List of epidemics and pandemics

580 Dysentery Epidemic in Gaul

| data-sort-value="057500000"|15–100 million

| {{Cite journal|last1=Mordechai|first1=Lee|last2=Eisenberg|first2=Merle|last3=Newfield|first3=Timothy P.|last4=Izdebski|first4=Adam|last5=Kay|first5=Janet E.|last6=Poinar|first6=Hendrik|date=2019-12-17|title=The Justinianic Plague: An inconsequential pandemic?|journal=Proceedings of the National Academy of Sciences|language=en|volume=116|issue=51|pages=25546–25554|doi=10.1073/pnas.1903797116|issn=0027-8424|pmid=31792176|pmc=6926030|bibcode=2019PNAS..11625546M |doi-access=free}}{{Cite news|last=Tharoor|first=Ishaan|date=2010-10-26|title=Top 10 Terrible Epidemics - TIME|language=en-US|magazine=Time|url=https://content.time.com/time/specials/packages/article/0,28804,2027479_2027486_2027546,00.html|access-date=2020-12-29|issn=0040-781X|archive-date=2021-01-16|archive-url=https://web.archive.org/web/20210116214316/http://content.time.com/time/specials/packages/article/0,28804,2027479_2027486_2027546,00.html|url-status=live}}{{cite web|last1=Maugh|first1=Thomas|title=An Empire's Epidemic|url=https://www.ph.ucla.edu/epi/bioter/anempiresepidemic.html|access-date=20 March 2020|website=University of California, Los Angeles|archive-date=4 August 2002|archive-url=https://web.archive.org/web/20020804054553/https://www.ph.ucla.edu/epi/bioter/anempiresepidemic.html|url-status=live}}

| data-sort-value="0580"|580

| Gaul

| Dysentery or possibly smallpox

| data-sort-value="000000000"|450,000 (10% of the Gaul population)

| Gregory of Tours. A History of the Franks. Pantianos Classics, 1916

Roman Plague of 590 (part of first plague pandemic)

| data-sort-value="0590"|590

| Rome, Byzantine Empire

| data-sort-value="000000000"|Unknown

| {{cite web|url=http://www.ph.ucla.edu/epi/bioter/anempiresepidemic.html|title=An Empire's Epidemic|first=Ralph R.|last=Frerichs|website=Ph.ucla.edu|access-date=7 July 2018|archive-date=13 December 2008|archive-url=https://web.archive.org/web/20081213013158/http://www.ph.ucla.edu/EPI/bioter/anempiresepidemic.html|url-status=live}}

Plague of Sheroe (part of first plague pandemic)

| data-sort-value="0627"|627–628

| Bilad al-Sham

| data-sort-value="25001"|25,000+

Plague of Amwas (part of first plague pandemic)

| data-sort-value="0638"|638–639

| Byzantine Empire, West Asia, Africa

| data-sort-value="25001"|25,000+

| {{Cite journal|last=Turner|first=David|date=November 1990|title=The Politics of Despair: The Plague of 746–747 and Iconoclasm in the Byzantine Empire1|journal=Annual of the British School at Athens|language=en|volume=85|pages=419–434|doi=10.1017/S006824540001577X|s2cid=153709117 |issn=2045-2403}}

Plague of 664 (part of first plague pandemic)

| data-sort-value="0664"|664–689

| British Isles

| data-sort-value="000000000"|Unknown

| {{Cite journal|last=Maddicott|first=J. R.|date=1 August 1997|title=Plague in seventh century England|url=https://academic.oup.com/past/article/156/1/7/1438455|journal=Past & Present|language=en|issue=156|pages=7–54|doi=10.1093/past/156.1.7|issn=0031-2746|access-date=12 February 2020|archive-date=8 March 2021|archive-url=https://web.archive.org/web/20210308075049/https://academic.oup.com/past/article/156/1/7/1438455|url-status=live}}

Plague of 698–701 (part of first plague pandemic)

| data-sort-value="0746"|698–701

| Byzantine Empire, West Asia, Syria, Mesopotamia

735–737 Japanese smallpox epidemic

| data-sort-value="000000000"|Unknown

| {{Cite book |title=Plague and the end of Antiquity|editor-last=Little|editor-first=Lester K. |publisher=Cambridge University Press|year=2007 |isbn=978-0-521-84639-4|location=Cambridge|page=104}}

| data-sort-value="0735"|735–737

| Japan

| data-sort-value="02000000"|2 million (approx. {{frac|1|3}} of Japanese population)

| {{Cite journal |last=Suzuki |first=A. |year=2011 |title=Smallpox and the epidemiological heritage of modern Japan: Towards a total history |journal=Medical History |volume=55 |issue=3 |pages=313–318 |doi=10.1017/S0025727300005329 |pmc=3143877 |pmid=21792253}}{{Cite book |title=Encyclopedia of Plague and Pestilence: From Ancient Times to the Present |last=Kohn |first=George C. |publisher=Checkmark Books |year=2002 |isbn=978-0816048939 |location=Princeton, New Jersey |page=213}}

Plague of 746–747 (part of first plague pandemic)

| data-sort-value="0746"|746–747

| Byzantine Empire, West Asia, Africa

| data-sort-value="000000000"|Unknown

Black Death (start of the second plague pandemic)

| 1346–1353

| Eurasia and North Africa

| data-sort-value="075000000|75–200 million (30–60% of European population and 33% percent of the Middle Eastern population)

| {{Cite book |url=https://books.google.com/books?id=YiHHnV08ebkC&pg=PA21 |title=A pest in the land: new world epidemics in a global perspective |last=Austin Alchon |first=Suzanne |publisher=University of New Mexico Press |year=2003 |isbn=978-0-8263-2871-7 |page=21 |access-date=2016-04-22 |archive-url=https://web.archive.org/web/20190401101639/https://books.google.com/books?id=YiHHnV08ebkC&pg=PA21 |archive-date=2019-04-01 |url-status=live}}

Sweating sickness (multiple outbreaks)

| 1485–1551

| Britain (England) and later continental Europe

| Unknown, possibly an unknown species of hantavirus

| data-sort-value="10001"|10,000+

| {{cite journal |last1=Heyman |first1=Paul |last2=Simons |first2=Leopold |last3=Cochez |first3=Christel |title=Were the English Sweating Sickness and the Picardy Sweat Caused by Hantaviruses? |journal=Viruses |volume=6 |issue=1 |pages=151–171 |doi=10.3390/v6010151 |pmid=24402305 |pmc=3917436 |date=7 January 2014|doi-access=free }}

1489 Spain typhus epidemic

| 1489

| Spain

| data-sort-value="17000"|17,000

| {{cite web|title=Typhus, War, and Vaccines|url=http://www.historyofvaccines.org/content/blog/typhus-war-and-vaccines|website=historyofvaccines.org|date=16 March 2016|access-date=12 May 2020|archive-date=11 November 2020|archive-url=https://web.archive.org/web/20201111210627/https://www.historyofvaccines.org/content/blog/typhus-war-and-vaccines|url-status=dead}}

1510 influenza pandemic

| 1510

| Asia, North Africa, Europe

1520 Mexico smallpox epidemic

| data-sort-value="0"|Unknown, around 1% of those infected

| {{Cite journal|last1=Morens|first1=David|last2=North|first2=Michael|last3=Taubenberger|first3=Jeffrey|date=4 December 2011|title=Eyewitness accounts of the 1510 influenza pandemic in Europe|url= |journal=Lancet|volume=367|issue=9756|pages=1894–1895|pmid=21155080|doi=10.1016/s0140-6736(10)62204-0|pmc=3180818}}

| 1519–1520

| Mexico

Cocoliztli epidemic of 1545–1548

| data-sort-value="6500000" | 5–8 million (40% of population)

| {{Cite journal |title=Megadrought and Megadeath in 16th Century Mexico |date=April 8, 2002 |pmc = 2730237|last1 = Acuna-Soto|first1 = R.|last2 = Stahle|first2 = D. W.|last3 = Cleaveland|first3 = M. K.|last4 = Therrell|first4 = M. D.|journal = Emerging Infectious Diseases|volume = 8|issue = 4|pages = 360–362|doi = 10.3201/eid0804.010175|pmid = 11971767}}

| 1545–1548

| Mexico

| Possibly Salmonella enterica

| data-sort-value="010000000" | 5–15 million (80% of population)

| {{Cite web |url=https://www.newscientist.com/article/dn268-american-plague/ |title=American plague |date=December 19, 2000 |website=New Scientist |access-date=October 17, 2018 |archive-url=https://web.archive.org/web/20181017163205/https://www.newscientist.com/article/dn268-american-plague/ |archive-date=October 17, 2018 |url-status=live}}{{Cite journal |last1=Acuna-Soto |first1=R. |last2=Romero |first2=L. C. |last3=Maguire |first3=J. H. |year=2000 |title=Large epidemics of hemorrhagic fevers in Mexico 1545–1815 |journal=The American Journal of Tropical Medicine and Hygiene |volume=62 |issue=6 |pages=733–739 |doi=10.4269/ajtmh.2000.62.733 |pmid=11304065|doi-access=free }}{{Cite journal |last1=Acuna-Soto |first1=Rodolfo |last2=Stahle |first2=D. W. |last3=Cleaveland |first3=M. K. |last4=Therrell |first4=M. D. |year=2002 |title=Megadrought and Megadeath in 16th Century Mexico |journal=Emerging Infectious Diseases |volume=8 |issue=4 |pages=360–362 |doi=10.3201/eid0804.010175 |pmc=2730237 |pmid=11971767}}{{Cite journal |last1=Vågene |first1=Åshild J. |last2=Herbig |first2=Alexander |last3=Campana |first3=Michael G. |last4=Robles García |first4=Nelly M. |last5=Warinner |first5=Christina |last6=Sabin |first6=Susanna |last7=Spyrou |first7=Maria A. |last8=Andrades Valtueña |first8=Aida |last9=Huson |first9=Daniel |last10=Tuross |first10=Noreen |last11=Bos |first11=Kirsten I. |year=2018 |title=Salmonella enterica genomes from victims of a major sixteenth-century epidemic in Mexico |journal=Nature Ecology & Evolution |volume=2 |issue=3 |pages=520–528 |doi=10.1038/s41559-017-0446-6 |pmid=29335577 |last12=Krause |first12=Johannes|bibcode=2018NatEE...2..520V |s2cid=3358440 }}

1557 influenza pandemic

| 1557–1559

| Asia, Africa, Europe, and Americas

| 2.5–5 Million (10% of the infected)

1561 Chile smallpox epidemic

| 1561–1562

| Chile

| data-sort-value="0"|120,000–150,000 (20–25% of native population)

| Alonso de Góngora Marmolejo [http://www.cervantesvirtual.com/servlet/SirveObras/bameric/02582741011358306311291/p0000003.htm#I_34_ Historia de Chile desde su descubrimiento hasta el año 1575] {{Webarchive|url=https://web.archive.org/web/20150924114330/http://www.cervantesvirtual.com/servlet/SirveObras/bameric/02582741011358306311291/p0000003.htm#I_34_ |date=2015-09-24 }}. Cervantesvirtual.com. Retrieved on 2011-12-06.

1563 London plague (part of the second plague pandemic)

| 1563–1564

| London, England

Cocoliztli epidemic of 1576

| data-sort-value="20101" | 20,100+

| {{cite book|url=https://play.google.com/books/reader?id=kRMLAAAAIAAJ&printsec=frontcover&pg=GBS.PA309|title=A History of Epidemics in Britain|last=Creighton|first=Charles|publisher=Cambridge University Press|year=1891|location=Cambridge, UK|page=305|access-date=2020-05-08|archive-date=2021-12-25|archive-url=https://web.archive.org/web/20211225042823/https://play.google.com/books/reader?id=kRMLAAAAIAAJ&printsec=frontcover&pg=GBS.PA309|url-status=live}}

| 1576–1580

| Mexico

| Possibly Salmonella enterica

| data-sort-value="2250000" | 2–2.5 million (50% of population)

1582 Tenerife plague epidemic (part of the second plague pandemic)

| 1582–1583

| Tenerife, Spain

| data-sort-value="7000" | 5,000–9,000

|{{Cite web|url=https://www.museosdetenerife.org/assets/downloads/publication-f11acf7d04.pdf|title=Plague. The fourth horseman – Historic epidemics and their impact in Tenerife|language=es|page=28|access-date=15 May 2020|archive-date=25 February 2020|archive-url=https://web.archive.org/web/20200225131436/https://www.museosdetenerife.org/assets/downloads/publication-f11acf7d04.pdf|url-status=live}}

1592–1596 Seneca nation measles epidemic

| 1592–1596

| Seneca nation, North America

| data-sort-value="0"|Unknown

| {{Cite web|url=http://www.kporterfield.com/aicttw/articles/disease.html|archive-url=https://web.archive.org/web/20150214060648/http://www.kporterfield.com/aicttw/articles/disease.html|url-status=dead|title=American Indian Epidemics|archive-date=February 14, 2015}}

1592–1593 Malta plague epidemic (part of the second plague pandemic)

| 1592–1593

| Malta

| data-sort-value="000003000" | 3,000

| {{cite news |title=Our Heritage Saved: St Roque Chapel |url=https://www.independent.com.mt/articles/2007-05-30/local-news/Our-Heritage-Saved:-St-Roque-Chapel-174165 |work=The Malta Independent |date=30 May 2007 |archive-url=https://web.archive.org/web/20200313042952/https://www.independent.com.mt/articles/2007-05-30/local-news/Our-Heritage-Saved:-St-Roque-Chapel-174165 |archive-date=13 March 2020}}

1592–1593 London plague (part of the second plague pandemic)

| 1592–1593

| London, England

| data-sort-value="000019901" | 19,900+

| {{cite book |last=Creighton |first=Charles |author-link=Charles Creighton (physician) |date=November 1891 |title=A History of Epidemics in Britain: From A.D 664 to the Extinction of Plague |url=https://archive.org/stream/historyofepidemi01crei#page/350/mode/2up |location=Cambridge, UK |publisher=Cambridge University Press |pages=353–354}}

1596–1602 Spain plague epidemic (part of the second plague pandemic)

| 1596–1602

| Spain

| data-sort-value="650000"| 600,000–700,000

| {{Cite web |url=http://libro.uca.edu/payne1/payne15.htm |title=A History of Spain |access-date=16 November 2014 |archive-url=https://web.archive.org/web/20170327015606/http://libro.uca.edu/payne1/payne15.htm |archive-date=27 March 2017 |url-status=live}}

1600–1650 South America malaria epidemic

| 1600–1650

| South America

| data-sort-value="0"|Unknown

|{{Citation needed|date=January 2021}}

1603 London plague (part of the second plague pandemic)

| 1603

| London, England

| 40,000

|{{Cite web|url=https://us.macmillan.com/books/9781466864504|title=The Death of Queen Elizabeth I, the Return of the Black Plague, the Rise of Shakespeare, Piracy, Witchcraft, and the Birth of the Stuart Era|access-date=11 May 2020|archive-date=12 July 2021|archive-url=https://web.archive.org/web/20210712225740/https://us.macmillan.com/books/9781466864504|url-status=live}}{{Cite web|url=http://www.shakespeare-online.com/biography/londondisease.html|title=Worst Diseases in Shakespeare's London|access-date=11 May 2020|archive-date=8 May 2020|archive-url=https://web.archive.org/web/20200508114250/http://www.shakespeare-online.com/biography/londondisease.html|url-status=live}}Bell, Walter George (1951). Belinda Hollyer (ed.). The great Plague in London (folio society ed.). Folio society by arrangement with Random House. pp. 3–5

