LSB

• Liga Sudamericana de Básquetbol, South America's prime international basketball league
• Liga Superior de Baloncesto, Cuba's top basketball league

• Legal Services Board, independent body responsible for overseeing the regulation of lawyers in England and Wales
• Lending Standards Board, promote fair lending and increase consumer protection in the UK; by proactively monitoring and enforcing the Standards of Lending Practice.
• Lexington State Bank, a banking company based in Lexington, North Carolina
• Local services board (Ontario), local government in the Canadian province of Ontario
• Local Station Board, the elected governing body for each of the non-commercial, listener-supported Pacifica Radio stations in the United States.
• Lån & Spar Bank, a banking company based in Copenhagen, Denmark

• Lavelle School for the Blind, school in New York City
• London School Board, former local government and education
• Luxembourg School of Business, a business school in Luxembourg
• Lyceum of Subic Bay, a college in the Philippines

• Lauryl tryptose broth, a biological selective medium
• Lower sideband, a band of frequencies in radio communications
• Long spine board, a device for casualty lifting and spine trauma prehospital care
• Low-surface-brightness galaxy, in astronomy
• Lysergic acid 2-butyl amide, a psychoactive compound related to LSD

• Least significant bit, the bit with the lowest significance in a word
• Least significant byte, the lowest byte in a multi-byte number
• Linux Standard Base, a standardisation project for Linux distributions

• Lenguaje de Señas Bolivianas, Bolivian Sign Language
• Lutheran Service Book, hymnal for the Lutheran Church
• Legacy Standard Bible, revision of the NASB 1995 that uses Yahweh instead of LORD

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