Killjoy

• Margaret Killjoy, American author and musician
• Killjoy (musician) (1969–2018), American vocalist

• Killjoy, in Charlton Comics' E-Man series
• Killjoy, in the video game Valorant
• Killjoy, in the Marvel Comics series Weapon P.R.I.M.E.
• Killjoy, in the movie The Ice Pirates
• Dr. Killjoy, in the video game The Suffering
• Katie Killjoy, in the adult animation series Hazbin Hotel
• The Fabulous Killjoys, from the band My Chemical Romance

• Killjoy, a 1981 made-for-television movie starring Kim Basinger
• Killjoy (film series), a series of 6 horror films featuring the eponymous clown Killjoy
• Killjoy (2000 film), the first installment, from 2000
• Killjoy 2: Deliverance from Evil, a 2002 sequel
• Killjoy 3, a 2010 sequel
• Killjoy Goes to Hell, a 2012 sequel
• Killjoys, a 2015 science fiction television series

• The Killjoys (Australian band), a 1980s Australian pop-folk band
• The Killjoys (Canadian band), a 1990s Canadian alternative rock band
• The Killjoys (UK band), late 1970s UK punk rock/new wave band
• Killjoy (Shihad album), 1995
• Killjoy (Fox Stevenson album), 2019
• Killjoy (Coach Party album), 2023
• "The Killjoy", a song by Insomnium from the album Above the Weeping World
• "Mr. Killjoy", a song by Lordi from the special edition of the album The Arockalypse
• Danger Days: The True Lives of the Fabulous Killjoys (My Chemical Romance album)

• Killjoy, a 2002 novel by Julie Garwood
• (Our Sister) Killjoy, a 1977 novel by Ama Ata Aidoo
• The True Lives of the Fabulous Killjoys (2013-2014), graphic novel by Gerard Way

• Killjoy, the NATO reporting name of the Kh-47M2 Kinzhal missile

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