1616 New England infections epidemic

| 1616–1620

| Southern New England, British North America, especially the Wampanoag people

| Unknown, possibly leptospirosis with Weil syndrome. Classic explanations include yellow fever, bubonic plague, influenza, smallpox, chickenpox, typhus, and syndemic infection of hepatitis B and hepatitis D

| data-sort-value="0"|1,143,000–3,429,000 (estimated 30–90% of population)

|{{Cite journal |last1=Marr |first1=John S. |last2=Cathey |first2=John T. |year=2010 |title=New Hypothesis for Cause of Epidemic among Native Americans, New England, 1616–1619 |journal=Emerging Infectious Diseases |volume=16 |issue=2 |pages=281–286 |doi=10.3201/eid1602.090276 |pmc=2957993 |pmid=20113559}}{{Cite web |url=https://www.smithsonianmag.com/history/native-intelligence-109314481/ |title=Native intelligence |last=Mann |first=Charles C. |date=December 2005 |access-date=2018-10-17 |archive-url=https://web.archive.org/web/20181123170227/https://www.smithsonianmag.com/history/native-intelligence-109314481/ |archive-date=2018-11-23 |url-status=live}}

1629–1631 Italian plague (part of the second plague pandemic)

| 1629–1631

| Italy

| data-sort-value="1000000" | 1 million

| {{Cite book |url=https://archive.org/details/epidemicspandemi0000hays |title=Epidemics and pandemics their impacts on human history |last=Hays |first=J. N. |date=2005 |publisher=ABC-CLIO |isbn=978-1851096589 |location=Santa Barbara, CA|page=[https://archive.org/details/epidemicspandemi0000hays/page/103 103] |url-access=registration}}

1632–1635 Augsburg plague epidemic (part of the second plague pandemic)

| 1632–1635

| Augsburg, Germany

Massachusetts smallpox epidemic

| 13,712

| {{Cite book|last1=Eckert|first1=Edward-A.|url=https://www.persee.fr/doc/adh_0066-2062_1978_num_1978_1_1378|title=Annales de Démographie Historique|page=55|date=1978|volume=1978|issue=1|doi=10.3406/adh.1978.1378|access-date=14 May 2020|archive-date=27 November 2020|archive-url=https://web.archive.org/web/20201127202244/https://www.persee.fr/doc/adh_0066-2062_1978_num_1978_1_1378|url-status=live}}

| 1633–1634

| Massachusetts Bay Colony, Thirteen Colonies

| 1,000

| {{Cite web|url=https://www.usdeadlyevents.com/1633-34-smallpox-epidemic-new-england-natives-plymouth-colonists-ma-1000|title=1633–34 — Smallpox Epidemic, New England Natives, Plymouth Colonists, MA –>1000|website=usdeadlyevents.com|date=January 1632|access-date=13 May 2020|archive-date=8 September 2018|archive-url=https://web.archive.org/web/20180908083220/https://www.usdeadlyevents.com/1633-34-smallpox-epidemic-new-england-natives-plymouth-colonists-ma-1000|url-status=live}}

1634–1640 Wyandot people epidemic

| 1634–1640

| Wyandot people, North America

| Smallpox and Influenza

| data-sort-value="20000"|15,000–25,000

|{{cite book |last1=Johansen |first1=Bruce E. |title=American Indian Culture: From Counting Coup to Wampum [2 volumes]: From Counting Coup to Wampum |date=2015 |publisher=ABC-CLIO |isbn=978-1-4408-2874-4 |page=88 |url=https://books.google.com/books?id=mw-FCgAAQBAJ&q=wyandot+people++smallpox+1630&pg=PA88 |access-date=12 February 2020 |language=en |archive-date=6 January 2024 |archive-url=https://web.archive.org/web/20240106083412/https://books.google.com/books?id=mw-FCgAAQBAJ&q=wyandot+people++smallpox+1630&pg=PA88 |url-status=live }}

1637 London plague epidemic (part of the second plague pandemic)

| 1636–1637

| London and Westminster, England

| 10,400

|{{cite journal |last1=Newman |first1=Kira L. S.|title=Shutt up: bubonic plague and quarantine in early modern England|journal=Journal of Social History|date=2012|volume=45|issue=3|pages=809–834|doi=10.1093/jsh/shr114|jstor=41678910|pmid=22611587|s2cid=24952354|issn=0022-4529}}

Great Plague in the late Ming dynasty (part of the second plague pandemic)

| 1633–1644

| China

| data-sort-value="200000"|200,000+

| {{Cite journal|last=Ch'iu|first=Chung-lin|date=|title=The Epidemics in Ming Beijing and the Responses from the Empire's Public Health System|url=http://www.ihp.sinica.edu.tw/~bihp/75/75.2/chiu.htm|journal=中央研究院歷史語言研究所集刊|language=zh|volume=|pages=331–388|via=|access-date=2021-01-18|archive-date=2021-01-02|archive-url=https://web.archive.org/web/20210102130336/http://www.ihp.sinica.edu.tw/~bihp/75/75.2/chiu.htm|url-status=live}}{{Cite book |url=https://books.google.com/books?id=YuMcHWWbXqMC&pg=PA163 |title=The Confusions of Pleasure: Commerce and Culture in Ming China |last=Timothy Brook |publisher=University of California Press |year=1999 |isbn=978-0-520-22154-3 |page=163 |access-date=31 March 2011}}

Great Plague of Seville (part of the second plague pandemic)

| 1647–1652

| Spain

| 500,000

| [http://libro.uca.edu/payne1/payne15.htm Stanley G. Payne: A History of Spain and Portugal Volume 1, Ch 15 The Seventeenth-Century Decline] {{Webarchive|url=https://web.archive.org/web/20170327015606/http://libro.uca.edu/payne1/payne15.htm |date=2017-03-27 }} THE LIBRARY OF IBERIAN RESOURCES ONLINE, accessed 26 May 2020

1648 Central America yellow fever epidemic

| 1648

| Central America

| data-sort-value="0"|Unknown

| {{cite journal |last1=Rogers |first1=D.J. |last2=Wilson |first2=A.J. |last3=Hay |first3=S.I. |last4=Graham |first4=A.J. |title=The Global Distribution of Yellow Fever and Dengue |journal=Advances in Parasitology |date=2006 |volume=62 |pages=181–220 |doi=10.1016/S0065-308X(05)62006-4 |pmid=16647971 |pmc=3164798 |issn=0065-308X|isbn=9780120317622}}

Naples Plague (part of the second plague pandemic)

| 1656–1658

| Italy

| data-sort-value="1250000"|1,250,000

| {{cite journal |last1=Scasciamacchia |first1=Silvia |last2=Serrecchia |first2=Luigina |last3=Giangrossi |first3=Luigi |last4=Garofolo |first4=Giuliano |last5=Balestrucci |first5=Antonio |last6=Sammartino |first6=Gilberto |last7=Fasanella |first7=Antonio |title=Plague Epidemic in the Kingdom of Naples, 1656–1658 |journal=Emerging Infectious Diseases |volume=18 |issue=1 |pages=186–188 |doi=10.3201/eid1801.110597 |pmid=22260781 |pmc=3310102 |language=en-us|year=2012}}

1663–1664 Amsterdam plague epidemic (part of the second plague pandemic)

| 1663–1664

| Amsterdam, Netherlands

| 24,148

|{{Cite web|url=https://www.amsterdam.nl/stadsarchief/stukken/rampen/pest|title=De pest|language=nl|date=23 April 2019|access-date=13 May 2020|archive-date=11 April 2020|archive-url=https://web.archive.org/web/20200411093301/https://www.amsterdam.nl/stadsarchief/stukken/rampen/pest/|url-status=live}}

Great Plague of London (part of the second plague pandemic)

| 1665–1666

| England

| data-sort-value="000100000" | 100,000

| {{Cite web |url=http://www.britainexpress.com/History/plague.htm |title=UK travel and heritage – Britain Express UK travel guide |last=Ross |first=David |website=The London Plague of 1665 |access-date=14 July 2011 |archive-url=https://web.archive.org/web/20190526192602/https://www.britainexpress.com/History/plague.htm |archive-date=26 May 2019 |url-status=live}}{{Cite web |url=http://www.nationalarchives.gov.uk/education/resources/great-plague/ |title=Great Plague of 1665–1666 – The National Archives |last=Archives |first=The National |access-date=4 July 2016 |archive-url=https://web.archive.org/web/20160428020939/http://www.nationalarchives.gov.uk/education/resources/great-plague/ |archive-date=28 April 2016 |url-status=live}}

1668 France plague (part of the second plague pandemic)

| 1668

| France

| 40,000

|{{cite journal |last1=Jones |first1=Colin |title=Plague and Its Metaphors in Early Modern France |journal=Representations |date=1996 |volume=53 |issue=53 |pages=97–127 |doi=10.2307/2928672 |issn=0734-6018|jstor=2928672}}

1675–1676 Malta plague epidemic (part of the second plague pandemic)

| 1675–1676

| Malta

| data-sort-value="000011300" | 11,300

| {{cite news |last1=Grima |first1=Noel |title=The 1676 plague in Malta |url=http://www.independent.com.mt/articles/2017-06-19/newspaper-lifestyleculture/The-1676-plague-in-Malta-6736175628 |work=The Malta Independent |date=19 June 2017 |archive-url=https://web.archive.org/web/20171112063500/http://www.independent.com.mt/articles/2017-06-19/newspaper-lifestyleculture/The-1676-plague-in-Malta-6736175628 |archive-date=12 November 2017}}

1676–1685 Spain plague (part of the second plague pandemic)

| 1676–1685

| Spain

| Massachusetts Bay Colony, British North America

| data-sort-value="0"|Unknown

| {{cite book |last1=Casey |first1=James |title=Early Modern Spain: A Social History |date=1999 |publisher=Psychology Press |isbn=978-0-415-13813-0 |page=37 |url=https://books.google.com/books?id=mZJ8RnDhkgwC&q=plague+spain+1676&pg=PA37 |access-date=12 February 2020 |language=en |archive-date=6 January 2024 |archive-url=https://web.archive.org/web/20240106083413/https://books.google.com/books?id=mZJ8RnDhkgwC&q=plague+spain+1676&pg=PA37#v=snippet&q=plague%20spain%201676&f=false |url-status=live }}

1677–1678 Boston smallpox epidemic

| 1677–1678

| data-sort-value="875" | 750–1,000

| {{Cite web|url=https://www.usdeadlyevents.com/1677-1678-smallpox-epidemic-massachusetts-bay-colony-esp-boston-vic-750-1000|title=1677–1678 — Smallpox Epidemic, Massachusetts Bay Colony, esp. Boston & vic. –750-1,000|website=usdeadlyevents|date=January 1676|access-date=17 May 2020|archive-date=8 March 2021|archive-url=https://web.archive.org/web/20210308180625/https://www.usdeadlyevents.com/1677-1678-smallpox-epidemic-massachusetts-bay-colony-esp-boston-vic-750-1000/|url-status=live}}

Great Plague of Vienna (part of the second plague pandemic)

| 1679

| Vienna, Austria

| 76,000

| {{cite EB1911 |wstitle=Plague |volume=21 |page=696 |first=Joseph Frank |last=Payne}}

1681 Prague plague epidemic (part of the second plague pandemic)

| 1681

| Prague, Czech Kingdom

| 83,000

| {{Cite web|url=https://www.britannica.com/science/plague/History|title=Plague|website=britannica|access-date=14 May 2020|archive-date=16 January 2020|archive-url=https://web.archive.org/web/20200116154728/https://www.britannica.com/science/plague/History|url-status=live}}

1687 South Africa influenza outbreak

| 1687

| South Africa

| Unknown, possibly influenza

| data-sort-value="0"|Unknown

| History of South Africa 1486–1691, George McCall Theal, London, pub. Swan Sonnenschein, 1888. p. 332 "Towards the beginning of the winter of 1687 the colony was visited by a destructive disease, a kind of fever which carried off many of the inhabitants. The natives suffered very..."

1693 Boston yellow fever epidemic

| 1693

| Boston, Massachusetts Bay Colony, British North America

| data-sort-value="3100"|3,100+

| {{Cite web|url=https://www.usdeadlyevents.com/1693-june-17-start-yellow-fever-boston-british-fleet-arrival-from-martinique|title=1693 — June 17 start, Yellow Fever, Boston, British fleet arrival from Martinique[1]—<10?|date=17 June 1693|access-date=12 May 2020|archive-date=12 July 2021|archive-url=https://web.archive.org/web/20210712225707/https://www.usdeadlyevents.com/1693-june-17-start-yellow-fever-boston-british-fleet-arrival-from-martinique1/|url-status=live}}

1699 Charleston and Philadelphia yellow fever epidemic

| 1699

| Charleston and Philadelphia, British North America

| data-sort-value="520"|520 (300 in Charleston, 220 in Philadelphia)

| {{Cite web|url=https://www.usdeadlyevents.com/1699-yellow-fever-epidemics-charleston-sc170-311-philadelphia-220-390-531|title=1699 — Yellow Fever Epidemics Charleston, SC(170–311); Philadelphia (220) –390 – 531|date=January 1699|access-date=12 May 2020|archive-date=8 March 2021|archive-url=https://web.archive.org/web/20210308200722/https://www.usdeadlyevents.com/1699-yellow-fever-epidemics-charleston-sc170-311-philadelphia-220-390-531/|url-status=live}}

1702 New York City yellow fever epidemic

| 1702

| New York City, British North America

| 500

| {{Cite web|url=https://www.usdeadlyevents.com/1702-summer-to-late-fall-yellow-fever-epidemic-new-york-city-ny-500-570|title=1702 — Summer to late Fall, Yellow Fever Epidemic, New York City, NY −500-570|date=June 1702|access-date=12 May 2020|archive-date=8 March 2021|archive-url=https://web.archive.org/web/20210308162546/https://www.usdeadlyevents.com/1702-summer-to-late-fall-yellow-fever-epidemic-new-york-city-ny-500-570/|url-status=live}}

1702–1703 St. Lawrence Valley smallpox epidemic

| 1702–1703

| New France, Canada

1707–1708 Iceland smallpox epidemic

| 1,300

| {{Cite journal |last=Desjardins |first=Bertrand |year=1996 |title=Demographic Aspects of the 1702–1703 Smallpox Epidemic in the St. Lawrence Valley |journal=Canadian Studies in Population |volume=23 |issue=1 |pages=49–67 |doi=10.25336/P6459C|doi-access=free }}

| 1707–1709

| Iceland

| data-sort-value="18001" | 18,000+ (36% of population)

| {{Cite book |url=https://archive.org/details/epidemicspandemi0000hays |title=Epidemics and pandemics: their impacts on human history |last=J. N. Hays |publisher=ABC-CLIO |year=2005 |isbn=978-1-85109-658-9 |access-date=29 March 2011 |url-access=registration|page=131}}

