sweet is tasted, characteristic licking responses occur. When something aversively bitter is tasted, gaping and head shaking occur. Berridge has helped identify "hedonic hotspots" in the brain, such as the nucleus accumbens and ventral pallidum, where opioid, endocannabinoid, and GABA neurotransmission coordinate the “liking” of tastes. Berridge postulates that these hedonic hotspots may be crucial for how the brain produces the hedonic pleasurable feelings common to delicious food, sex, drugs, and other rewards (a role previously thought to be played mostly by brain dopamine systems).

= Addiction =

Berridge and colleague Dr. Terry Robinson have formulated a contemporary theory of addiction called the Incentive Sensitization Theory of Addiction.Robinson, T.E., Berridge, K.C. The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Res Brain Res Rev. 1993 Sep-Dec;18(3):247-91. According to this theory, drug addiction develops from a sensitization of the mesolimbic dopamine system. Dopamine normally functions to attribute incentive salience to stimuli associated with rewards like food and sex, and triggers reward “wanting”. Drugs hijack this “wanting” system. Following repeated use of drugs, the dopamine system becomes hyper-responsive and drug cues become hyper-salient. This means drug cues are nearly impossible for addicts to ignore, and when they are encountered they can lead to intense cravings and/or relapse. This sensitized cue-triggered drug 'wanting' can persist for years after an addict quits drugs, and long after drug withdrawal has ceased. This fact may account for the tendency of former addicts to relapse to drug use after quitting, sometimes even after many years of abstinence.

= Dopamine =

Berridge and Robinson helped redefine the role of mesolimbic dopamine in the brain,Berridge, K.C., Robinson, T.E. What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience? Brain Res Brain Res Rev. 1998 Dec;28(3):309-69. which had previously been viewed as a pleasure neurotransmitter. Dopamine is no longer widely regarded as a pleasure transmitter. Instead, dopamine is thought to mediate reward, that is, to attribute incentive salience to reward-associated stimuli.