Keyser Brook

{{Use American English|date=February 2025}}

{{Infobox river

| name = Keyser Brook

| name_native =

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| pushpin_map = New York

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| pushpin_map_caption= Location of the mouth of Keyser Brook

| subdivision_type1 = Country

| subdivision_name1 = United States

| subdivision_type2 = State

| subdivision_name2 = New York

| subdivision_type3 =

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| subdivision_type4 = County

| subdivision_name4 = Delaware

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| source1_coordinates= {{coord|42.5228548|-74.8034876|format=dms}}

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| mouth = Charlotte Creek

| mouth_location =

| mouth_coordinates = {{coord|42.4897998|-74.8065440|display=inline,title|format=dms}}{{cite gnis

| id = 979692

| name = Keyser Brook

| accessdate = 2018-09-24}}

| mouth_elevation = {{convert|1283|ft|abbr=on}}

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Keyser Brook is a river in Delaware County, New York and Otsego County, New York. It flows into Charlotte Creek east-northeast of Davenport.