Lambdapapillomavirus

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Lambdapapillomavirus is a genus of viruses in the family Papillomaviridae.{{cite journal |last1=Van Doorslaer |first1=K |last2=Chen |first2=Z |last3=Bernard |first3=HU |last4=Chan |first4=PKS |last5=DeSalle |first5=R |last6=Dillner |first6=J |last7=Forslund |first7=O |last8=Haga |first8=T |last9=McBride |first9=AA |last10=Villa |first10=LL |last11=Burk |first11=RD |last12=ICTV Report Consortium |title=ICTV Virus Taxonomy Profile: Papillomaviridae. |journal=The Journal of General Virology |date=August 2018 |volume=99 |issue=8 |pages=989–990 |doi=10.1099/jgv.0.001105 |pmid=29927370|pmc=6171710 }} Cats and dogs serve as natural hosts. There are five species in this genus. Diseases associated with this genus include mucosal and cutaneous lesions.{{cite web|title=Viral Zone|url=http://viralzone.expasy.org/all_by_species/548.html|publisher=ExPASy|accessdate=15 June 2015}}{{cite web |title=Virus Taxonomy: 2020 Release |url=https://ictv.global/taxonomy |publisher=International Committee on Taxonomy of Viruses (ICTV) |date=March 2021 |access-date=10 May 2021}}

Taxonomy

The following five species are assigned to the genus:

Structure

Viruses in Lambdapapillomavirus are non-enveloped, with icosahedral geometries, and T=7 symmetry. The diameter is around 52-55 nm. Genomes are circular, around 8kb in length.

Genus	Structure \|\| Symmetry	Capsid	Genomic arrangement	Genomic segmentation
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Lambdapapillomavirus	Icosahedral	T=7	Non-enveloped	Circular	Monopartite

Life cycle

Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear envelope breakdown.

Cats and dogs serve as the natural host. Transmission routes are contact.

Genus	Host details	Tissue tropism	Entry details	Release details	Replication site	Assembly site	Transmission
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Lambdapapillomavirus	Cats; dogs	Epithelial: mucous; epithelial: skin	Cell receptor endocytosis	Lysis	Nucleus	Nucleus	Contact

References

External links

[https://ictv.global/report/papillomaviridae ICTV Report Papillomaviridae]
[http://viralzone.expasy.org/all_by_species/548.html Viralzone: Lambdapapillomavirus]

Category:Papillomavirus

Category:Virus genera