Leukocyte-promoting factor

{{Short description|Category of substances produced by neutrophils when they encounter a foreign antigen}}

Leukocyte-promoting factor, more commonly known as leukopoietin, is a category of substances produced by neutrophils when they encounter a foreign antigen. Leukopoietin stimulates the bone marrow to increase the rate of leukopoiesis in order to replace the neutrophils that will inevitably be lost when they begin to phagocytose the foreign antigens.{{cn|date=November 2021}}

Leukocyte-promoting factors include colony stimulating factors (CSFs) (produced by monocytes and T lymphocytes), interleukins (produced by monocytes, macrophages, and endothelial cells), prostaglandins, and lactoferrin.{{cite book | author = Ghai CL| title = A textbook of practical physiology | year = 2013 | publisher = Jaypee Bros. Medical Publishers | location = New Delhi | isbn = 9789350259320 | page=65 | edition = 8th | url = https://books.google.com/books?id=gH_rS8tuz8wC&dq=Leukocyte-promoting+factor&pg=PA65}}