LANCL1

{{Short description|Protein-coding gene in the species Homo sapiens}}

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LanC like 1 is a protein that in humans is encoded by the LANCL1 gene.

{{cite web

| title = Entrez Gene: LanC like 1

| url = https://www.ncbi.nlm.nih.gov/gene/10314

| access-date = 2016-04-20

}}

Function

This gene encodes a loosely associated peripheral membrane protein related to the LanC family of bacterial membrane-associated proteins involved in the biosynthesis of antimicrobial peptides. This protein may play a role as a peptide-modifying enzyme component in eukaryotic cells. Previously considered a member of the G-protein-coupled receptor superfamily, this protein is now in the LanC family. Multiple alternatively spliced variants, encoding the same protein, have been identified.

References

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Further reading

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  • {{cite journal |vauthors=Zhang W, Wang L, Liu Y, Xu J, Zhu G, Cang H, Li X, Bartlam M, Hensley K, Li G, Rao Z, Zhang XC |title=Structure of human lanthionine synthetase C-like protein 1 and its interaction with Eps8 and glutathione |journal=Genes Dev. |volume=23 |issue=12 |pages=1387–92 |year=2009 |pmid=19528316 |pmc=2701572 |doi=10.1101/gad.1789209 }}

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