L1TD1

{{Short description|Protein-coding gene in the species Homo sapiens}}

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LINE-1 type transposase domain containing 1, also known as L1TD1, is an RNA-binding protein that involved with self-renewal of undifferentiated human embryonic stem cells and cancer cell proliferation. L1TD1 has been reported to associate with the development of several cancers.

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cite journal |vauthors=Iwabuchi KA, Yamakawa T, Sato Y, Ichisaka T, Takahashi K, Okita K, Yamanaka S |

title = ECAT11/L1td1 is enriched in ESCs and rapidly activated during iPSC generation, but it is dispensable for the maintenance and induction of pluripotency |

journal = PLOS ONE |

volume = 6 |

issue = 5 |

pages = e20461 |date=May 2011 |

pmid = 21637830 |

doi = 10.1371/journal.pone.0020461 |

issn =

| pmc=3102727

|

bibcode = 2011PLoSO...620461I |

doi-access = free }}

{{

cite journal |vauthors=Närvä E, Rahkonen N, Emani MR, Lund R, Pursiheimo JP, Nästi J, Autio R, Rasool O, Denessiouk K, Lähdesmäki H, Rao A, Lahesmaa R |

title = RNA-binding protein L1TD1 interacts with LIN28 via RNA and is required for human embryonic stem cell self-renewal and cancer cell proliferation |

journal = Stem Cells |

volume = 30 |

issue = 3 |

pages = 452–60 |date=March 2012 |

pmid = 22162396 |

doi = 10.1002/stem.1013 |

url = |

issn =

| pmc=3507993

}}

{{

cite journal |vauthors=Wong RC, Ibrahim A, Fong H, Thompson N, Lock LF, Donovan PJ |

title = L1TD1 is a marker for undifferentiated human embryonic stem cells |

journal = PLOS ONE |

volume = 6 |

issue = 4 |

pages = e19355 |date=April 2011 |

pmid = 21559406 |

doi = 10.1371/journal.pone.0019355 |

issn =

| pmc=3084827

|

bibcode = 2011PLoSO...619355W |

doi-access = free }}

{{

cite journal |vauthors=Yamamoto E, Toyota M, Suzuki H, Kondo Y, Sanomura T, Murayama Y, Ohe-Toyota M, Maruyama R, Nojima M, Ashida M, Fujii K, Sasaki Y, Hayashi N, Mori M, Imai K, Tokino T, Shinomura Y |

title = LINE-1 hypomethylation is associated with increased CpG island methylation in Helicobacter pylori-related enlarged-fold gastritis |

journal = Cancer Epidemiol Biomarkers Prev |

volume = 17 |

issue = 10 |

pages = 2555–64 |date=October 2008 |

pmid = 18842996 |

doi = 10.1158/1055-9965.EPI-08-0112|

url = http://cebp.aacrjournals.org/content/17/10/2555.long |

issn =

|

doi-access = |

s2cid = 24719399 |

url-access = subscription }}