Lawrence Hunter

Hunter completed his PhD at Yale University in 1989 with a thesis on Knowledge Acquisition Planning: Gaining Expertise Through Experience, on diagnosis of lung cancer from histological images using Case-based reasoning,{{Cite journal | last1 = Gibson | first1 = Todd A. | title = The Roots of Bioinformatics in ISMB | doi = 10.1371/journal.pcbi.1002679 | journal = PLOS Computational Biology | volume = 8 | issue = 8 | pages = e1002679 | year = 2012 | pmid = 22952443| pmc = 3431341| bibcode = 2012PLSCB...8E2679G | doi-access = free }} under the guidance of Roger Schank.{{cite thesis |degree=PhD |first=Lawrence E.|last=Hunter |title=Knowledge acquisition planning: Gaining expertise through experience |publisher=Yale University |date=1989 |author-link= Lawrence Hunter|hdl= 10079/bibid/9838922|oclc=24116492|id={{ProQuest|303852846}}}}

Faced with a choice between careers in the main applications of artificial intelligence---game programming and defense work—Hunter chose an emerging new discipline, bioinformatics. From 1989 to 2000, Hunter worked as a computer scientist and section chief for National Institutes of Health sections devoted to statistical and bioinformatic research. He was an adjunct faculty member at George Mason University from 1991 through 2000{{Citation needed|date=April 2018}} and an associate professor in the University of Colorado Denver School of Medicine from 2000 to 2008. He was promoted to professor in 2008.{{cite book |author=Hunter, Lawrence |title=The processes of life: an introduction to molecular biology |publisher=MIT Press |location=Cambridge, Massachusetts |year=2009 |isbn=978-0-262-01305-5 |author-link = Lawrence Hunter}}

In 1997, Hunter founded what has become the largest professional organization in computational biology and bioinformatics, the International Society for Computational Biology (ISCB).{{Cite journal

| title = Proceedings of the 6th International Conference on Intelligent Systems for Molecular Biology. Montreal, Quebec, Canada. June 28-July 1, 1998

| journal = Proceedings. International Conference on Intelligent Systems for Molecular Biology

| volume = 6

| pages = 1–223

| year = 1998

| pmid = 9867411

}}

Hunter was also a founder of three successful international conferences in bioinformatics, the International Conference on Intelligent Systems for Molecular Biology (ISMB) and the Pacific Symposium on Biocomputing (PSB){{Cite journal

| journal = Proceedings. International Conference on Intelligent Systems for Molecular Biology

| volume = 4

| pages = 1–262

| year = 1996

| pmid = 9005023

| title = Proceedings of the 4th International Conference on Intelligent Systems for Molecular Biology. ISMB-96.

}} and the Rocky Mountain Bioinformatics Conference.{{cite web|url=http://www.iscb.org/rocky09|title=Rocky 09 - Welcome!|website=Iscb.org|access-date=12 April 2018}} He is also a co-organizer of the biological visualization conference Vizbi.{{cite web|url=http://vizbi.org|title=VIZBI - Visualizing Biological Data|first=Sean|last=O'Donoghue|website=Vizbi.org|access-date=12 April 2018}} Hunter cofounded and was a member of the Board of Directors of the Molecular Mining Corporation from 1997 to 2003.

Hunter is a Fellow of the American College of Medical Informatics{{Citation needed|date=April 2018}}{{when|date=April 2018}} and the winner of the Association for the Advancement of Artificial Intelligence (AAAI) 2003 Engelmore Prize for Innovative Applications of Artificial Intelligence.{{Citation needed|date=April 2018}}

Hunter is credited with being one of the founders of the field of bioinformatics.{{Citation needed|date=April 2018}} Throughout his career Hunter has researched and directed research groups investigating the development and application of advanced computational techniques for biomedicine to high-throughput assays, particularly the application of statistical and knowledge-based techniques, in particular bio-ontologies,{{Cite journal|last1=Livingston|first1=Kevin M.|last2=Bada|first2=Michael|last3=Baumgartner|first3=William A.|last4=Hunter|first4=Lawrence E.|date=2015-04-23|title=KaBOB: ontology-based semantic integration of biomedical databases |journal=BMC Bioinformatics|volume=16|issue=1 |pages=126|doi=10.1186/s12859-015-0559-3|issn=1471-2105|pmc=4448321|pmid=25903923 |doi-access=free }} to the analysis of high-throughput data and of biomedical texts. He has proposed neurobiologically and evolutionarily informed computational models of cognition, and ethical issues related to computational bioscience. He has argued for expansion data science activities in biomedicine to include knowledge-based methods.{{Cite journal|last=Hunter|first=Lawrence E.|date=2017|title=Knowledge-based biomedical Data Science |journal=EPJ Data Science|volume=1|issue=1–2|pages=19–25|doi=10.3233/DS-170001|issn=2193-1127|pmc=6171523|pmid=30294517}}

He became an ISCB Fellow in 2010. Other awards and honors include Regent's Award for Scholarship and Technical Achievement 1994{{Citation needed|date=April 2018}} Meritorious Service Award, National Library of Medicine, 1991, 1992, 1993, 1994, 1995, 1996, 1997, 1998{{Citation needed|date=April 2018}} Excellence in Research Award, University of Colorado School of Medicine Department of Pharmacology, 2007{{Citation needed|date=April 2018}} Excellence in Teaching Award, University of Colorado School of Medicine Department of Preventive Medicine and Biometrics, 2004.{{Citation needed|date=April 2018}}