Great Northern War plague outbreak (part of the second plague pandemic)

| 1710–1712

| Denmark, Sweden, Lithuania

| data-sort-value="164000" | 164,000

| {{cite book|last=Sticker|first=Georg|title=Die Pest|series=Abhandlungen aus der Seuchengeschichte und Seuchenlehre|volume=1|publisher=A. Töpelmann (vormals J. Ricker)|location=Gießen|year=1908|url=https://archive.org/details/abhandlungenausd01stic |page=213}}{{cite web|last1=Kroll|first1=Stefan|last2=Grabinsky|first2=Anne|title=Städtesystem und Urbanisierung im Ostseeraum in der Neuzeit – Historisches Informationssystem und Analyse von Demografie, Wirtschaft und Baukultur im 17. und 18. Jahrhundert. B: Komplexe Historische Informationssysteme. B2: Der letzte Ausbruch der Pest im Ostseeraum zu Beginn des 18. Jahrhunderts. Chronologie des Seuchenzugs und Bestandsaufnahme überlieferter Sterbeziffern. Karte|url=https://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Karte.html|publisher=University of Rostock|access-date=2012-08-14|archive-date=2007-07-03|archive-url=https://web.archive.org/web/20070703093729/http://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Karte.html|url-status=dead}}
Specific sections: [https://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Danzig.html Danzig] {{Webarchive|url=https://web.archive.org/web/20070703094255/http://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Danzig.html |date=2007-07-03 }}; [https://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/K%C3%B6nigsberg.html Königsberg] {{Webarchive|url=https://web.archive.org/web/20070703094245/http://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/K%C3%B6nigsberg.html |date=2007-07-03 }}; [https://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Stettin.html Stettin] {{Webarchive|url=https://web.archive.org/web/20070703094226/http://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Stettin.html |date=2007-07-03 }}; [https://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Memel.html Memel] {{Webarchive|url=https://web.archive.org/web/20070703094352/http://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Memel.html |date=2007-07-03 }}; [https://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Tilsit.html Tilsit] {{Webarchive|url=https://web.archive.org/web/20070703093928/http://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Tilsit.html |date=2007-07-03 }}; [https://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Narva.html Narva] {{Webarchive|url=https://web.archive.org/web/20070703093952/http://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Narva.html |date=2007-07-03 }}; [https://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Stargard.html Stargard] {{Webarchive|url=https://web.archive.org/web/20070703094305/http://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Stargard.html |date=2007-07-03 }}; [https://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Riga.html Riga] {{Webarchive|url=https://web.archive.org/web/20070703094330/http://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Riga.html |date=2007-07-03 }}; [https://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Pernau.html Pernau] {{Webarchive|url=https://web.archive.org/web/20070703094035/http://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Pernau.html |date=2007-07-03 }}; [https://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Reval.html Reval] {{Webarchive|url=https://web.archive.org/web/20070703093830/http://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Reval.html |date=2007-07-03 }}; [https://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Stralsund.html Stralsund] {{Webarchive|url=https://web.archive.org/web/20070703093903/http://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Stralsund.html |date=2007-07-03 }}; [https://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Stockholm.html Stockholm] {{Webarchive|url=https://web.archive.org/web/20070703094053/http://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Stockholm.html |date=2007-07-03 }}; [https://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Visby.html Visby] {{Webarchive|url=https://web.archive.org/web/20070703093753/http://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Visby.html |date=2007-07-03 }}; [https://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Linkoeping.html Linköping] {{Webarchive|url=https://web.archive.org/web/20070703094213/http://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Linkoeping.html |date=2007-07-03 }}; [https://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Joenkoeping.html Jönköping] {{Webarchive|url=https://web.archive.org/web/20070703094314/http://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Joenkoeping.html |date=2007-07-03 }}; [https://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Ystad.html Ystad] {{Webarchive|url=https://web.archive.org/web/20070703094013/http://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Ystad.html |date=2007-07-03 }}; [https://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Malmoe.html Malmö] {{Webarchive|url=https://web.archive.org/web/20070703094157/http://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Malmoe.html |date=2007-07-03 }}; [https://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Helsingoer.html Helsingør] {{Webarchive|url=https://web.archive.org/web/20070703093941/http://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Helsingoer.html |date=2007-07-03 }}; [https://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Kopenhagen.html Kopenhagen] {{Webarchive|url=https://web.archive.org/web/20070703094108/http://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Kopenhagen.html |date=2007-07-03 }}; [https://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Hamburg.html Hamburg] {{Webarchive|url=https://web.archive.org/web/20070703094144/http://www.phf.uni-rostock.de/imd/Forschung/HomeMare2/Seuchenzug/Staedte/Hamburg.html |date=2007-07-03 }}

1713–1715 North America measles epidemic

| 1713–1715

| Thirteen Colonies and New France, Canada

| data-sort-value="0"|Unknown

|{{cite journal |last1=Morens |first1=David M. |title=The Past Is Never Dead – Measles Epidemic, Boston, Massachusetts, 1713 |journal=Emerging Infectious Diseases |volume=21 |issue=7 |pages=1257–1260 |doi=10.3201/eid2107.150397 |pmid=26277799 |pmc=4480406 |language=en-us|year=2015}}{{Cite journal |last1=Mazan |first1=Ryan |last2=Gagnon |first2=Alain |last3=Desjardins |first3=Bertrand |year=2009 |title=The Measles Epidemic of 1714–1715 in New France |journal=Canadian Studies in Population |volume=36 |issue=3–4 |pages=295–323 |doi=10.25336/P63P5Q|doi-access=free }}

Great Plague of Marseille (part of the second plague pandemic)

| 1720–1722

| France

1721 Boston smallpox outbreak

| data-sort-value="100001" | 100,000+

| {{Cite journal |last=Devaux |first=Christian A. |year=2013 |title=Small oversights that led to the Great Plague of Marseille (1720–1723): Lessons from the past |journal=Infection, Genetics and Evolution |volume=14 |pages=169–185 |doi=10.1016/j.meegid.2012.11.016 |pmid=23246639|bibcode=2013InfGE..14..169D }}

| 1721–1722

| Massachusetts Bay Colony

| 844

| {{Cite web |url=http://www.todayinsci.com/B/Boylston_Zabdiel/Boylston_Zabdiel.htm |title=Zabdiel Boylston and inoculation |access-date=16 November 2014 |archive-url=https://web.archive.org/web/20150905143618/http://www.todayinsci.com/B/Boylston_Zabdiel/Boylston_Zabdiel.htm |archive-date=5 September 2015 |url-status=live}}

1730 Cádiz yellow fever epidemic

| 1730

| Cádiz, Spain

| 2,200

| {{Cite news|url=https://www.npr.org/sections/goatsandsoda/2016/08/28/491471697/yellow-fever-timeline-the-history-of-a-long-misunderstood-disease|title=Yellow Fever Timeline: The History Of A Long Misunderstood Disease|newspaper=NPR|date=28 August 2016|access-date=12 May 2020|last1=Brink|first1=Susan|archive-date=28 May 2020|archive-url=https://web.archive.org/web/20200528200648/https://www.npr.org/sections/goatsandsoda/2016/08/28/491471697/yellow-fever-timeline-the-history-of-a-long-misunderstood-disease|url-status=live}}

1732–1733 Thirteen Colonies influenza epidemic

| 1732–1733

| Thirteen Colonies

| data-sort-value="0"|Unknown

| {{Cite web |url=http://www.ambrosevideo.com/items.cfm?id=1071 |title=Ambrosevideo.com |access-date=2011-03-27 |archive-url=https://web.archive.org/web/20160417075306/http://www.ambrosevideo.com/items.cfm?id=1071 |archive-date=2016-04-17 |url-status=live}}

1733 New France smallpox epidemic

| 1733

| New France, Canada

| New England, Province of New York, Province of New Jersey, British North America

| data-sort-value="0"|Unknown

| {{Cite journal |last1=Gagnon |first1=Alain |last2=Mazan |first2=Ryan |year=2009 |title=Does exposure to infectious diseases in infancy affect old-age mortality? Evidence from a pre-industrial population |journal=Social Science & Medicine |volume=68 |issue=9 |pages=1609–1616 |doi=10.1016/j.socscimed.2009.02.008 |pmid=19269727}}

1735–1741 diphtheria epidemic

| 1735–1741

| Diphtheria

| 20,000

| {{Cite book|last=Purvis|first=Thomas L.|url=https://books.google.com/books?id=BZRJSx3uMYEC&q=1687+thirteen+colonies+++measles&pg=PA173|title=Colonial America To 1763|page=173|date=2014|publisher=Infobase|isbn=9781438107998|access-date=17 May 2020|archive-date=6 January 2024|archive-url=https://web.archive.org/web/20240106083406/https://books.google.com/books?id=BZRJSx3uMYEC&q=1687+thirteen+colonies+++measles&pg=PA173#v=snippet&q=1687%20thirteen%20colonies%20%20%20measles&f=false|url-status=live}}

Great Plague of 1738 (part of the second plague pandemic)

| 1738

| Balkans

1738–1739 North Carolina smallpox epidemic

| data-sort-value="50000" | 50,000

| {{cite web|url=http://www.genealogy.ro/cont/20c.htm|title=Banat's historical chronology for the last millennium- XVIII Century|website=www.genealogy.ro|publisher=Genealogy RO Group|access-date=26 May 2020|archive-date=4 June 2002|archive-url=https://web.archive.org/web/20020604232916/http://www.genealogy.ro/cont/20c.htm|url-status=live}}

| 1738–1739

| Province of Carolina, Thirteen Colonies

| data-sort-value="10,000" | 7,700–11,700

| {{Cite web|url=https://www.usdeadlyevents.com/1738-39-smallpox-catawba-ncsc-and-cherokee-natives-nc-7700-11700|title=1738–39 — Smallpox, Catawba (NC/SC) and Cherokee Natives (NC) –7,700–11,700|website=usdeadlyevents.com|date=January 1738|access-date=13 May 2020|archive-date=8 March 2021|archive-url=https://web.archive.org/web/20210308221130/https://www.usdeadlyevents.com/1738-39-smallpox-catawba-ncsc-and-cherokee-natives-nc-7700-11700/|url-status=live}}

1741 Cartagena yellow fever epidemic

| 1741

| Cartagena, Colombia

| data-sort-value="20,000" | 20,000

| {{Cite web|url=https://jdc.jefferson.edu/cgi/viewcontent.cgi?referer=https://www.ecosia.org/&httpsredir=1&article=1004&context=yellow_fever_symposium|title=The Early History of Yellow Fever|publisher=Thomas Jefferson University|page=3|website=jdc.jefferson.edu|date=September 2009|access-date=16 May 2020|archive-date=6 January 2024|archive-url=https://web.archive.org/web/20240106083407/https://jdc.jefferson.edu/cgi/viewcontent.cgi?referer=https://www.ecosia.org/&httpsredir=1&article=1004&context=yellow_fever_symposium|url-status=live}}

1743 Sicily plague epidemic (part of the second plague pandemic)

| 1743

| Messina, Sicily, Italy

| data-sort-value="45,000" | 40,000–50,000

| {{cite journal |last1=Tognotti |first1=Eugenia |title=Lessons from the History of Quarantine, from Plague to Influenza A|journal=Emerging Infectious Diseases |date=February 2013 |volume=19 |issue=2 |pages=254–259 |doi=10.3201/eid1902.120312 |pmid=23343512 |pmc=3559034 |language=en-us}}{{cite journal |last1=Wyman|first1=Walter|title=The North American Review|journal=The Black Plague|date=April 1897|volume=164|issue=485|page=442|publisher=University of Northern Iowa|jstor=25118799}}

1759 North America measles outbreak

| 1759

| North America

| data-sort-value="0"|Unknown

| {{cite book |last1=LeMay |first1=Michael C. |title=Global Pandemic Threats: A Reference Handbook: A Reference Handbook |date=2016 |publisher=ABC-CLIO |isbn=978-1-4408-4283-2 |page=227 |url=https://books.google.com/books?id=_UzODAAAQBAJ&q=1759++measles++north++america&pg=PA227 |access-date=12 February 2020 |language=en |archive-date=6 January 2024 |archive-url=https://web.archive.org/web/20240106083406/https://books.google.com/books?id=_UzODAAAQBAJ&q=1759++measles++north++america&pg=PA227 |url-status=live }}

1760 Charleston smallpox epidemic

| 1760

| Charleston, British North America

| data-sort-value="800" | 730–940

| {{cite journal |last1=Krebsbach |first1=Suzanne |title=The Great Charlestown Smallpox Epidemic of 1760 |journal=The South Carolina Historical Magazine |date=1996 |volume=97 |issue=1 |pages=30–37 |issn=0038-3082|jstor=27570134}}{{Cite web|url=https://www.usdeadlyevents.com/1760-smallpox-epidemic-charleston-sc-as-well-as-undocumented-native-deaths-730-940|title=1760 — Smallpox Epidemic, Charleston, SC (as well as undocumented Native deaths)–730-940|website=usdeadlyevents.com|date=January 1760|access-date=13 May 2020|archive-date=9 March 2021|archive-url=https://web.archive.org/web/20210309021326/https://www.usdeadlyevents.com/1760-smallpox-epidemic-charleston-sc-as-well-as-undocumented-native-deaths-730-940/|url-status=live}}

1762 Havana yellow fever epidemic

| 1762

| Havana, Cuba

| data-sort-value="8,000" | 8,000

1763 Pittsburgh area smallpox outbreak

| 1763

| North America, present-day Pittsburgh area

| data-sort-value="0"|Unknown

| {{cite journal |last1=Ranlet |first1=Philip |title=The British, the Indians, and Smallpox: What Actually Happened at Fort Pitt in 1763? |journal=Pennsylvania History: A Journal of Mid-Atlantic Studies |date=2000 |volume=67 |issue=3 |pages=427–441 |issn=0031-4528|jstor=27774278}}

1770–1772 Russian plague (part of the second plague pandemic)

| 1770–1772

| Russia

| data-sort-value="50000" | 50,000

| {{cite journal | last=Melikishvili | first=Alexander | s2cid=7420734 | year=2006 | volume=36 | pages=19–31 | journal=Critical Reviews in Microbiology | title=Genesis of the anti-plague system: the Tsarist period | issue=1 | url=http://cns.miis.edu/antiplague/pdfs/melikishvili.pdf | doi=10.1080/10408410500496763 | citeseerx=10.1.1.204.1976 | pmid=16610335 | access-date=2020-05-26 | archive-date=2009-11-23 | archive-url=https://web.archive.org/web/20091123034404/http://cns.miis.edu/antiplague/pdfs/melikishvili.pdf | url-status=live }}

1772 North America measles epidemic

| 1772

| North America

| data-sort-value="1080"|1,080

| {{cite web|url=https://www.usdeadlyevents.com/1772-measles-epidemics-charleston-sc-800-900-philadelphia-pa-180-980-1080|title=1772 — Measles Epidemics, Charleston, SC (800–900), Philadelphia, PA (180) –980-1,080|website=usdeadlyevents.com|date=January 1772|access-date=14 January 2021|archive-date=22 January 2021|archive-url=https://web.archive.org/web/20210122034326/https://www.usdeadlyevents.com/1772-measles-epidemics-charleston-sc-800-900-philadelphia-pa-180-980-1080/|url-status=live}}

