Lipschütz ulcer

{{Infobox medical condition (new)

| name = Lipschütz ulcer

| synonyms =

| image = Lipschutz ulcer original image.jpg

| caption = One of the first published cases of Lipschütz ulcer

| pronounce =

| field =

| symptoms =

| complications =

| onset =

| duration =

| types =

| causes =

| risks =

| diagnosis =

| differential =

| prevention =

| treatment =

| medication =

| prognosis =

| frequency =

| deaths =

}}

Lipschütz ulcer, ulcus vulvae acutum or reactive non-sexually related acute genital ulcers ({{langx|en|acute ulceration of the vulva}}) is a rare disease characterized by painful genital ulcers, fever, and lymphadenopathy, occurring most commonly, but not exclusively, in adolescents and young women.{{Cite journal|last1=Vieira-Baptista|first1=Pedro|last2=Lima-Silva|first2=Joana|last3=Beires|first3=Jorge|last4=Martinez-de-Oliveira|first4=José|date=2016-03-01|title=Lipschütz ulcers: should we rethink this? An analysis of 33 cases|journal=European Journal of Obstetrics, Gynecology, and Reproductive Biology|volume=198|pages=149–152|doi=10.1016/j.ejogrb.2015.07.016|issn=1872-7654|pmid=26297242}} Previously, it was described as being more common in virgins.{{cite journal |vauthors=Török L, Domján K, Faragó E |title=Ulcus vulvae acutum |journal=Acta Dermatovenereologica Alpina, Pannonia et Adriatica |year=2000 |volume=9 |issue=1 |issn=1581-2979 |url=http://ibmi.mf.uni-lj.si/acta-apa/acta-apa-00-1/torok.html}} It is not a sexually transmitted infection, and is often misdiagnosed,{{cite journal |vauthors=Kluger N, Garcia C, Guillot B |title=[Lipschütz acute genital ulcer] |language=fr |journal=J Gynecol Obstet Biol Reprod (Paris) |volume=38 |issue=6 |pages=528–30 |date=October 2009 |pmid=19744804 |doi=10.1016/j.jgyn.2009.08.005}}{{WhoNamedIt|synd|2265|Lipschütz' ulcer}} Retrieved on 2009-12-04. sometimes as a symptom of Behçet's disease.{{cite book |chapter=Erkrankungen des weiblichen Genitales |year=2005 |title=Dermatologie und Venereologie |veditors=Braun-Falco O, Plewig G, Wolff HH, Burgdorf WH, Landthaler M |language=de |location=Berlin |publisher=Springer |pages=1030 |isbn=978-3-540-40525-2}}

Lipschütz ulcer is named after Benjamin Lipschütz, who first described it in 1912.{{cite journal |author=Lipschütz B |title=Über eine eigenartige Geschwürsform des weiblichen Genitales (Ulcus vulvae acutum) |language=de |journal=Arch Dermatol Res |volume=114 |issue=1 |pages=363–96 |date=October 1912 |doi=10.1007/BF01973166|s2cid=11890180 |url= https://scholar.archive.org/work/b6v6wnb2fzearlwbr4xq3gimle/access/ia_file/crossref-pre-1923-scholarly-works/10.1007%252Fbf01963479.zip/10.1007%252Fbf01973166.pdf }} The cause is still unknown, although it has been associated with several infectious causes, including paratyphoid fever, cytomegalovirus, Mycoplasma pneumoniae and Epstein–Barr virus infection{{cite journal |vauthors=Pelletier F, Aubin F, Puzenat E, etal |title=Lipschütz genital ulceration: a rare manifestation of paratyphoid fever |journal=Eur J Dermatol |volume=13 |issue=3 |pages=297–8 |year=2003 |pmid=12804994}}{{cite journal |vauthors=Martín JM, Godoy R, Calduch L, Villalon G, Jordá E |title=Lipschütz acute vulval ulcers associated with primary cytomegalovirus infection |journal=Pediatr Dermatol |volume=25 |issue=1 |pages=113–5 |year=2008 |pmid=18304169 |doi=10.1111/j.1525-1470.2007.00597.x|s2cid=23743938 }}{{Cite journal|last1=Vieira-Baptista|first1=Pedro|last2=Machado|first2=Luísa|last3=Costa|first3=Ana Rosa|last4=Beires|first4=Jorge|last5=Martinez-de-Oliveira|first5=José|date=2013-07-01|title=Mycoplasma pneumoniae: a rare cause of vulvar ulcers or an undiagnosed one?|journal=Journal of Lower Genital Tract Disease|volume=17|issue=3|pages=330–334|doi=10.1097/LGT.0b013e3182710896|issn=1526-0976|pmid=23486069|s2cid=145823}}