LMO7

{{Short description|Protein-coding gene in the species Homo sapiens}}

LIM domain only protein 7 is a protein that in humans is encoded by the LMO7 gene.{{cite journal |vauthors=Putilina T, Jaworski C, Gentleman S, McDonald B, Kadiri M, Wong P | title = Analysis of a human cDNA containing a tissue-specific alternatively spliced LIM domain | journal = Biochem Biophys Res Commun | volume = 252 | issue = 2 | pages = 433–9 |date=Dec 1998 | pmid = 9826547 | doi = 10.1006/bbrc.1998.9656 | url = https://zenodo.org/record/1229492 }}{{cite journal |vauthors=Cenciarelli C, Chiaur DS, Guardavaccaro D, Parks W, Vidal M, Pagano M | title = Identification of a family of human F-box proteins | journal = Curr Biol | volume = 9 | issue = 20 | pages = 1177–9 |date=Dec 1999 | pmid = 10531035 | doi = 10.1016/S0960-9822(00)80020-2 | doi-access = free | bibcode = 1999CBio....9.1177C }}{{cite web | title = Entrez Gene: LMO7 LIM domain 7| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4008}}

This gene encodes a protein containing a calponin homology (CH) domain, a PDZ domain, and a LIM domain. An F-box (FBX) domain is present in alternative splice variants. Members of the LIM protein family carry the LIM domain, a unique cysteine-rich zinc-binding domain. Members of the FBX protein family are involved in protein-protein interactions. The encoded protein may be involved in protein-protein interactions. Multiple alternative splice variants have been described but their full-length sequences have not been determined.

References

{{cite journal |vauthors=Nakajima D, Okazaki N, Yamakawa H, etal |title=Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones |journal=DNA Res. |volume=9 |issue= 3 |pages= 99–106 |year= 2003 |pmid= 12168954 |doi=10.1093/dnares/9.3.99 |doi-access=free }}
{{cite journal |vauthors=Nagase T, Ishikawa K, Suyama M, etal |title=Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro |journal=DNA Res. |volume=5 |issue= 6 |pages= 355–64 |year= 1999 |pmid= 10048485 |doi=10.1093/dnares/5.6.355 |doi-access=free }}
{{cite journal |vauthors=Rozenblum E, Vahteristo P, Sandberg T, etal |title=A genomic map of a 6-Mb region at 13q21-q22 implicated in cancer development: identification and characterization of candidate genes |journal=Hum. Genet. |volume=110 |issue= 2 |pages= 111–21 |year= 2002 |pmid= 11935316 |doi= 10.1007/s00439-001-0646-6 |s2cid=21371347 |url=https://zenodo.org/record/1232709 }}
{{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
{{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |doi-access= free }}
{{cite journal |vauthors=Beausoleil SA, Jedrychowski M, Schwartz D, etal |title=Large-scale characterization of HeLa cell nuclear phosphoproteins |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 | pmc=514446 |bibcode=2004PNAS..10112130B |doi-access=free }}
{{cite journal |vauthors=Jin J, Smith FD, Stark C, etal |title=Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization |journal=Curr. Biol. |volume=14 |issue= 16 |pages= 1436–50 |year= 2004 |pmid= 15324660 |doi= 10.1016/j.cub.2004.07.051 |s2cid=2371325 |doi-access=free |bibcode=2004CBio...14.1436J }}
{{cite journal |vauthors=Benzinger A, Muster N, Koch HB, etal |title=Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer |journal=Mol. Cell. Proteomics |volume=4 |issue= 6 |pages= 785–95 |year= 2005 |pmid= 15778465 |doi= 10.1074/mcp.M500021-MCP200 |doi-access= free }}
{{cite journal |vauthors=Kim J, Bhinge AA, Morgan XC, Iyer VR |title=Mapping DNA-protein interactions in large genomes by sequence tag analysis of genomic enrichment |journal=Nat. Methods |volume=2 |issue= 1 |pages= 47–53 |year= 2005 |pmid= 15782160 |doi= 10.1038/nmeth726 |s2cid=6135437 }}
{{cite journal |vauthors=Kim JE, Tannenbaum SR, White FM |title=Global phosphoproteome of HT-29 human colon adenocarcinoma cells |journal=J. Proteome Res. |volume=4 |issue= 4 |pages= 1339–46 |year= 2005 |pmid= 16083285 |doi= 10.1021/pr050048h }}
{{cite journal |vauthors=Iwabuchi K, Kaneko T, Kikuyama M |title=Ionic mechanism of mechano-perception in Characeae |journal=Plant Cell Physiol. |volume=46 |issue= 11 |pages= 1863–71 |year= 2006 |pmid= 16192285 |doi= 10.1093/pcp/pci204 |doi-access= free }}
{{cite journal |vauthors=Beausoleil SA, Villén J, Gerber SA, etal |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285–92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240 |s2cid=14294292 }}
{{cite journal |vauthors=Holaska JM, Rais-Bahrami S, Wilson KL |title=Lmo7 is an emerin-binding protein that regulates the transcription of emerin and many other muscle-relevant genes |journal=Hum. Mol. Genet. |volume=15 |issue= 23 |pages= 3459–72 |year= 2007 |pmid= 17067998 |doi= 10.1093/hmg/ddl423 |doi-access= free }}
{{cite journal |vauthors=Olsen JV, Blagoev B, Gnad F, etal |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 |doi-access= free }}

LMO7

References

Further reading