1772–1773 Persian Plague (part of the second plague pandemic)

| data-sort-value="1772" | 1772–1773

| Persia

| data-sort-value="02000001" | 2 million

| {{cite journal | pmc=5037359 | pmid=27457063 | doi=10.4178/epih.e2016033 | volume=38 | title=Plague in Iran: its history and current status | year=2016 | author1=Hashemi Shahraki A | author2=Carniel E | author3=Mostafavi E | journal=Epidemiol Health | page=e2016033}}

1775–1776 England influenza outbreak

| 1775–1776

| England

1775–1782 North American smallpox epidemic

| data-sort-value="0"|Unknown

| {{Cite journal |last1=Prichard |first1=Augustin |last2=Fothergill |first2=John |year=1894 |title=Influenza in 1775 |url=https://zenodo.org/record/1663344 |journal=The Lancet |volume=143 |issue=3673 |pages=175–176 |doi=10.1016/S0140-6736(01)66026-4 |access-date=2019-07-05 |archive-url=https://web.archive.org/web/20200103214437/https://zenodo.org/record/1663344 |archive-date=2020-01-03 |url-status=live}}

| 1775–1782

| Native populations in what is now the Pacific Northwest of the United States

| 11,000+

| Greg Lange,[http://www.historylink.org/essays/output.cfm?file_id=5100 "Smallpox epidemic ravages Native Americans on the northwest coast of North America in the 1770s"] {{Webarchive|url=https://web.archive.org/web/20080526181907/http://www.historylink.org/essays/output.cfm?file_id=5100 |date=2008-05-26}}, 23 Jan 2003, HistoryLink.org, Online Encyclopedia of Washington State History, accessed 2 Jun 2008{{Cite journal |last1=Houston |first1=C. S. |last2=Houston |first2=S. |year=2000 |title=The first smallpox epidemic on the Canadian Plains: In the fur-traders' words |journal=The Canadian Journal of Infectious Diseases |volume=11 |issue=2 |pages=112–115 |doi=10.1155/2000/782978 |pmc=2094753 |pmid=18159275|doi-access=free }}

1778 Spain dengue fever outbreak

| 1778

| Spain

| data-sort-value="0"|Unknown

|{{cite book |last1=Rohé |first1=George Henry |last2=Robin |first2=Albert |title=Text-book of Hygiene: A Comprehensive Treatise on the Principles and Practice of Preventive Medicine from an American Standpoint |date=1908 |publisher=Davis |page=[https://archive.org/details/textbookhygiene00robigoog/page/n450 428] |url=https://archive.org/details/textbookhygiene00robigoog |quote=spain 1788 dengue fever. |access-date=12 February 2020 |language=en}}

1782 Influenza pandemic

|1782

|Worldwide

|Influenza

|Unknown

1788 Pueblo Indians smallpox epidemic

| 1788

| Pueblo Indians in northern New Spain (what is now the Southwestern United States)

| data-sort-value="0"|Unknown

| {{cite book |last1=Waldman |first1=Carl |last2=Braun |first2=Molly |title=Atlas of the North American Indian |date=2009 |publisher=Infobase Publishing |isbn=978-1-4381-2671-5 |page=295 |url=https://books.google.com/books?id=P2HKD9PgC6wC&q=pueblo+indian+1788+smallpox&pg=PA295 |access-date=12 February 2020 |language=en |archive-date=6 January 2024 |archive-url=https://web.archive.org/web/20240106083427/https://books.google.com/books?id=P2HKD9PgC6wC&q=pueblo+indian+1788+smallpox&pg=PA295#v=snippet&q=pueblo%20indian%201788%20smallpox&f=false |url-status=live }}

1789–1790 New South Wales smallpox epidemic

| 1789–1790

| New South Wales, Australia

1793 Philadelphia yellow fever epidemic

| data-sort-value="0"|125,251–175,351 (50–70% of native population)

| The History of Small-Pox in Australia, 1788–1908, JHL Cumpston, (1914, Government Printer, Melb.)This epidemic is unlikely to have been a natural event. see, Warren (2013) {{doi|10.1080/14443058.2013.849750}} [http://www.ahc.org.au/history/history.html After Cook and coinciding with Colonisation] "With the arrival of the Europeans, the Gadigal population was virtually wiped. In 1789 and 1790 a smallpox epidemic swept through the Aboriginal population around Sydney" {{Webarchive|url=https://web.archive.org/web/20080625020532/http://www.ahc.org.au/history/history.html |date=2008-06-25}}{{Cite web|url=https://www.thefreelibrary.com/The+origin+of+the+smallpox+outbreak+in+Sydney+in+1789.-a0180278188|title=The origin of the smallpox outbreak in Sydney in 1789.|website=thefreelibrary|access-date=14 May 2020|archive-date=8 March 2021|archive-url=https://web.archive.org/web/20210308133246/https://www.thefreelibrary.com/The+origin+of+the+smallpox+outbreak+in+Sydney+in+1789.-a0180278188|url-status=dead}}

| 1793

| Philadelphia, United States

| data-sort-value="5000"|5,000+

| {{Cite web |url=http://www.libby-genealogy.com/epidemics.htm |title=Epidemics |access-date=2008-06-08 |archive-url=https://web.archive.org/web/20130722144136/http://www.libby-genealogy.com/epidemics.htm |archive-date=2013-07-22 |url-status=live}}

1800–1803 Spain yellow fever epidemic

| 1800–1803

| Spain

| data-sort-value="60001"|60,000+

| {{Cite web |url=http://www.iberianature.com/material/tigermosquito.htm |title=Tiger mosquitoes and the history of yellow fever and dengue in Spain |access-date=16 November 2014 |archive-url=https://web.archive.org/web/20170804192609/http://www.iberianature.com/material/tigermosquito.htm |archive-date=4 August 2017 |url-status=live}}

1801 Ottoman Empire and Egypt bubonic plague epidemic

| 1801

| Ottoman Empire, Egypt

| data-sort-value="0"|Unknown

| {{Cite book |url=https://archive.org/details/b21912245 |title=Hygiene & diseases of warm climates |last=Andrew Davidson |publisher=Pentland |year=1893 |page=[https://archive.org/details/b21912245/page/337 337] |access-date=31 March 2011}}

1802–1803 Saint-Domingue yellow fever epidemic

| 1802–1803

| Saint-Domingue

| data-sort-value="42000"|29,000–55,000

| {{Cite web|url=http://s2.medicina.uady.mx/observatorio/docs/er/ac/RE2013_Ac_Marr.pdf|title=The 1802 Saint-Domingue Yellow Fever Epidemic and the Louisiana Purchase (page 78)|date=2013|access-date=12 May 2020|archive-url=https://web.archive.org/web/20160204181607/http://s2.medicina.uady.mx/observatorio/docs/er/ac/RE2013_Ac_Marr.pdf|archive-date=4 February 2016|url-status=dead}}

1812 Russia typhus epidemic

| 1812

| Russia

| 300,000

1812–1819 Ottoman plague epidemic (part of the second plague pandemic)

| 1812–1819

| Ottoman Empire

| data-sort-value="300,001"| 300,000+

| {{cite web |last1=Lynch |first1=Lily |title=Odessa, 1812: Plague and Tyranny at the Edge of the Empire |url=https://balkanist.net/plague-and-political-tyranny-odessa/ |website=Balkanist |archive-url=https://web.archive.org/web/20200213021356/https://balkanist.net/plague-and-political-tyranny-odessa/ |archive-date=13 February 2020 |date=5 December 2015}}

1813–1814 Malta plague epidemic (part of the second plague pandemic)

| 1813–1814

| Malta

| 4,500

| {{cite news |last1=Mangion |first1=Fabian |title=Maltese islands devastated by a deadly epidemic 200 years ago |url=https://timesofmalta.com/articles/view/maltese-islands-devastated-by-a-deadly-epidemic-200-years-ago.470542 |work=Times of Malta |date=19 May 2013 |access-date=28 May 2020 |archive-url=https://web.archive.org/web/20200312144053/https://timesofmalta.com/articles/view/maltese-islands-devastated-by-a-deadly-epidemic-200-years-ago.470542 |archive-date=12 March 2020}}

Caragea's plague (part of the second plague pandemic)

| 1813

| Romania

| 60,000

| Ştefan Ionescu, Bucureştii în vremea fanarioţilor (Bucharest in the time of the Phanariotes), Editura Dacia, Cluj, 1974. p. 287-293

1817–1819 Ireland typhus epidemic

| 1817–1819

| Ireland

| 65,000

| {{Cite journal |title=Typhus Epidemic in Ireland, 1817–1819: Priests, Ministers, Doctors|journal=Collectanea Hibernica|volume=41|pages=117–152|date=1999|jstor=30004680|last1=Fenning|first1=Hugh|issue=41}}

First cholera pandemic

| 1817–1824

| Asia, Europe

| data-sort-value="100,001"| 100,000+

1820 Savannah yellow fever epidemic

| 1820

| Savannah, Georgia, United States

| 700

| {{cite web|url=http://projects.leadr.msu.edu/youngamerica/exhibits/show/the-autumnal-fever|title=The Autumnal Fever: The Outbreak of the Yellow Fever in Savannah, Georgia in 1820|website=projects.leadr.msu.edu|access-date=12 May 2020|archive-date=24 February 2021|archive-url=https://web.archive.org/web/20210224231705/http://projects.leadr.msu.edu/youngamerica/exhibits/show/the-autumnal-fever|url-status=dead}}

1821 Barcelona yellow fever epidemic

| 1821

| Barcelona, Spain

| data-sort-value="12500"|5,000–20,000

| {{cite EB1911 |wstitle=Yellow Fever |volume=28 |pages=910–911}}{{cite web|url=https://iberianature.com/barcelona/tag/yellow-fever-in-spain|title=Yellow fever in Barcelona|date=14 May 2009|access-date=12 May 2020|archive-date=10 March 2021|archive-url=https://web.archive.org/web/20210310023131/https://iberianature.com/barcelona/tag/yellow-fever-in-spain/|url-status=live}}

Second cholera pandemic

| 1826–1837

| Asia, Europe, North America

| data-sort-value="100,001"| 100,000+

1828–1829 New South Wales smallpox epidemic

| 1828–1829

| New South Wales, Australia

| 19,000

| {{Cite web |url=http://www.scu.edu.au/schools/gcm/ar/arr/arow/hgkr.html |title=Aboriginal Health History |url-status=dead |archive-url=https://web.archive.org/web/20110927104026/http://www.scu.edu.au/schools/gcm/ar/arr/arow/hgkr.html |archive-date=27 September 2011 |access-date=16 November 2014 |df=dmy-all}}{{Cite web|url=https://candobetter.net/node/3720|title=The smallpox holocaust that swept Aboriginal Australia – Red hot echidna spikes are burning me|website=candobetter|access-date=14 May 2020|archive-date=3 August 2020|archive-url=https://web.archive.org/web/20200803113510/https://candobetter.net/node/3720|url-status=live}}

Groningen epidemic

| 1829

| Netherlands

| 2,800

| {{Cite web|url=https://www.rtvnoord.nl/nieuws/220326/Epidemieen-in-Groningen-De-Groninger-ziekte-1826|title=Epidemieën in Groningen: De Groninger ziekte (1826)|language=nl|website=rtvnoord|date=22 March 2020|access-date=18 April 2020|archive-date=1 April 2020|archive-url=https://web.archive.org/web/20200401142325/https://www.rtvnoord.nl/nieuws/220326/Epidemieen-in-Groningen-De-Groninger-ziekte-1826|url-status=live}}

1829–1833 Pacific Northwest malaria epidemic

| 1829–1833

| Pacific Northwest, United States

| Malaria, possibly other diseases too

| 150,000

| {{Cite web|url=https://raogk.org/encyclopedia/epidemics|title=A Listing Of Some Worldwide Epidemics|website=raogk|date=16 June 2015|access-date=18 May 2020|archive-date=14 March 2020|archive-url=https://web.archive.org/web/20200314110813/https://raogk.org/encyclopedia/epidemics/|url-status=live}}{{Cite web|url=https://oregonencyclopedia.org/articles/disease_epidemics_1770s-1850s|title=Disease Epidemics among Indians, 1770s–1850s (essay)|website=oregonencyclopedia|access-date=18 April 2020|archive-date=24 March 2020|archive-url=https://web.archive.org/web/20200324092729/https://oregonencyclopedia.org/articles/disease_epidemics_1770s-1850s/|url-status=live}}

1829–1835 Iran plague outbreak

| 1829–1835

| Iran

| data-sort-value="0"|Unknown

| [http://www.ams.ac.ir/aim/010136/0022.htm A History of the Human Plague in Iran] {{webarchive|url=https://web.archive.org/web/20110719081147/http://www.ams.ac.ir/aim/010136/0022.htm |date=2011-07-19}}, Mohammad Azizi, Farzaneh Azizi

1834–1836 Egypt plague epidemic

| 1834–1836

1837 Great Plains smallpox epidemic

| data-sort-value="0"|Unknown

| Kuhnke, Laverne. Lives at Risk: Public Health in Nineteenth-Century Egypt. [http://ark.cdlib.org/ark:/13030/ft5t1nb3mq/ ark.cdlib.org] {{Webarchive|url=https://web.archive.org/web/20081120024817/http://ark.cdlib.org/ark:/13030/ft5t1nb3mq/ |date=2008-11-20}}, Berkeley: University of California Press, c1990.

| 1837–1838

| Great Plains, United States and Canada

| data-sort-value="17,001"| 17,000+

| {{Cite web |url=https://www.nlm.nih.gov/nativevoices/timeline/293.html |title=Smallpox decimates tribes; survivors join together – Timeline – Native Voices |website=www.nlm.nih.gov |access-date=4 July 2016 |archive-url=https://web.archive.org/web/20160816170039/https://www.nlm.nih.gov/nativevoices/timeline/293.html |archive-date=16 August 2016 |url-status=live}}

1841 Southern United States yellow fever epidemic

| 1841

| Southern United States (especially Louisiana and Florida)

1847 North American typhus epidemic

| 3,498

| {{Cite web|url=https://www.usdeadlyevents.com/1841-yellow-fever-esp-fl-la-esp-new-orleans-also-vicksburg-charleston-3498|title=1841 — Yellow Fever, esp. FL & LA, esp. New Orleans, also Vicksburg, Charleston −3,498|website=usdeadlyevents.com|date=January 1840|access-date=12 May 2020|archive-date=8 March 2021|archive-url=https://web.archive.org/web/20210308205739/https://www.usdeadlyevents.com/1841-yellow-fever-esp-fl-la-esp-new-orleans-also-vicksburg-charleston-3498/|url-status=live}}

| 1847–1848

| Canada

| data-sort-value="20,001"|20,000+

|{{Cite journal |last=Gallagher |first=The Reverend John A. |year=1936 |title=The Irish Emigration of 1847 and Its Canadian Consequences |url=http://www.umanitoba.ca/colleges/st_pauls/ccha/Back%20Issues/CCHA1935-36/Gallagher.html |journal=Canadian Catholic Historical Association Report, University of Manitoba Web Site |access-date=2008-03-23 |archive-url=https://web.archive.org/web/20071011072535/http://umanitoba.ca/colleges/st_pauls/ccha/Back%20Issues/CCHA1935-36/Gallagher.html |archive-date=2007-10-11 |url-status=live}}

