LIPID MAPS

{{infobox biodatabase

|title = LIPID MAPS

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|description = Lipidomics

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|pmid = 17584797

|released = 2003

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|url = www.lipidmaps.org

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LIPID MAPS (Lipid Metabolites and Pathways Strategy) is a web portal designed to be a gateway to Lipidomics resources. The resource has spearheaded a classification of biological lipids, dividing them into eight general categories.{{cite journal | vauthors = Fahy E, Subramaniam S, Murphy RC, Nishijima M, Raetz CR, Shimizu T, Spener F, van Meer G, Wakelam MJ, Dennis EA | title = Update of the LIPID MAPS comprehensive classification system for lipids | journal = Journal of Lipid Research | volume = 50 Suppl | issue = S1 | pages = S9-14 | date = April 2009 | pmid = 19098281 | pmc = 2674711 | doi = 10.1194/jlr.R800095-JLR200 |doi-access=free}} LIPID MAPS provides standardised methodologies for mass spectrometry analysis of lipids, e.g.{{cite journal| doi =10.1590/S0004-2803.201900000-80 | volume=56 | title=STUDY OF LIPID BIOMARKERS OF PATIENTS WITH POLYPS AND COLORECTAL CÂNCER | journal=Arquivos de Gastroenterologia | pages=399–404 | vauthors=Valeria Pereira Serafim P, Figueiredo JR, de Adiel G, Vitor Felipe A, Guimaraes Lo Turco E, Silva, Manoukian Forones N| year=2019 | issue=4 | pmid=31800736 | doi-access=free}}{{cite journal| doi =10.1002/rcm.8557 | volume=34 | title=Characterization of pharmaceutic structured triacylglycerols by high‐performance liquid chromatography/tandem high‐resolution mass spectrometry and its application to structured fat emulsion injection | year=2020 | journal=Rapid Communications in Mass Spectrometry | vauthors=Zheng H, Yang R, Wang Z, Wang J, Zhang J, Sun H| issue=1 | pages=e8557 | pmid=31429125 | doi-access=}}{{cite journal| doi =10.1529/biophysj.108.129197 | volume=95 | title=Aggregation Behavior of an Ultra-Pure Lipopolysaccharide that Stimulates TLR-4 Receptors | year=2008 | journal=Biophysical Journal | pages=986–993 | vauthors=Sasaki H, White SH| issue=2 | pmid=18375521 | pmc=2440428 | bibcode=2008BpJ....95..986S}}

LIPID MAPS has been cited as evidence of a growing appreciation of the study of lipid metabolism{{cite journal| doi = 10.2217/17460875.2.4.403 | volume=2 | title=Role of lipids in brain injury and diseases | year=2007 | journal=Future Lipidology | pages=403–422 | vauthors=Muralikrishna Adibhatla R, Hatcher JF| issue=4 | pmid=18176634 | pmc=2174836}} and the rapid development and standardisation of the lipidomics field {{cite news

| author =

| title = Phat on potential, lipidomics is gaining weight

| url = https://www.eurekalert.org/pub_releases/2019-01/bi-pop011019.php

| work = Eureka Alert

| location =

| date = 10 January 2019

| access-date = 10 June 2020

}}

{{cite news

| author =

| title = Lipidomics – A Niche but Rapidly Growing Field

| url = https://www.technologynetworks.com/diagnostics/articles/lipidomics-a-niche-but-rapidly-growing-field-323858

| work = Technology Networks

| location =

| date = 11 September 2019

| access-date = 10 June 2020

}}

Key LIPID MAPS resources include:

• LIPID MAPS Structure Database (LMSD) - a database of structures and annotations of biologically relevant lipids,{{cite journal | pmid = 17098933 | doi=10.1093/nar/gkl838 | volume=35 | title=LMSD: LIPID MAPS structure database | pmc=1669719 | date=January 2007 | journal=Nucleic Acids Res. | pages=D527–32 | vauthors=Sud M, Fahy E, Cotter D | issue=Database issue | display-authors = etal}} containing over 49000 different lipids. The paper describing this resource has, according to PubMed, been cited more than 200 times.
• LIPID MAPS In-Silico Structure Database (LMISSD) - a database of computationally predicted lipids generated by expansion of headgroups for commonly occurring lipid classes
• LIPID MAPS Gene/Proteome Database (LMPD) - a database of genes and gene products which are involved in lipid metabolism{{cite journal | pmid = 16381922 | doi=10.1093/nar/gkj122 | volume=34 | title=LMPD: LIPID MAPS proteome database | pmc=1347484 | date=January 2006 | journal=Nucleic Acids Res. | pages=D507–10 | vauthors=Cotter D, Maer A, Guda C, Saunders B, Subramaniam S | issue=90001}}

Tools available from LIPID MAPS enable scientists to identify likely lipids in their samples from mass spectrometry data, a common method to analyse lipids in biological specimens. In particular, LipidFinder {{cite journal | pmid = 30101336 | doi=10.1093/bioinformatics/bty679 | volume=35 | title=LipidFinder on LIPID MAPS: peak filtering, MS searching and statistical analysis for lipidomics | pmc=6378932 | year=2019 | journal=Bioinformatics | pages=685–687 | vauthors=Fahy E, Alvarez-Jarreta J, Brasher CJ, Nguyen A, Hawksworth JI, Rodrigues P, Meckelmann S, Allen SM, O'Donnell VB | issue=4}} enables analysis of MS data. Tutorials and educational material on lipids are also available at the site.{{cite journal | vauthors = Sud M, Fahy E, Cotter D, Dennis EA, Subramaniam S | title = LIPID MAPS-Nature Lipidomics Gateway: An Online Resource for Students and Educators Interested in Lipids | journal = Journal of Chemical Education | volume = 89 | pages = 291–292 | date = December 2011 | issue = 2 | pmid = 24764601 | pmc = 3995124 | doi = 10.1021/ed200088u}}

In January 2020, LIPID MAPS became an ELIXIR service.{{cite web

|url=https://elixir-europe.org/services/list?field_scientific_domain_tid=All&field_elixir_badge_tid=All&field_type_of_service_tid=All&field_elixir_node_target_id=992&combine=lipid

|title= Service list

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|website= elixir-europe.org

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|access-date= 10 June 2020

|quote=}} and in 2024 a core data resource. In addition, it joined Global Biodata Coalition as a core biodata resource.{{cite web

|url=https://www.cardiff.ac.uk/news/view/2787471-global-data-resource-lipid-maps-awarded-two-international-badges-of-excellence

|title= Global data resource LIPID MAPS awarded two international badges of excellence

|access-date= 25 July 2024

|quote=}}