LRRFIP1
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
Leucine-rich repeat flightless-interacting protein 1 is a protein that in humans is encoded by the LRRFIP1 gene.{{cite journal | vauthors = Reed AL, Yamazaki H, Kaufman JD, Rubinstein Y, Murphy B, Johnson AC | title = Molecular cloning and characterization of a transcription regulator with homology to GC-binding factor | journal = J Biol Chem | volume = 273 | issue = 34 | pages = 21594–602 | date = Sep 1998 | pmid = 9705290 | doi = 10.1074/jbc.273.34.21594 | doi-access = free }}{{cite journal | vauthors = Liu YT, Yin HL | title = Identification of the binding partners for flightless I, A novel protein bridging the leucine-rich repeat and the gelsolin superfamilies | journal = J Biol Chem | volume = 273 | issue = 14 | pages = 7920–7 | date = May 1998 | pmid = 9525888 | doi = 10.1074/jbc.273.14.7920 | doi-access = free }}{{cite journal | vauthors = Suriano AR, Sanford AN, Kim N, Oh M, Kennedy S, Henderson MJ, Dietzmann K, Sullivan KE | title = GCF2/LRRFIP1 represses tumor necrosis factor alpha expression | journal = Mol Cell Biol | volume = 25 | issue = 20 | pages = 9073–81 | date = Oct 2005 | pmid = 16199883 | pmc = 1265793 | doi = 10.1128/MCB.25.20.9073-9081.2005 }}{{cite web | title = Entrez Gene: LRRFIP1 leucine rich repeat (in FLII) interacting protein 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9208}}
Interactions
LRRFIP1 has been shown to interact with FLII.{{cite journal | vauthors = Fong KS, de Couet HG | title = Novel proteins interacting with the leucine-rich repeat domain of human flightless-I identified by the yeast two-hybrid system | journal = Genomics | volume = 58 | issue = 2 | pages = 146–57 | date = Jun 1999 | pmid = 10366446 | doi = 10.1006/geno.1999.5817 }}
References
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Further reading
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- {{cite journal | vauthors = Wilson SA, Brown EC, Kingsman AJ, Kingsman SM | title = TRIP: a novel double stranded RNA binding protein which interacts with the leucine rich repeat of flightless I | journal = Nucleic Acids Res. | volume = 26 | issue = 15 | pages = 3460–7 | year = 1998 | pmid = 9671805 | pmc = 147727 | doi = 10.1093/nar/26.15.3460 }}
- {{cite journal | vauthors = Khachigian LM, Santiago FS, Rafty LA, Chan OL, Delbridge GJ, Bobik A, Collins T, Johnson AC | title = GC factor 2 represses platelet-derived growth factor A-chain gene transcription and is itself induced by arterial injury | journal = Circ. Res. | volume = 84 | issue = 11 | pages = 1258–67 | year = 1999 | pmid = 10364563 | doi = 10.1161/01.res.84.11.1258 | doi-access = free }}
- {{cite journal | vauthors = Fong KS, de Couet HG | title = Novel proteins interacting with the leucine-rich repeat domain of human flightless-I identified by the yeast two-hybrid system | journal = Genomics | volume = 58 | issue = 2 | pages = 146–57 | year = 1999 | pmid = 10366446 | doi = 10.1006/geno.1999.5817 }}
- {{cite journal | vauthors = Rikiyama T, Curtis J, Oikawa M, Zimonjic DB, Popescu N, Murphy BA, Wilson MA, Johnson AC | title = GCF2: expression and molecular analysis of repression | journal = Biochim. Biophys. Acta | volume = 1629 | issue = 1–3 | pages = 15–25 | year = 2003 | pmid = 14522076 | doi = 10.1016/s0167-4781(03)00156-8 | url = https://zenodo.org/record/1259889 }}
- {{cite journal | vauthors = Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP | title = Large-scale characterization of HeLa cell nuclear phosphoproteins | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 101 | issue = 33 | pages = 12130–5 | year = 2004 | pmid = 15302935 | pmc = 514446 | doi = 10.1073/pnas.0404720101 | bibcode = 2004PNAS..10112130B | doi-access = free }}
- {{cite journal | vauthors = Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP | title = A probability-based approach for high-throughput protein phosphorylation analysis and site localization | journal = Nat. Biotechnol. | volume = 24 | issue = 10 | pages = 1285–92 | year = 2006 | pmid = 16964243 | doi = 10.1038/nbt1240 | s2cid = 14294292 }}
- {{cite journal | vauthors = Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M | title = Global, in vivo, and site-specific phosphorylation dynamics in signaling networks | journal = Cell | volume = 127 | issue = 3 | pages = 635–48 | year = 2006 | pmid = 17081983 | doi = 10.1016/j.cell.2006.09.026 | s2cid = 7827573 | doi-access = free }}
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