1847 Southern United States yellow fever epidemic

| 1847

| Southern United States (especially New Orleans)

| 3,400

| {{Cite web |url=https://www.usdeadlyevents.com/1847-yellow-fever-esp-new-orleans-also-galveston-mobile-pensacola-vicksburg-3400 |title=1847 –Yellow Fever, esp. New Orleans, also Galveston, Mobile, Pensacola, Vicksburg >3,400|website=usdeadlyevents.com|date=January 1846|access-date=12 May 2020|archive-date=9 March 2021|archive-url=https://web.archive.org/web/20210309030710/https://www.usdeadlyevents.com/1847-yellow-fever-esp-new-orleans-also-galveston-mobile-pensacola-vicksburg-3400/|url-status=live}}

1847–1848 influenza epidemic

| 1847–1848

| Worldwide

| data-sort-value="0"|Unknown

| {{cite journal |year=1849 |title=On the Influenza, or Epidemic Catarrhal Fever of 1847–8 |journal=The American Journal of the Medical Sciences |volume=18 |issue=35 |pages=148–154 |doi=10.1097/00000441-184907000-00018 |pmc=5277660|last1=a s |first1=&NA }}

1848–1849 Hawaii epidemic of infections

| 1848–1849

| Hawaiian Kingdom

| Measles, whooping cough, dysentery and influenza

| 10,000

| {{cite journal |last1=Schmitt |first1=Robert C. |last2=Nordyke |first2=Eleanor C. |title=Death in Hawai'i: the Epidemics of 1848 – 1849 |journal=Hawaiian Journal of History |date=2001 |volume=35 |hdl=10524/339 }}

1853 New Orleans yellow fever epidemic

| 1853

| New Orleans, United States

| 7,970

Third cholera pandemic

| 1846–1860

| Worldwide

| data-sort-value="01000001"|1 million+

1853 Ottoman Empire plague epidemic

| 1853

| Ottoman Empire

1853 Copenhagen cholera outbreak

| data-sort-value="0"|Unknown

| {{Cite book |url=https://books.google.com/books?id=cWUCAAAAYAAJ |title=Practitioner |year=1877 |access-date=29 March 2011}}

| 1853

| Copenhagen, Denmark

1854 Broad Street cholera outbreak

| 4,737

| {{Cite web|url=http://wayback-01.kb.dk/wayback/20100504134515/http://www2.kb.dk/udstillinger/medhist/kolera/efterhistorien.html|archiveurl=https://web.archive.org/web/20150103085703/http://wayback-01.kb.dk/wayback/20100504134515/http://www2.kb.dk/udstillinger/medhist/kolera/efterhistorien.html|url-status=dead|title=Efterhistorien|archivedate=January 3, 2015|website=wayback-01.kb.dk}}

| 1854

| London, England

| 616

| {{Cite book |url=https://archive.org/details/b28985266 |title=On the mode of communication of cholera |last=John Snow |publisher=John Churchill |year=1855 |access-date=29 March 2011}}

1855 Norfolk yellow fever epidemic

| 1855

| Norfolk and Portsmouth, England

| 3,000 (2,000 in Norfolk, 1,000 in Portsmouth)

| {{Cite web|url=https://www.historicforrest.com/norfolkHistoricalSociety/insights/2005_summer/epidemic.html|title=Norfolk's Yellow Fever Epidemic of 1855|publisher=historicforrest.com|access-date=9 May 2020|archive-date=25 June 2020|archive-url=https://web.archive.org/web/20200625155137/https://www.historicforrest.com/norfolkHistoricalSociety/insights/2005_summer/epidemic.html|url-status=live}}

Third plague pandemic

| 1855–1960

| Worldwide

| data-sort-value="12,000,010"| 12–15 million (India and China)

| {{Cite journal|last=Pryor|first=E. G.|title=The Great Plague of Hong Kong|date=1975|url=https://www.jstor.org/stable/23881624|journal=Journal of the Hong Kong Branch of the Royal Asiatic Society|volume=15|pages=61–70|jstor=23881624|pmid=11614750|issn=0085-5774|access-date=2021-05-25|archive-date=2023-02-14|archive-url=https://web.archive.org/web/20230214191621/https://www.jstor.org/stable/23881624|url-status=live}}{{cite journal |last1=Stenseth |first1=Nils Chr |title=Plague Through History |journal=Science |date=8 August 2008 |volume=321 |issue=5890 |pages=773–774 |doi=10.1126/science.1161496 |s2cid=161336516 }}

1855–1857 Montevideo yellow fever epidemic

| 1855–1857

| Montevideo, Uruguay

| 3,400 (first wave; 900, second wave; 2,500)

| {{Cite web|url=https://fiebreamarillauy.webnode.com.uy/la-fiebre-amarilla-en-el-siglo-xix/|title=La fiebre amarilla en el siglo XIX|date=13 August 2019|language=es|access-date=24 July 2021|archive-date=24 July 2021|archive-url=https://web.archive.org/web/20210724203230/https://fiebreamarillauy.webnode.com.uy/la-fiebre-amarilla-en-el-siglo-xix/|url-status=live}}

1857 Lisbon yellow fever epidemic

| 1857

| Lisbon, Portugal

| 6,000

1857 Victoria smallpox epidemic

| 1857

| Victoria, Australia

| data-sort-value="0"|Unknown

| {{Cite web |url=http://www.medicalpioneers.com/colonial.htm |title=Australian Medical Pioneers Index (AMPI) – Colonial Medical Life |access-date=16 November 2014 |archive-url=https://web.archive.org/web/20170629093854/http://medicalpioneers.com/colonial.htm |archive-date=29 June 2017 |url-status=live}}

1857–1859 Europe and the Americas influenza epidemic

| 1857–1859

| Europe, North America, South America

1862 Pacific Northwest smallpox epidemic

| data-sort-value="0"|Unknown

| Beveridge, W.I.B. Influenza, the Last Great Plague (Heinemann, London, 1977){{Page needed|date=July 2013}}

| 1862–1863

| Pacific Northwest, Canada and United States

| 20,000+

| {{Cite book|url=https://s3.amazonaws.com/hwdsbcommons/wp-content/uploads/sites/7647/2016/09/ch1_sb_topic4.pdf|title=Creating Canada: 1850–1890|access-date=14 May 2020|page=42|archive-date=3 August 2020|archive-url=https://web.archive.org/web/20200803100412/https://s3.amazonaws.com/hwdsbcommons/wp-content/uploads/sites/7647/2016/09/ch1_sb_topic4.pdf|url-status=live}}{{cite web|url=https://www.macleans.ca/news/canada/how-a-smallpox-epidemic-forged-modern-british-columbia|title=How a smallpox epidemic forged modern British Columbia|website=macleans.ca|date=August 2017|access-date=14 May 2020|archive-date=18 January 2021|archive-url=https://web.archive.org/web/20210118211838/https://www.macleans.ca/news/canada/how-a-smallpox-epidemic-forged-modern-british-columbia/|url-status=live}}{{cite book |last1= Boyd |first1= Robert |last2= Boyd |first2= Robert Thomas |title= The Coming of the Spirit of Pestilence: Introduced Infectious Diseases and Population Decline Among Northwest Coast Indians, 1774–1874 |year= 1999 |publisher= University of British Columbia Press |isbn= 978-0-295-97837-6 |chapter= A final disaster: the 1862 smallpox epidemic in coastal British Columbia |chapter-url= https://books.google.com/books?id=P_FdUPbmwCgC&pg=PA172 |pages= 172–201 |access-date= 10 February 2021 |archive-date= 6 January 2024 |archive-url= https://web.archive.org/web/20240106083406/https://books.google.com/books?id=P_FdUPbmwCgC&pg=PA172#v=onepage&q&f=false |url-status= live }}

1861–1865 United States typhoid fever epidemic

| 1861–1865

| United States

| Typhoid fever

| 80,000

| {{cite web|title=Typhoid Fever History|url=http://www.news-medical.net/health/Typhoid-Fever-History.aspx|website=news-medical.net|date=22 April 2010|access-date=13 May 2020|archive-date=13 May 2020|archive-url=https://web.archive.org/web/20200513103154/https://www.news-medical.net/health/Typhoid-Fever-History.aspx|url-status=live}}

Fourth cholera pandemic

| 1863–1875

| Middle East

| 600,000

1867 Sydney measles epidemic

| 1867

| Sydney, Australia

1871 Buenos Aires yellow fever epidemic

| 748

| {{Cite web|url=https://dictionaryofsydney.org/entry/epidemics|title=Epidemics|website=dictionaryofsydney.org|date=2008|access-date=16 May 2020|archive-date=28 March 2020|archive-url=https://web.archive.org/web/20200328053832/https://dictionaryofsydney.org/entry/epidemics|url-status=live}}

| 1871

| Buenos Aires, Argentina

| data-sort-value="19850"|13,500–26,200

| {{Cite web|url=http://www.greywall.demon.co.uk/genealogy/yfever/index.html|title=The Yellow Fever Outbreak of 1871|access-date=12 May 2020|archive-date=29 September 2019|archive-url=https://web.archive.org/web/20190929133709/http://www.greywall.demon.co.uk/genealogy/yfever/index.html|url-status=dead}}

1870–1875 Europe smallpox epidemic

| 1870–1875

| Europe

| 500,000

| {{Cite web|url=https://www.strategypage.com/articles/smallpox/6.asp|title=Franco-Prussian War|website=strategypage.com|access-date=14 May 2020|archive-date=3 August 2020|archive-url=https://web.archive.org/web/20200803125628/https://www.strategypage.com/articles/smallpox/6.asp|url-status=live}}{{cite journal|last1=Jorland|first1=Gerard|url=https://www.cairn-int.info/article-E_SEVE_033_0025--smallpox-and-the-franco-prussian-war-of.htm|title=Smallpox and the Franco-Prussian War of 1870|journal=Les Tribunes de la Santé|date=2011|volume=33|issue=4 |pages=25–30|doi=10.3917/seve.033.0025|doi-access=free|access-date=2020-05-14|archive-date=2023-04-04|archive-url=https://web.archive.org/web/20230404155043/https://www.cairn-int.info/article-E_SEVE_033_0025--smallpox-and-the-franco-prussian-war-of.htm|url-status=live}}

1875 Fiji measles outbreak

| 1875

| Fiji

1875–1876 Australia scarlet fever epidemic

| data-sort-value="40,000"| 40,000

| {{Cite news |url=http://www.britishnewspaperarchive.co.uk/viewer/bl/0000081/18750929/038/0007 |title=Death of Forty Thousand Fijians from Measles |date=29 Sep 1875 |access-date=9 Nov 2012 |publisher=Liverpool Mercury }}

| 1875–1876

| Australia

| Scarlet fever

| 8,000

1876 Ottoman Empire plague epidemic

| 1876

| Ottoman Empire

1878 New Orleans yellow fever epidemic

| 20,000

| {{Cite web|url=https://www.1902encyclopedia.com/P/PLA/plague-13.html|title=Plague in the 19th Century: (2) 1853–84|website=1902encyclopedia|access-date=16 May 2020|archive-date=3 June 2020|archive-url=https://web.archive.org/web/20200603122211/https://www.1902encyclopedia.com/P/PLA/plague-13.html|url-status=live}}

| 1878

| New Orleans, United States

1878 Mississippi Valley yellow fever epidemic

| 4,046

| 1878

| Mississippi Valley, United States

| 13,000

Fifth cholera pandemic

| 1881–1896

| Asia, Africa, Europe, South America

| data-sort-value="298,600"|298,600

1885 Montreal smallpox epidemic

| 1885

| Montreal, Canada

| 3,164

| [https://www.amazon.com/Plague-Story-Smallpox-Montreal-Michael/dp/0002156938 Plague A Story of Smallpox in Montreal] {{Webarchive|url=https://web.archive.org/web/20230404141140/https://www.amazon.com/Plague-Story-Smallpox-Montreal-Michael/dp/0002156938 |date=2023-04-04 }} Michael Bliss, 1991, accessed 8 May 2020

1889–1890 pandemic

| 1889–1890

| Worldwide

| Influenza or Human coronavirus OC43 / HCoV-OC43{{cite journal |last1=Huynh |first1=Jeremy |last2=Li |first2=Shimena |last3=Yount |first3=Boyd |last4=Smith |first4=Alexander |last5=Sturges |first5=Leslie |last6=Olsen |first6=John C. |last7=Nagel |first7=Juliet |last8=Johnson |first8=Joshua B. |last9=Agnihothram |first9=Sudhakar |last10=Gates |first10=J. Edward |last11=Frieman |first11=Matthew B. |last12=Baric |first12=Ralph S. |last13=Donaldson |first13=Eric F. |title=Evidence Supporting a Zoonotic Origin of Human Coronavirus Strain NL63 |journal=Journal of Virology |date=1 December 2012 |volume=86 |issue=23 |pages=12816–12825 |doi=10.1128/JVI.00906-12 |pmid=22993147 |pmc=3497669 }} (disputed)

| data-sort-value="01000000"|1 million

| {{Cite book |url=https://archive.org/details/b21459393 |title=Further report and papers on epidemic influenza, 1889–92: with an introduction by the medical officer of the Local Government Board |last=Great Britain. Local Government Board |publisher=Eyre |year=1893 |page=49 |access-date=29 March 2011}}

1894 Hong Kong plague (part of the third plague pandemic)

| 1894–1929

| Hong Kong

| 20,000+

| {{Cite web|date=2016-01-11|title=A lesson from history – Hong Kong's plague epidemic points way ahead in face of crisis|url=https://www.scmp.com/news/hong-kong/article/1899938/lesson-history-hong-kongs-plague-epidemic-points-way-ahead-face|access-date=2021-01-16|website=South China Morning Post|language=en|archive-date=2020-11-09|archive-url=https://web.archive.org/web/20201109000322/https://www.scmp.com/news/hong-kong/article/1899938/lesson-history-hong-kongs-plague-epidemic-points-way-ahead-face|url-status=live}}

Bombay plague epidemic (part of the third plague pandemic)

| 1896–1905

| Bombay, India

| African trypanosomiasis

| 20,788

| {{Cite web|url=https://www.outlookindia.com/website/story/opinion-colonial-experiences-from-the-bombay-plague-of-1896-no-lessons-learned/350389/?next|title=The 1896 Bombay Plague: Lessons In What Not To Do|website=outlookindia|date=9 April 2020|access-date=13 May 2020|archive-date=16 April 2020|archive-url=https://web.archive.org/web/20200416102938/https://www.outlookindia.com/website/story/opinion-colonial-experiences-from-the-bombay-plague-of-1896-no-lessons-learned/350389/?next|url-status=live}}

