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LIN7A

{{Short description|Protein-coding gene in humans}}

{{Infobox_gene}}

Lin-7 homolog A is a protein that in humans is encoded by the LIN7A gene.{{cite journal | vauthors = Jo K, Derin R, Li M, Bredt DS | title = Characterization of MALS/Velis-1, -2, and -3: a family of mammalian LIN-7 homologs enriched at brain synapses in association with the postsynaptic density-95/NMDA receptor postsynaptic complex | journal = J Neurosci | volume = 19 | issue = 11 | pages = 4189–99 | date = Jun 1999 | pmid = 10341223 | pmc = 6782594| doi = 10.1523/JNEUROSCI.19-11-04189.1999| doi-access = free }}{{cite journal | vauthors = Bohl J, Brimer N, Lyons C, Vande Pol SB | title = The stardust family protein MPP7 forms a tripartite complex with LIN7 and DLG1 that regulates the stability and localization of DLG1 to cell junctions | journal = J Biol Chem | volume = 282 | issue = 13 | pages = 9392–400 | date = Mar 2007 | pmid = 17237226 | doi = 10.1074/jbc.M610002200 | doi-access = free }}{{cite web | title = Entrez Gene: LIN7A lin-7 homolog A (C. elegans)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8825}}

Interactions

LIN7A has been shown to interact with:

  • CASK,{{cite journal | vauthors = Borg JP, Straight SW, Kaech SM, de Taddéo-Borg M, Kroon DE, Karnak D, Turner RS, Kim SK, Margolis B | title = Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting | journal = J. Biol. Chem. | volume = 273 | issue = 48 | pages = 31633–6 | date = Nov 1998 | pmid = 9822620 | doi = 10.1074/jbc.273.48.31633| doi-access = free }}
  • DLG1, and
  • KCNJ12.{{cite journal | vauthors = Leonoudakis D, Conti LR, Radeke CM, McGuire LM, Vandenberg CA | title = A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels | journal = J. Biol. Chem. | volume = 279 | issue = 18 | pages = 19051–63 | date = Apr 2004 | pmid = 14960569 | doi = 10.1074/jbc.M400284200 | doi-access = free }}{{cite journal | vauthors = Leonoudakis D, Conti LR, Anderson S, Radeke CM, McGuire LM, Adams ME, Froehner SC, Yates JR, Vandenberg CA | title = Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins | journal = J. Biol. Chem. | volume = 279 | issue = 21 | pages = 22331–46 | date = May 2004 | pmid = 15024025 | doi = 10.1074/jbc.M400285200 | doi-access = free }}