Selected publications include:

• {{Cite journal

| last1 = Rindflesch | first1 = T.

| last2 = Tanabe | first2 = L.

| last3 = Weinstein | first3 = J.

| last4 = Hunter | first4 = L.

| author-link4 = Lawrence Hunter

| title = EDGAR: Extraction of drugs, genes and relations from the biomedical literature

| journal = Pacific Symposium on Biocomputing

| pages = 517–528

| year = 2000

| pmid = 10902199

| pmc = 2709525

| doi = 10.1142/9789814447331_0049

| isbn = 978-981-02-4188-9

}}

• {{Cite journal | last1 = Schank | first1 = R. C. | last2 = Collins | first2 = G. C. | last3 = Hunter | first3 = L. E. | author-link3 = Lawrence Hunter| doi = 10.1017/S0140525X00051578 | title = Transcending inductive category formation in learning | journal = Behavioral and Brain Sciences | volume = 9 | issue = 4 | pages = 639 | year = 1986| s2cid = 144458369 }}
• {{Cite book | last1 = Rindflesch | first1 = T. C. | title = Proceedings of the sixth conference on Applied natural language processing - | last2 = Rajan | first2 = J. V. | last3 = Hunter | first3 = L. | author-link3 = Lawrence Hunter| doi = 10.3115/974147.974173 | pages = 188–195 | year = 2000 | chapter = Extracting molecular binding relationships from biomedical text | s2cid = 16166432 }}
• [https://books.google.com/books?id=5vo9zMJRnMwC&dq=Lawrence+Hunter&pg=PA41 Planning to learn] The Proceedings of the Twelfth Annual Conference of the Cognitive Science Society, Boston, MA., July 1990, pp. 26–34, Lawrence Erlbaum Associates, Hillsdale, NJ. in.{{cite book |author1=Leake, David B. |author2=Ram, Ashwin |title=Goal-driven learning |publisher=MIT Press |location=Cambridge, Massachusetts |year=1995 |isbn=978-0-262-18165-5 }}
• {{Cite book|author=Hunter, Lawrence |title=Artificial intelligence and molecular biology |publisher=AAAI Press |location=Menlo Park, Calif |year=1993 |isbn=978-0-262-58115-8}}
• {{Cite journal | last1 = Baumgartner | first1 = W. A. | last2 = Cohen | first2 = K. B. | last3 = Fox | first3 = L. M. | last4 = Acquaah-Mensah | first4 = G. | last5 = Hunter | first5 = L. | author-link5 = Lawrence Hunter| title = Manual curation is not sufficient for annotation of genomic databases | doi = 10.1093/bioinformatics/btm229 | journal = Bioinformatics | volume = 23 | issue = 13 | pages = i41–i48 | year = 2007 | pmid = 17646325| pmc =2516305 }}
• {{Cite journal | last1 = Hunter | first1 = L. | author-link1 = Lawrence Hunter| last2 = Lu | first2 = Z. | last3 = Firby | first3 = J. | last4 = Baumgartner Jr | first4 = W. A. | last5 = Johnson | first5 = H. L. | last6 = Ogren | first6 = P. V. | last7 = Cohen | first7 = K. B. | title = OpenDMAP: An open source, ontology-driven concept analysis engine, with applications to capturing knowledge regarding protein transport, protein interactions and cell-type-specific gene expression | doi = 10.1186/1471-2105-9-78 | journal = BMC Bioinformatics | volume = 9 | pages = 78 | year = 2008 | pmid = 18237434| pmc =2275248 | doi-access = free }}
• {{Cite journal | last1 = Leach | first1 = S. M. | last2 = Tipney | first2 = H. | last3 = Feng | first3 = W. | last4 = Baumgartner | first4 = W. A. | last5 = Kasliwal | first5 = P. | last6 = Schuyler | first6 = R. P. | last7 = Williams | first7 = T. | last8 = Spritz | first8 = R. A. | last9 = Hunter | first9 = L. | author-link9 = Lawrence Hunter| editor1-last = Miyano | editor1-first = Satoru | title = Biomedical Discovery Acceleration, with Applications to Craniofacial Development | doi = 10.1371/journal.pcbi.1000215 | journal = PLOS Computational Biology | volume = 5 | issue = 3 | pages = e1000215 | year = 2009 | pmid = 19325874| pmc =2653649 | bibcode = 2009PLSCB...5E0215L | doi-access = free }}
• Hunter, Lawrence (2009). The processes of life: an introduction to molecular biology. Cambridge, Massachusetts: MIT Press. {{ISBN|0-262-01305-3}}.

{{Reflist}}

{{s-start}}

{{s-bef|before=None}}

{{s-ttl|title=President of the
International Society for Computational Biology

|years=1997 – 2000}}

{{s-aft|after=Russ Altman}}

{{s-end}}

{{ISCB Fellows}}

{{Authority control}}

{{DEFAULTSORT:Hunter, Lawrence}}

Category:1961 births

Category:Living people

Category:Artificial intelligence researchers

Category:American bioinformaticians

Category:Fellows of the International Society for Computational Biology

Category:University of Colorado Denver faculty

Category:Yale University alumni