1896–1906 Congo Basin African trypanosomiasis epidemic

| 1896–1906

| Congo Basin

| 500,000

| {{Cite web |url=https://www.who.int/trypanosomiasis_african/country/history/en/index5.html|archive-url=https://web.archive.org/web/20080323231311/http://www.who.int/trypanosomiasis_african/country/history/en/index5.html|url-status=dead|archive-date=March 23, 2008|title=The history of sleeping sickness|website=WHO|access-date=12 May 2020}}

1899 Porto plague outbreak (part of the third plague pandemic)

| 1899

| Porto, Portugal

| 132

| {{cite thesis |last=Pontes |first=David |date=2012 |title=O cerco da peste no Porto: Cidade, imprensa e saúde pública na crise sanitária de 1899 |type=master's degree |publisher=Faculdade de Letras da Universidade do Porto |url=https://repositorio-aberto.up.pt/bitstream/10216/73326/2/28279.pdf |language=pt |access-date=2 March 2020 |archive-date=2 March 2020 |archive-url=https://web.archive.org/web/20200302232248/https://repositorio-aberto.up.pt/bitstream/10216/73326/2/28279.pdf |url-status=live }}

Sixth cholera pandemic

| 1899–1923

| Europe, Asia, Africa

| data-sort-value="800,001"| 800,000+

San Francisco plague of 1900–1904 (part of the third plague pandemic)

| 1900–1904

| San Francisco, United States

| 119

| {{Cite book |title=Plague Ports: The Global Urban Impact of Bubonic Plague: 1894–1901 |last=Echenberg |first=Myron |publisher=New York University Press |year=2007 |isbn=978-0-8147-2232-9 |location=Sacramento |page=231}}

1900 Sydney bubonic plague epidemic (part of the third plague pandemic)

| 1900

| Australia

| African trypanosomiasis

| 103

|{{Cite web|date=2015-09-03|title=The day bubonic plague hit Sydney|url=https://www.dailytelegraph.com.au/news/nsw/bubonic-plague-sydney-how-a-city-survived-the-black-death-in-1900/news-story/f36b9184eba49c72ae9791c574f7b826|access-date=2020-07-26|website=www.dailytelegraph.com.au|language=en|archive-date=2020-02-12|archive-url=https://web.archive.org/web/20200212224627/https://www.dailytelegraph.com.au/news/nsw/bubonic-plague-sydney-how-a-city-survived-the-black-death-in-1900/news-story/f36b9184eba49c72ae9791c574f7b826|url-status=live}}

1900–1920 Uganda African trypanosomiasis epidemic

| 1900–1920

| Uganda

| data-sort-value="250,000"|200,000–300,000

Papua New Guinea kuru epidemic

| 1901–2009

| Papua New Guinea

| Kuru

| 2,700–3,000+

| {{cite journal |last1=Liberski |first1=Pawel |last2=Gajos |first2=Agata |last3=Sikorska |first3=Beata |last4=Lindenbaum |first4=Shirley |title=Kuru, the First Human Prion Disease † |journal=Viruses |year=2019 |volume=11 |issue=3 |page=232 |doi=10.3390/v11030232 |pmid=30866511 |pmc=6466359 |doi-access=free }}{{cite report |last1=Zafar Khan |first1=Zartash |title=Kuru: Background, Pathophysiology, Epidemiology |date=20 July 2021 |via=emedicine.medscape.com |url=https://emedicine.medscape.com/article/220043-overview |access-date=31 July 2020 |archive-date=9 October 2023 |archive-url=https://web.archive.org/web/20231009192831/https://emedicine.medscape.com/article/220043-overview |url-status=live }}

1903 Fremantle plague epidemic (part of the third plague pandemic)

| 1903

| Fremantle, Western Australia

1906 malaria outbreak in Ceylon

| 4

| {{cite wikisource |title=Report on the outbreak of plague at Fremantle |date=1903 |first1=George Hugh Spencer |last1=Blackburne |first2=T. L. |last2=Anderson}}

| 1906–1936

| Ceylon

1918 influenza pandemic ('Spanish flu')

| 80,000

|{{Cite journal|last1=Wijesundere|first1=Dilkushi Anula|last2=Ramasamy|first2=Ranjan|date=2017-08-28|title=Analysis of Historical Trends and Recent Elimination of Malaria from Sri Lanka and Its Applicability for Malaria Control in Other Countries|journal=Frontiers in Public Health|volume=5|page=212|doi=10.3389/fpubh.2017.00212|issn=2296-2565|pmc=5581355|pmid=28894732|doi-access=free}}

Manchurian plague (part of the third plague pandemic)

| 1910–1911

| China

| Pneumonic plague

| 60,000

| {{Cite web|url=https://disasterhistory.org/the-manchurian-plague-1910-11|title=Manchurian plague, 1910–11|last=Meiklejohn|first=Iain|website=Disaster History|language=en-GB|access-date=23 April 2020|archive-date=8 March 2018|archive-url=https://web.archive.org/web/20180308205528/https://disasterhistory.org/the-manchurian-plague-1910-11|url-status=live}}

1916 United States polio epidemic

| 1916

| United States

| Poliomyelitis

| data-sort-value="7,130" | 7,130

| {{Cite journal|url=https://ourworldindata.org/polio|title=Polio (graph "Reported paralytic polio cases and deaths in the United States since 1910")|last1=Ochman|first1=Sophie|last2=Roser|first2=Max|journal=Our World in Data|date=9 November 2017|publisher=OurWorldInData.org|access-date=15 May 2020|archive-date=28 March 2018|archive-url=https://web.archive.org/web/20180328105153/https://ourworldindata.org/polio|url-status=live}}

| 1918–1920

| Worldwide

| |Influenza A virus subtype H1N1

| data-sort-value="58,500,000"| 17–100 million

| {{cite journal |last1=P. Spreeuwenberg |display-authors=etal|title=Reassessing the Global Mortality Burden of the 1918 Influenza Pandemic. |journal=American Journal of Epidemiology |volume=187|issue=12|pages=2561–2567|date=1 December 2018 |doi=10.1093/aje/kwy191 |pmid=30202996|pmc=7314216}}{{Cite journal|last=Borza|first=T.|date=2001-12-10|title=[Spanish flu in Norway 1918-19]|url=https://pubmed.ncbi.nlm.nih.gov/11808016/#affiliation-1|journal=Tidsskrift for den Norske Laegeforening|volume=121|issue=30|pages=3551–3554|issn=0029-2001|pmid=11808016|access-date=2020-12-30|archive-date=2020-08-20|archive-url=https://web.archive.org/web/20200820170537/https://pubmed.ncbi.nlm.nih.gov/11808016/#affiliation-1|url-status=live}}

1918–1922 Russia typhus epidemic

| 1918–1922

| Russia

1919–1930 encephalitis lethargica epidemic

| data-sort-value="2500000"| 2–3 million

| {{cite journal| pmc=1036775 | pmid=8246643 | doi=10.1017/s0025727300058725 | volume=37 | title=Typhus and its control in Russia, 1870–1940 | year=1993 | author=Patterson KD | journal=Med Hist |issue = 4| pages=361–381 [378]}}

| 1919–1930

| Worldwide

| Encephalitis lethargica

| data-sort-value="500,000"| 500,000

| {{Cite journal|last1=Ravenholt|first1=R. T|last2=Foege|first2=WilliamH|title=1918 Influenza, Encephalitis Lethargica, Parkinsonism|date=1982-10-16|url=http://www.sciencedirect.com/science/article/pii/S0140673682908200|journal=The Lancet|series=Originally published as Volume 2, Issue 8303|language=en|volume=320|issue=8303|pages=860–864|doi=10.1016/S0140-6736(82)90820-0|pmid=6126720|s2cid=45138249|issn=0140-6736|access-date=2020-12-23|archive-date=2021-07-12|archive-url=https://web.archive.org/web/20210712225718/https://www.sciencedirect.com/science/article/abs/pii/S0140673682908200|url-status=live}}{{Cite journal|last1=McCall|first1=Sherman|last2=Vilensky|first2=Joel A|last3=Gilman|first3=Sid|last4=Taubenberger|first4=Jeffery K|date=May 2008|title=The relationship between encephalitis lethargica and influenza: A critical analysis|journal=Journal of Neurovirology|volume=14|issue=3|pages=177–185|doi=10.1080/13550280801995445|issn=1355-0284|pmc=2778472|pmid=18569452}}{{cite book |last1=Foster |first1=Harold D. |last2=Hoffer |first2=Abram |chapter=Hyperoxidation of the Two Catecholamines, Dopamine and Adrenaline: Implications for the Etiologies and Treatment of Encephalitis Lethargica, Parkinson's Disease, Multiple Sclerosis, Amyotrophic Lateral Sclerosis, and Schizophrenia |chapter-url=https://www.sciencedirect.com/science/article/pii/B9780444528094501575 |title=Oxidative Stress and Neurodegenerative Disorders |publisher=Elsevier Science B.V. |access-date=11 February 2020 |pages=369–382 |language=en |date=1 January 2007 |doi=10.1016/B978-044452809-4/50157-5 |isbn=9780444528094 |archive-date=24 February 2020 |archive-url=https://web.archive.org/web/20200224151732/https://www.sciencedirect.com/science/article/pii/B9780444528094501575 |url-status=live }}

1924 Los Angeles pneumonic plague outbreak

| 1924

| Los Angeles, United States

| Pneumonic plague

| 30

| {{cite journal | author = Viseltear A.J. | date = March 1974 | title = The Pneumonic Plague Epidemic of 1924 in Los Angeles | journal = Yale J. Biol. Med. | volume = 47 | issue = 1| pages = 40–54| pmid = 4596466 | pmc = 2595158 }}

1924–1925 Minnesota smallpox epidemic

| 1924–1925

| Minnesota, United States

1929–1930 psittacosis pandemic

| 500

| {{Cite web |last=Nelson |first=Paul |title=Smallpox Epidemic, 1924–1925 |url=http://www.mnopedia.org/event/smallpox-epidemic-1924-1925 |work=MNopedia |date=2018-01-02 |access-date=2019-07-25 |archive-date=2014-11-04 |archive-url=https://web.archive.org/web/20141104120453/http://www.mnopedia.org/event/smallpox-epidemic-1924-1925 |url-status=live }}

1927 Montreal typhoid fever epidemic

| 1927

| Montreal, Canada

| Typhoid fever

| 538

| {{cite book|last1=Berger|first1=Stephen|title=Typhoid and Enteric Fever: Global Status: 2017 edition|url=https://books.google.com/books?id=XFEWDgAAQBAJ&q=%221993%22+%22+%09Typhoid+fever%22+%22mpumalanga%22&pg=PA11|access-date=16 May 2020|isbn=9781498816878|date=20 January 2017|publisher=GIDEON Informatics, Incorporated|archive-date=6 January 2024|archive-url=https://web.archive.org/web/20240106083908/https://books.google.com/books?id=XFEWDgAAQBAJ&q=%221993%22+%22+%09Typhoid+fever%22+%22mpumalanga%22&pg=PA11|url-status=live}}

| 1929–1930

| Worldwide

| Psittacosis

| 100+

| {{cite book|last=Honigsbaum|first=Mark|url=https://openaccess.city.ac.uk/id/eprint/23272/1/The%20Pandemic%20Century-ver3.pdf|title=The Pandemic Century: One Hundred Years of Panic, Hysteria and Hubris|publisher=Hurst & Company|year=2020|isbn=9781787381216|location=London|pages=67–98|chapter=3. The Great Parrot Fever Pandemic|access-date=2020-06-27|archive-date=2021-07-12|archive-url=https://web.archive.org/web/20210712225713/https://openaccess.city.ac.uk/id/eprint/23272/1/The%20Pandemic%20Century-ver3.pdf|url-status=live}}

1937 Croydon typhoid outbreak

| 1937

| Croydon, United Kingdom

| Typhoid fever

| 43

| {{cite journal|last1=Ravenel|first1=Mazÿk P.|date=May 1938|title=The Croydon Epidemic of Typhoid Fever|journal=American Journal of Public Health and the Nation's Health|volume=28|issue=5|pages=644–646|doi=10.2105/AJPH.28.5.644|pmid=18014847|pmc=1529192|doi-access=free|author-link1=Mazÿck P. Ravenel}}

1937 Australia polio epidemic

| 1937

| Australia

| Poliomyelitis

| Unknown

| {{Cite web |author=Professor Joan McMeeken (University of Melbourne) |date=2018-01-18 |title=Remembering Australia's polio scourge |url=https://pursuit.unimelb.edu.au/articles/remembering-australia-s-polio-scourge |access-date=2020-07-26 |website=Pursuit |language=en |archive-date=2020-07-24 |archive-url=https://web.archive.org/web/20200724050158/https://pursuit.unimelb.edu.au/articles/remembering-australia-s-polio-scourge |url-status=live }}

1940 Sudan yellow fever epidemic

| 1940

| Sudan

| 1,627

| {{Cite web|url=http://regist2.virology-education.com/presentations/2019/2ICREID/31_Magboul.pdf|title=Yellow Fever in Sudan|access-date=13 May 2020|archive-date=25 February 2021|archive-url=https://web.archive.org/web/20210225220501/http://regist2.virology-education.com/presentations/2019/2ICREID/31_Magboul.pdf|url-status=dead}}

1942–1944 Egypt malaria epidemic

| 1942–1944

| data-sort-value="0"|Unknown

| Gallagher, Nancy. Egypt's Other Wars: Epidemics and the Politics of Public Health. Syracuse University Press, c1990. American University in Cairo Press. {{ISBN|977-424-295-5}} pp. 4–6

1946 Egypt relapsing fever epidemic

| 1946

| Relapsing fever

| data-sort-value="0"|Unknown

1947 Egypt cholera epidemic

| 1947

1957–1958 influenza pandemic ('Asian flu')

| data-sort-value="10277"|10,277

| {{cite journal| pmc=2553924 | pmid=20603928 | volume=1 | title=Cholera Epidemic in Egypt (1947): A Preliminary Report | year=1948 | author=Shousha AT | journal=Bull. World Health Organ. |issue = 2| pages=353–81}}

1948–1952 United States polio epidemic

| 1948–1952

| United States

| Poliomyelitis

| data-sort-value="9000"| 9,000

| 1957–1958

| Worldwide

| Influenza A virus subtype H2N2

| data-sort-value="2,500,000"| 1–4 million

| {{Cite web|last=|first=|date=2013|title=Pandemic Influenza Risk Management WHO Interim Guidance|url=https://www.who.int/influenza/preparedness/pandemic/GIP_PandemicInfluenzaRiskManagementInterimGuidance_Jun2013.pdf?ua=1|url-status=live|archive-url=https://web.archive.org/web/20210121225326/https://www.who.int/influenza/preparedness/pandemic/GIP_PandemicInfluenzaRiskManagementInterimGuidance_Jun2013.pdf?ua=1|archive-date=2021-01-21|access-date=7 December 2020|website=World Health Organization|page=19}}{{Cite book |url=https://books.google.com/books?id=oPSG1PGmZUkC|title=Fundamental Immunology|last=William E. Paul |year=2008 |publisher=Lippincott Williams & Wilkins |isbn=978-0-7817-6519-0 |access-date=29 March 2011 |archive-url=https://web.archive.org/web/20140702155855/http://books.google.com/books?id=oPSG1PGmZUkC |archive-date=2 July 2014 |url-status=live}}

