LPAR5

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{cs1 config|name-list-style=vanc|display-authors=6}}

{{Infobox_gene}}

Lysophosphatidic acid receptor 5 also known as LPA5 is a protein that in humans is encoded by the LPAR5 gene.{{cite journal | vauthors = | title = Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23 | journal = Nature Genetics | volume = 26 | issue = 3 | pages = 345–348 | date = November 2000 | pmid = 11062477 | doi = 10.1038/81664 | s2cid = 38870810 }}{{cite journal | vauthors = Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF | title = Discovery and mapping of ten novel G protein-coupled receptor genes | journal = Gene | volume = 275 | issue = 1 | pages = 83–91 | date = September 2001 | pmid = 11574155 | doi = 10.1016/S0378-1119(01)00651-5 }}{{cite journal | vauthors = Lee CW, Rivera R, Gardell S, Dubin AE, Chun J | title = GPR92 as a new G12/13- and Gq-coupled lysophosphatidic acid receptor that increases cAMP, LPA5 | journal = The Journal of Biological Chemistry | volume = 281 | issue = 33 | pages = 23589–23597 | date = August 2006 | pmid = 16774927 | doi = 10.1074/jbc.M603670200 | doi-access = free }}{{cite journal | vauthors = Kotarsky K, Boketoft A, Bristulf J, Nilsson NE, Norberg A, Hansson S, Owman C, Sillard R, Leeb-Lundberg LM, Olde B | title = Lysophosphatidic acid binds to and activates GPR92, a G protein-coupled receptor highly expressed in gastrointestinal lymphocytes | journal = The Journal of Pharmacology and Experimental Therapeutics | volume = 318 | issue = 2 | pages = 619–628 | date = August 2006 | pmid = 16651401 | doi = 10.1124/jpet.105.098848 | s2cid = 5989815 }}{{cite web | title = Entrez Gene: GPR92 G protein-coupled receptor 92| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57121}} LPA5 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).{{cite journal | vauthors = Choi JW, Herr DR, Noguchi K, Yung YC, Lee CW, Mutoh T, Lin ME, Teo ST, Park KE, Mosley AN, Chun J | title = LPA receptors: subtypes and biological actions | journal = Annual Review of Pharmacology and Toxicology | volume = 50 | issue = 1 | pages = 157–186 | date = January 2010 | pmid = 20055701 | doi = 10.1146/annurev.pharmtox.010909.105753 }}

See also

References

{{reflist}}

Further reading

{{refbegin}}

  • {{cite journal | vauthors = Takeda S, Kadowaki S, Haga T, Takaesu H, Mitaku S | title = Identification of G protein-coupled receptor genes from the human genome sequence | journal = FEBS Letters | volume = 520 | issue = 1-3 | pages = 97–101 | date = June 2002 | pmid = 12044878 | doi = 10.1016/S0014-5793(02)02775-8 | s2cid = 7116392 | doi-access = free }}

{{refend}}

{{G protein-coupled receptors}}

Category:G protein-coupled receptors

{{transmembranereceptor-stub}}