References

{{reflist|2}}

Further reading

{{refbegin | 2}}

  • {{cite journal | vauthors = Rousset R, Fabre S, Desbois C, Bantignies F, Jalinot P | title = The C-terminus of the HTLV-1 Tax oncoprotein mediates interaction with the PDZ domain of cellular proteins | journal = Oncogene | volume = 16 | issue = 5 | pages = 643–54 | year = 1998 | pmid = 9482110 | doi = 10.1038/sj.onc.1201567 | doi-access = free }}
  • {{cite journal | vauthors = Butz S, Okamoto M, Südhof TC | title = A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain | journal = Cell | volume = 94 | issue = 6 | pages = 773–82 | year = 1998 | pmid = 9753324 | doi = 10.1016/S0092-8674(00)81736-5 | s2cid = 12465062 | doi-access = free }}
  • {{cite journal | vauthors = Borg JP, Straight SW, Kaech SM, de Taddéo-Borg M, Kroon DE, Karnak D, Turner RS, Kim SK, Margolis B | title = Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting | journal = J. Biol. Chem. | volume = 273 | issue = 48 | pages = 31633–6 | year = 1998 | pmid = 9822620 | doi = 10.1074/jbc.273.48.31633 | doi-access = free }}
  • {{cite journal | vauthors = Borg JP, Lõpez-Figueroa MO, de Taddèo-Borg M, Kroon DE, Turner RS, Watson SJ, Margolis B | title = Molecular analysis of the X11-mLin-2/CASK complex in brain | journal = J. Neurosci. | volume = 19 | issue = 4 | pages = 1307–16 | year = 1999 | pmid = 9952408 | doi = 10.1523/JNEUROSCI.19-04-01307.1999| pmc = 6786035 | doi-access = free }}
  • {{cite journal | vauthors = Perego C, Vanoni C, Villa A, Longhi R, Kaech SM, Fröhli E, Hajnal A, Kim SK, Pietrini G | title = PDZ-mediated interactions retain the epithelial GABA transporter on the basolateral surface of polarized epithelial cells | journal = EMBO J. | volume = 18 | issue = 9 | pages = 2384–93 | year = 1999 | pmid = 10228153 | pmc = 1171321 | doi = 10.1093/emboj/18.9.2384 }}
  • {{cite journal | vauthors = Kamberov E, Makarova O, Roh M, Liu A, Karnak D, Straight S, Margolis B | title = Molecular cloning and characterization of Pals, proteins associated with mLin-7 | journal = J. Biol. Chem. | volume = 275 | issue = 15 | pages = 11425–31 | year = 2000 | pmid = 10753959 | doi = 10.1074/jbc.275.15.11425 | doi-access = free }}
  • {{cite journal | vauthors = Tseng TC, Marfatia SM, Bryant PJ, Pack S, Zhuang Z, O'Brien JE, Lin L, Hanada T, Chishti AH | title = VAM-1: a new member of the MAGUK family binds to human Veli-1 through a conserved domain | journal = Biochim. Biophys. Acta | volume = 1518 | issue = 3 | pages = 249–59 | year = 2001 | pmid = 11311936 | doi = 10.1016/s0167-4781(01)00191-9 }}
  • {{cite journal | vauthors = Harris BZ, Venkatasubrahmanyam S, Lim WA | title = Coordinated folding and association of the LIN-2, -7 (L27) domain. An obligate heterodimerization involved in assembly of signaling and cell polarity complexes | journal = J. Biol. Chem. | volume = 277 | issue = 38 | pages = 34902–8 | year = 2002 | pmid = 12110687 | doi = 10.1074/jbc.M205856200 | doi-access = free }}
  • {{cite journal | vauthors = Hori K, Konno D, Maruoka H, Sobue K | title = MALS is a binding partner of IRSp53 at cell-cell contacts | journal = FEBS Lett. | volume = 554 | issue = 1–2 | pages = 30–4 | year = 2003 | pmid = 14596909 | doi = 10.1016/S0014-5793(03)01074-3 | s2cid = 30329043 | doi-access = free }}
  • {{cite journal | vauthors = Leonoudakis D, Conti LR, Radeke CM, McGuire LM, Vandenberg CA | title = A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels | journal = J. Biol. Chem. | volume = 279 | issue = 18 | pages = 19051–63 | year = 2004 | pmid = 14960569 | doi = 10.1074/jbc.M400284200 | doi-access = free }}
  • {{cite journal | vauthors = Leonoudakis D, Conti LR, Anderson S, Radeke CM, McGuire LM, Adams ME, Froehner SC, Yates JR, Vandenberg CA | title = Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins | journal = J. Biol. Chem. | volume = 279 | issue = 21 | pages = 22331–46 | year = 2004 | pmid = 15024025 | doi = 10.1074/jbc.M400285200 | doi-access = free }}
  • {{cite journal | vauthors = Olsen O, Wade JB, Morin N, Bredt DS, Welling PA | title = Differential localization of mammalian Lin-7 (MALS/Veli) PDZ proteins in the kidney | journal = Am. J. Physiol. Renal Physiol. | volume = 288 | issue = 2 | pages = F345–52 | year = 2005 | pmid = 15494546 | doi = 10.1152/ajprenal.00235.2004 | s2cid = 36221552 }}
  • {{cite journal | vauthors = Dode L, Andersen JP, Raeymaekers L, Missiaen L, Vilsen B, Wuytack F | title = Functional comparison between secretory pathway Ca2+/Mn2+-ATPase (SPCA) 1 and sarcoplasmic reticulum Ca2+-ATPase (SERCA) 1 isoforms by steady-state and transient kinetic analyses | journal = J. Biol. Chem. | volume = 280 | issue = 47 | pages = 39124–34 | year = 2006 | pmid = 16192278 | doi = 10.1074/jbc.M506181200 | doi-access = free }}

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