1960–1962 Ethiopia yellow fever epidemic

| 1960–1962

| Ethiopia

| Seventh cholera pandemic

| 30,000

| {{cite journal|title=Reemergence of yellow fever in Ethiopia after 50 years, 2013: epidemiological and entomological investigations|date=15 May 2017|doi=10.1186/s12879-017-2435-4|last1=Lilay|first1=Abrham|last2=Asamene|first2=Negga|last3=Bekele|first3=Abyot|last4=Mengesha|first4=Mesfin|last5=Wendabeku|first5=Milliyon|last6=Tareke|first6=Israel|last7=Girmay|first7=Abiy|last8=Wuletaw|first8=Yonas|last9=Adossa|first9=Abate|last10=Ba|first10=Yamar|last11=Sall|first11=Amadou|last12=Jima|first12=Daddi|last13=Mengesha|first13=Debritu|s2cid=21276606|journal=BMC Infectious Diseases|volume=17|issue=1|page=343|pmid=28506254|pmc=5432991|doi-access=free}}

style="font-weight: bold;"

| 1961–present

| Worldwide

| Cholera (El Tor strain)

| data-sort-value="36,000"|36,000 {{citation needed|date=February 2022}}

Hong Kong flu

| 1968–1970

| Worldwide

| Influenza A virus subtype H3N2

| data-sort-value="2,500,000"| 1–4 million

| {{cite web|url=http://apps.who.int/gb/ebwha/pdf_files/WHA64/A64_10-en.pdf|title=Report of the Review Committee on the Functioning of the International Health Regulations (2005) in relation to Pandemic (H1N1) 2009 |date=2011-05-05|page=37|url-status=live|archive-url=https://web.archive.org/web/20150514145306/http://apps.who.int/gb/ebwha/pdf_files/WHA64/A64_10-en.pdf|archive-date=14 May 2015|access-date=1 March 2015}}

1971 Staphorst polio epidemic

| 1971

| Staphorst, Netherlands

| Poliomyelitis

| 5

| {{Cite web|url=https://anderetijden.nl/aflevering/340/Polio-in-Staphorst|title=Polio in Staphorst|language=nl|website=anderetijden|access-date=15 May 2020|archive-date=20 April 2020|archive-url=https://web.archive.org/web/20200420231557/https://anderetijden.nl/aflevering/340/Polio-in-Staphorst|url-status=live}}

1972 Yugoslav smallpox outbreak

| 1972

| Yugoslavia

| Influenza A virus subtype H3N2

| 35

| {{cite journal| pmid=4826683 | volume=69 | title=[Smallpox in Yugoslavia in 1972 (author's transl)] | year=1974 | author=Ehrengut W | journal=Med Klin | issue=8 | pages=350–352}}

London flu

| 1972–1973

| United States

| 1,027

| {{Cite news |url=https://news.google.com/newspapers?id=HwohAAAAIBAJ&pg=2551,1652625 |title=New, Deadly Flu Strain Detected in Albany Co |date=January 24, 1975 |work=Schenectady Gazette |access-date=August 3, 2012 |agency=Associated Press |page=3 |archive-date=May 22, 2022 |archive-url=https://web.archive.org/web/20220522055841/https://news.google.com/newspapers?id=HwohAAAAIBAJ&pg=2551,1652625 |url-status=live }}

1973 Italy cholera epidemic

| 1973

| Italy

| Cholera (El Tor strain)

| 24

| {{cite journal | doi = 10.1016/S0140-6736(74)93214-0 | volume=303 | year=1974 | journal=The Lancet | page=669 |author1=De Lorenzo F. |author2=Manzillo G. |author3=Soscia M. |author4=Balestrieri G.G. | title=Epidemic of Cholera el Tor in Naples, 1973 | issue=7859 | pmid=4132328 }}

1974 smallpox epidemic in India

| 1974

| India

| Influenza A virus subtype H1N1

| 15,000

| {{cite web|url=http://www.smallpoxhistory.ucl.ac.uk/ |title=The control and eradication of smallpox in South Asia |website=www.smallpoxhistory.ucl.ac.uk |access-date=2008-12-18 |url-status=dead |archive-url=https://web.archive.org/web/20081019023043/http://www.smallpoxhistory.ucl.ac.uk/ |archive-date=2008-10-19}}

1977 Russian flu

| 1977–1979

| Worldwide

| 700,000

| {{Cite journal|last1=Michaelis|first1=Martin|last2=Doerr|first2=Hans Wilhem|last3=Cinatl|first3=Jindrich|date=2009-08-01|title=Novel swine-origin influenza A virus in humans: another pandemic knocking at the door|journal=Medical Microbiology and Immunology|language=en|volume=198|issue=3|pages=175–183 (Table 1)|doi=10.1007/s00430-009-0118-5|pmid=19543913|s2cid=20496301|issn=1432-1831|doi-access=free}}{{Cite web|last=|first=|date=2020-11-18|title=You're more likely to die from the H1N1 flu if you were born in 1957|url=https://nouvelles.umontreal.ca/en/article/2018/01/19/you-re-more-likely-to-die-from-the-h1n1-flu-if-you-were-born-in-1957/|access-date=2021-01-24|website=University of Montreal|language=en|archive-date=2019-01-31|archive-url=https://web.archive.org/web/20190131183201/https://nouvelles.umontreal.ca/en/article/2018/01/19/you-re-more-likely-to-die-from-the-h1n1-flu-if-you-were-born-in-1957/|url-status=dead}}

Sverdlovsk anthrax leak

| 1979

| Russia

| Anthrax

| 105

| {{Cite journal|last1=Meselson|first1=Matthew|last2=Guillemin|first2=J|last3=Hugh-Jones|first3=Martin|last4=Langmuir|first4=A|last5=Popova|first5=I|last6=Shelokov|first6=A|last7=Yampolskaya|first7=O|date=1994-12-01|title=The Sverdlovsk anthrax outbreak of 1979|url=https://www.researchgate.net/publication/15224942|journal=Science|volume=266|issue=5188|pages=1202–8|doi=10.1126/science.7973702|pmid=7973702|bibcode=1994Sci...266.1202M|access-date=2020-07-31|archive-date=2021-07-12|archive-url=https://web.archive.org/web/20210712225710/https://www.researchgate.net/publication/15224942_The_Sverdlovsk_anthrax_outbreak_of_1979|url-status=live}}

| {{strong|1981–present}}

| {{strong|Worldwide}}

| {{strong|HIV/AIDS}}

| data-sort-value="44000000" | {{strong|44 million ({{as of|2025|lc=y}})}}

| {{Cite web|title=Global HIV and AIDS statistics|url=https://www.unaids.org/en/resources/fact-sheet|access-date=2021-08-23|website=UNAIDS|archive-date=2019-12-04|archive-url=https://web.archive.org/web/20191204021652/https://www.unaids.org/en/resources/fact-sheet|url-status=live}}

1984 Western Sahara plague

| 1984

| Western Sahara

| 64

| {{Citation needed|date=May 2020}}

1986 Oju yellow fever epidemic

| 1986

| Oju, Nigeria

| 5,600+

| {{Cite journal |title=Epidemic yellow fever in eastern Nigeria, 1986.| pmid=2894558 | doi=10.1016/s0140-6736(88)91425-0 | volume=1 | year=1988 | author1=De Cock KM |author2=Monath TP |author3=Nasidi A |author4=Tukei PM |author5=Enriquez J |author6=Lichfield P |author7=Craven RB |author8=Fabiyi A |author9=Okafor BC |author10=Ravaonjanahary C | journal=Lancet | issue=8586 | pages=630–3| s2cid=31563771 }}

1987 Mali yellow fever epidemic

| 1987

| Mali

| 145

| {{Cite web |url=https://www.who.int/csr/don/2005_01_06/en|archive-url=https://web.archive.org/web/20050109054957/http://www.who.int/csr/don/2005_01_06/en/|url-status=dead|archive-date=January 9, 2005|title=Yellow fever in Mali|website=who.int|access-date=12 May 2020}}

1988 Shanghai hepatitis A epidemic

| 1988

| Shanghai, China

| Hepatitis A

| 31–47

|{{Cite journal|last=Cooksley|first=W. G.|date=May 2000|title=What did we learn from the Shanghai hepatitis A epidemic?|url=https://pubmed.ncbi.nlm.nih.gov/10870174/|journal=Journal of Viral Hepatitis|volume=7|issue=Suppl 1|pages=1–3|doi=10.1046/j.1365-2893.2000.00021.x|issn=1352-0504|pmid=10870174|s2cid=34673718|access-date=2021-08-04|archive-date=2021-08-04|archive-url=https://web.archive.org/web/20210804051210/https://pubmed.ncbi.nlm.nih.gov/10870174/|url-status=live}}{{Cite web|date=2013-07-23|title=City getting tougher on blood clam ban|url=https://archive.shine.cn/Metro/health-and-science/City-getting-tougher-on-blood-clam-ban/shdaily.shtml|access-date=2021-08-04|website=Shanghai Daily|archive-date=2019-07-19|archive-url=https://web.archive.org/web/20190719162729/https://archive.shine.cn/Metro/health-and-science/City-getting-tougher-on-blood-clam-ban/shdaily.shtml|url-status=live}}{{Cite journal|last1=Halliday|first1=Mabel L.|last2=Kang|first2=Lai-Yi|last3=Zhou|first3=Ting-Kui|last4=Hu|first4=Meng-Dong|last5=Pan|first5=Qi-Chao|last6=Fu|first6=Ting-Yuan|last7=Huang|first7=Yu-Sheng|last8=Hu|first8=Shan-Lian|date=1991|title=An Epidemic of Hepatitis A Attributable to the Ingestion of Raw Clams in Shanghai, China|url=https://www.jstor.org/stable/30111993|journal=The Journal of Infectious Diseases|volume=164|issue=5|pages=852–859|doi=10.1093/infdis/164.5.852|jstor=30111993|pmid=1658157|issn=0022-1899|access-date=2021-08-04|archive-date=2023-07-02|archive-url=https://web.archive.org/web/20230702210425/https://www.jstor.org/stable/30111993|url-status=live}}

1991 Bangladesh cholera epidemic

| 1991

| Bangladesh

| data-sort-value="8921"|8,410–9,432

| [https://web.archive.org/web/20130609154502/http://www.who.int/bulletin/volumes/90/3/BLT-11-093427-table-T3.html Summary of cholera cases and deaths reported in the literature, by date, country and World Health Organization (WHO) mortality stratum] Mohammad Ali, Anna Lena Lopez, Young Ae You, Young Eun Kim, Binod Sah, Brian Maskery & John Clemens, Bulletin of the World Health Organization, Volume 90, Number 3, March 2012, 209-218A www.who.int, accessed 4 May 2020

1991 Latin America cholera epidemic

| 1991–1993

| Peru, Chile, Bolivia, Ecuador, Colombia, Mexico, El Salvador, Guatemala

United Kingdom BSE outbreak

| 8,000

|{{Cite journal|last1=Tickner|first1=Joel|last2=Gouveia-Vigeant|first2=Tami|date=June 2005|title=The 1991 Cholera Epidemic in Peru: Not a Case of Precaution Gone Awry|journal=Risk Analysis|language=en|volume=25|issue=3|pages=495–502|doi=10.1111/j.1539-6924.2005.00617.x|pmid=16022685|bibcode=2005RiskA..25..495T |s2cid=15792284}}{{Cite journal|date=1991|title=Cholera in the Americas|journal=Bulletin of the Pan American Health Organization|volume=25|issue=3|pages=267–273|issn=0085-4638|pmid=1742573}}

1994 plague in India

| 1994

| India

| Bubonic plague and Pneumonic plague

| 56

| {{Cite journal |last=Dutt |first=Ashok |date=2006 |title=Surat Plaque of 1994 re-examined |url=http://www.tm.mahidol.ac.th/seameo/2006_37_4/21-3658.pdf |journal=Southeast Asian Journal of Tropical Medicine and Public Health |volume=37 |issue=4 |pages=755–760 |access-date=19 June 2016 |archive-url=https://web.archive.org/web/20160206192456/http://www.tm.mahidol.ac.th/seameo/2006_37_4/21-3658.pdf |archive-date=6 February 2016 |url-status=live |pmid=17121302}}

| 1996–2001

| United Kingdom

| Variant Creutzfeldt–Jakob disease / vCJD

| 178

| {{Cite web|url=https://www.bbc.com/news/uk-45906585|title='Mad cow disease': What is BSE?|website=BBC|date=18 October 2018|access-date=12 May 2020|archive-date=3 May 2020|archive-url=https://web.archive.org/web/20200503234655/https://www.bbc.com/news/uk-45906585|url-status=live}}{{cite web |title=Variant Creutzfeldt–Jakob Disease, Current Data (July 2012) |url=http://www.cjd.ed.ac.uk/vcjdworld.htm |access-date=20 April 2020 |publisher=The National Creutzfeldt–Jakob Disease Surveillance Unit (NCJDSU), University of Edinburgh |url-status=bot: unknown |archive-url=https://web.archive.org/web/20120721234746/http://www.cjd.ed.ac.uk/vcjdworld.htm |archive-date=21 July 2012 |df=dmy}};

1996 West Africa meningitis epidemic

| 1996

| West Africa

| Meningitis

| data-sort-value="10000"|10,000

| [https://www.nytimes.com/1996/05/08/world/wide-epidemic-of-meningitis-fatal-to-10000-in-west-africa.html Wide Epidemic of Meningitis Fatal to 10,000 in West Africa] {{Webarchive|url=https://web.archive.org/web/20230711163624/https://www.nytimes.com/1996/05/08/world/wide-epidemic-of-meningitis-fatal-to-10000-in-west-africa.html |date=2023-07-11 }} Eoward W. French, 8 May 1996 www.nytimes.com, accessed 26 April 2020

1998–1999 Malaysia Nipah virus outbreak

| 1998–1999

| Malaysia

| Nipah virus infection

| 105

| {{cite journal|url=http://www.mjpath.org.my/2007.2/02Nipah_Virus_lessons.pdf|title=Lessons from the Nipah virus outbreak in Malaysia|author1=Lai-Meng Looi|author2=Kaw-Bing Chua|publisher=Department of Pathology, University of Malaya and National Public Health Laboratory of the Ministry of Health, Malaysia|journal=The Malaysian Journal of Pathology|year=2007|volume=29|number=2|pages=63–7|pmid=19108397|archive-url=https://web.archive.org/web/20190830060915/http://www.mjpath.org.my/2007.2/02Nipah_Virus_lessons.pdf|archive-date=30 August 2019|url-status=live}}

1998–2000 Democratic Republic of the Congo Marburg virus outbreak

| 1998–2000

| Marburg virus

| 128

| {{Cite web|url=https://www.cdc.gov/vhf/marburg/resources/outbreak-table.html|title=Outbreak Table | Marburg Hemorrhagic Fever | CDC|access-date=2021-08-13|archive-date=2015-01-21|archive-url=https://web.archive.org/web/20150121181229/http://www.cdc.gov/vhf/marburg/resources/outbreak-table.html|url-status=live}}

2000 Central America dengue epidemic

| 2000

| Central America

| data-sort-value="40"| 40+

| {{Cite web |url=http://www.paho.org/English/sha/be_v21n4-dengue.htm |title=Dengue in the Americas: The Epidemics of 2000 |access-date=2008-08-05 |archive-url=https://web.archive.org/web/20171017153210/http://www1.paho.org/English/sha/be_v21n4-dengue.htm |archive-date=2017-10-17 |url-status=live}}

2001 Nigeria cholera epidemic

| 2001

| Nigeria

| data-sort-value="401"| 400+

| {{Cite news |url=http://news.bbc.co.uk/1/hi/world/africa/1677526.stm |title=Nigeria cholera outbreak kills 400 |date=2001-11-26 |access-date=16 November 2014 |archive-url=https://web.archive.org/web/20031219043217/http://news.bbc.co.uk/1/hi/world/africa/1677526.stm |archive-date=19 December 2003 |url-status=live}}

2001 South Africa cholera epidemic

| 2001

| South Africa

| Severe acute respiratory syndrome / SARS

| 139

| {{Cite web |url=http://www.redcross.org/news/in/health/010312cholera.html |title=Cholera Spreads Through South Africa Townships |access-date=16 November 2014 |archive-url=https://web.archive.org/web/20090603003241/http://www.redcross.org/news/in/health/010312cholera.html |archive-date=3 June 2009 |url-status=dead}}[https://web.archive.org/web/20040710091424/http://www.who.int/csr/don/2001_03_16/en/ 2001 – Cholera in South Africa] 16 March 2001 www.who.int, accessed 28 April 2020

2002–2004 SARS outbreak

| 2002–2004

| Worldwide

| 774

| {{Cite web | url=https://www.who.int/csr/sars/country/table2004_04_21/en/ | title=WHO | Summary of probable SARS cases with onset of illness from 1 November 2002 to 31 July 2003 | access-date=5 April 2020 | archive-date=19 March 2020 | archive-url=https://web.archive.org/web/20200319162659/https://www.who.int/csr/sars/country/table2004_04_21/en/ | url-status=live }}

2003–2019 Asia and Egypt avian influenza epidemic

| 2003–2019

| China, Southeast Asia and Egypt

| Influenza A virus subtype H5N1

| 455

| {{Cite web|url=https://www.who.int/influenza/human_animal_interface/2020_MAY_tableH5N1.pdf|title=Cumulative number of confirmed human cases for avian influenza A(H5N1) reported to WHO, 2003 – 2020|date=8 May 2020|access-date=4 January 2020|archive-date=3 June 2020|archive-url=https://web.archive.org/web/20200603072330/https://www.who.int/influenza/human_animal_interface/2020_MAY_tableH5N1.pdf|url-status=live}}

2004 Indonesia dengue epidemic

| 2004

| Indonesia

| 658

| [https://web.archive.org/web/20040530112333/http://www.who.int/csr/don/2004_05_11a/en/ Dengue fever in Indonesia – update 4] 11 May 2004 www.who.int, accessed 16 February 2020

2004 Sudan Ebola outbreak

| 2004

| Sudan

2005 dengue outbreak in Singapore

| 7

2004–2005 Angola Marburg virus outbreak

| 2004–2005

| Angola

| Marburg virus

| 227

| 2005

| Singapore

| 27

| {{Cite journal |last1=Koh |first1=B. K. |last2=Ng |first2=L. C. |last3=Kita |first3=Y. |last4=Tang |first4=C. S. |last5=Ang |first5=L. W. |last6=Wong |first6=K. Y. |last7=James |first7=L. |last8=Goh |first8=K. T. |year=2008 |title=The 2005 dengue epidemic in Singapore: Epidemiology, prevention and control |url=http://www.annals.edu.sg/pdf/37VolNo7Jul2008/V37N7p538.pdf |journal=Annals of the Academy of Medicine, Singapore |volume=37 |issue=7 |pages=538–545 |doi=10.47102/annals-acadmedsg.V37N7p538 |pmid=18695764 |s2cid=31640849 |access-date=2018-10-17 |archive-url=https://web.archive.org/web/20170706065103/http://www.annals.edu.sg/PDF/37VolNo7Jul2008/V37N7p538.pdf |archive-date=2017-07-06 |url-status=live}}

2006 Luanda cholera epidemic

| 2006

| Luanda, Angola

| Ituri Province, Democratic Republic of the Congo

| data-sort-value="1200"| 1,200+

| [http://news.bbc.co.uk/2/hi/africa/4990960.stm Worst cholera outbreak in Angola] {{Webarchive|url=https://web.archive.org/web/20170429080644/http://news.bbc.co.uk/2/hi/africa/4990960.stm |date=2017-04-29}}, BBC

2006 Ituri Province plague epidemic

| 2006

| 61

| [https://web.archive.org/web/20141015101105/http://www.who.int/csr/don/2006_06_14/en/ Plague in the Democratic Republic of the Congo] 14 June 2006 www.who.int, accessed 26 February 2020[https://web.archive.org/web/20140227135856/http://www.who.int/csr/don/2006_10_13/en/ Plague in the Democratic Republic of the Congo] 13 October 2006 www.who.int, accessed 26 February 2020

2006 India malaria outbreak

| 2006

| India

2006 dengue outbreak in India

| 17

| {{Cite web |url=http://www.bio-medicine.org/medicine-news/Malaria-Epidemic-Sweeps-Northeast-India-9507-1/ |title=Malaria Epidemic Sweeps Northeast India |access-date=2008-07-01 |archive-url=https://web.archive.org/web/20170203074542/http://www.bio-medicine.org/medicine-news/Malaria-Epidemic-Sweeps-Northeast-India-9507-1/ |archive-date=2017-02-03 |url-status=live}}

| 2006

| India

2006 dengue outbreak in Pakistan

| data-sort-value="50"| 50+

| {{Cite web |url=http://www.news-medical.net/?id=20348 |title=Dengue epidemic threatens India's capital |date=2 October 2006 |website=News-Medical.net |access-date=16 November 2014 |archive-url=https://web.archive.org/web/20090115204240/http://www.news-medical.net/?id=20348 |archive-date=15 January 2009 |url-status=live}}

| 2006

| Pakistan

| data-sort-value="50"| 50+

| {{Cite journal |last1=Khan |first1=E. |last2=Siddiqui |first2=J. |last3=Shakoor |first3=S. |last4=Mehraj |first4=V. |last5=Jamil |first5=B. |last6=Hasan |first6=R. |year=2007 |title=Dengue outbreak in Karachi, Pakistan, 2006: Experience at a tertiary care center |journal=Transactions of the Royal Society of Tropical Medicine and Hygiene |volume=101 |issue=11 |pages=1114–1119 |doi=10.1016/j.trstmh.2007.06.016 |pmid=17706259}}

2006 Philippines dengue epidemic

| 2006

| Philippines

2006–2007 East Africa Rift Valley fever outbreak

| data-sort-value="1000"|1,000

| [https://www.researchgate.net/publication/267872402_Epidemiology_of_Dengue_Disease_in_the_Philippines_2000-2011_A_Systematic_Literature_Review Epidemiology of Dengue Disease in the Philippines (2000–2011): A Systematic Literature Review] {{Webarchive|url=https://web.archive.org/web/20230711163235/https://www.researchgate.net/publication/267872402_Epidemiology_of_Dengue_Disease_in_the_Philippines_2000-2011_A_Systematic_Literature_Review |date=2023-07-11 }} November 2014 PLoS Neglected Tropical Diseases via www.researchgate.net, accessed 16 February 2020

| 2006–2007

| East Africa

| Rift Valley fever

| 394

| [https://www.who.int/news-room/fact-sheets/detail/rift-valley-fever Rift Valley fever] {{Webarchive|url=https://web.archive.org/web/20211009062914/https://www.who.int/news-room/fact-sheets/detail/rift-valley-fever |date=2021-10-09 }} 19 February 2018 www.who.int, accessed 26 April 2020

Mweka Ebola epidemic

| 2007

| 187

| [http://www.smh.com.au/news/world/mourners-die-as-fever-grips-congo/2007/08/30/1188067243698.html "Mourners die as fever grips Congo."] {{Webarchive|url=https://web.archive.org/web/20121023063718/http://www.smh.com.au/news/world/mourners-die-as-fever-grips-congo/2007/08/30/1188067243698.html |date=2012-10-23}} Sydney Morning Herald, August 30, 2007

2007 Ethiopia cholera epidemic

| 2007

| Ethiopia

2007 Iraq cholera outbreak

| 684

| {{Cite news |url=https://www.theguardian.com/world/2007/feb/22/ethiopia |title=Fatal outbreak not a cholera epidemic, insists Ethiopia |last=Xan Rice |date=2007-02-22 |work=The Guardian |access-date=16 November 2014 |archive-url=https://web.archive.org/web/20171026111149/https://www.theguardian.com/world/2007/feb/22/ethiopia |archive-date=26 October 2017 |url-status=live}}

| 2007

| Iraq

| 10

| [http://www.nbcnews.com/id/21121516 Cholera outbreak in Iraq growing] {{Webarchive|url=https://web.archive.org/web/20170204003658/http://www.nbcnews.com/id/21121516/ |date=2017-02-04}}, Associated Press

2007 Puerto Rico, Dominican Republic, and Mexico dengue fever epidemic

| 2007

| Puerto Rico, Dominican Republic, Mexico

| 183

| [http://www.alertnet.org/thenews/newsdesk/NA5209573.htm Dengue fever epidemic hits Caribbean, Latin America] {{Webarchive|url=https://web.archive.org/web/20090803084737/http://www.alertnet.org/thenews/newsdesk/NA5209573.htm |date=2009-08-03}}, Reuters

2007 Uganda Ebola outbreak

| 2007

| Uganda

| 37

| {{cite press release | title = Ebola virus disease | url = https://www.who.int/en/news-room/fact-sheets/detail/ebola-virus-disease | publisher = World Health Organization (WHO) | access-date = 26 February 2020 | date = 12 February 2018 | df = dmy-all | archive-date = 18 April 2018 | archive-url = https://web.archive.org/web/20180418095601/http://www.who.int/mediacentre/factsheets/fs103/en/ | url-status = live }}

2007 Netherlands Q-fever epidemic

| 2007–2018

| Netherlands

| Q-fever

| 95

| {{Cite web|url=https://www.nu.nl/binnenland/5550881/q-koorts-nog-niet-voorbij-in-totaal-al-95-doden.html|title=Q-koorts nog niet voorbij: In totaal al 95 doden|language=Dutch|website=nu.nl|date=3 November 2018|access-date=4 February 2021|archive-date=9 February 2021|archive-url=https://web.archive.org/web/20210209141633/https://www.nu.nl/binnenland/5550881/q-koorts-nog-niet-voorbij-in-totaal-al-95-doden.html|url-status=live}}

2008 Brazil dengue epidemic

| 2008

| Brazil

| 67

| [https://edition.cnn.com/2008/HEALTH/conditions/04/03/brazil.dengue/index.html Thousands hit by Brazil outbreak of dengue] {{Webarchive|url=https://web.archive.org/web/20230711162221/https://edition.cnn.com/2008/HEALTH/conditions/04/03/brazil.dengue/index.html |date=2023-07-11 }} edition.cnn.com, accessed 16 February 2020

2008 Cambodia dengue epidemic

| 2008

| Cambodia

| 407

| [http://www.alertnet.org/thenews/newsdesk/BKK133167.htm Cambodia suffers worst dengue epidemic, 407 dead] {{Webarchive|url=https://web.archive.org/web/20091111203520/http://www.alertnet.org/thenews/newsdesk/BKK133167.htm |date=2009-11-11}}, Reuters

2008 Chad cholera epidemic

| 2008

| Chad

| Hand, foot, and mouth disease

| 123

| {{Cite web |url=http://www.irinnews.org/report.aspx?reportid=51238 |title=Cholera epidemic in western Chad kills 123 |access-date=2008-06-08 |archive-url=https://web.archive.org/web/20090112054136/http://www.irinnews.org/report.aspx?reportid=51238 |archive-date=2009-01-12 |url-status=live |date=2004-09-02}}

2008–2017 China hand, foot, and mouth disease epidemic

| 2008–2017

| China

| data-sort-value="3322" | 3,322+

| {{cite journal |doi=10.3201/eid2403.171303|title=Epidemiology of Recurrent Hand, Foot and Mouth Disease, China, 2008–2015|year=2018|last1=Huang|first1=Jiao|last2=Liao|first2=Qiaohong|last3=Ooi|first3=Mong How|last4=Cowling|first4=Benjamin J.|last5=Chang|first5=Zhaorui|last6=Wu|first6=Peng|last7=Liu|first7=Fengfeng|last8=Li|first8=Yu|last9=Luo|first9=Li|last10=Yu|first10=Shuanbao|last11=Yu|first11=Hongjie|last12=Wei|first12=Sheng|journal=Emerging Infectious Diseases|volume=24|issue=3|pages=432–442 |pmid=29460747|pmc=5823341}}2008–2015, ≈13 million HFMD cases were reported, including 123,261 severe cases and 3,322 deaths in 31 provinces of mainland China

2008 India cholera epidemic

| 2008

| India

| 115

| [http://news.bbc.co.uk/2/hi/south_asia/6968281.stm Cholera death toll in India rises] {{Webarchive|url=https://web.archive.org/web/20171111043033/http://news.bbc.co.uk/2/hi/south_asia/6968281.stm |date=2017-11-11}}, BBC News

2008 Madagascar plague outbreak

| 2008

| Madagascar

| data-sort-value="18"| 18+

| {{Cite web|url=http://eldib.wordpress.com/2008/01/10/2175/|archive-url=https://web.archive.org/web/20090509210150/http://eldib.wordpress.com/2008/01/10/2175/|url-status=dead|title=Madagascar: eighteen dead from Bubonic Plague, five in hospital since 1 January 2008|archive-date=May 9, 2009}}

2008 Philippines dengue epidemic

| 2008

| Philippines

2008 Zimbabwean cholera outbreak

| data-sort-value="172" |172

| {{Cite web |url=http://www.terradaily.com/reports/Dengue_cases_in_Philippines_rise_by_43_percent_government_999.html |title=Dengue cases in Philippines rise by 43 percent: government |access-date=16 November 2014 |archive-url=https://web.archive.org/web/20171017153157/http://www.terradaily.com/reports/Dengue_cases_in_Philippines_rise_by_43_percent_government_999.html |archive-date=17 October 2017 |url-status=live}}

| 2008–2009

| Zimbabwe

2009 Bolivian dengue fever epidemic

| data-sort-value="4293"|4,293

| {{cite web |url=https://www.who.int/cholera/countries/ZimbabweCountryProfileOct2009.pdf |access-date=16 February 2020 |title=Cholera Country Profile: Zimbabwe |date=31 October 2009 |publisher=World Health Organization – Global Task Force on Cholera Control |archive-date=31 October 2017 |archive-url=https://web.archive.org/web/20171031123847/http://www.who.int/cholera/countries/ZimbabweCountryProfileOct2009.pdf |url-status=live }}

| 2009

| Bolivia

2009 Gujarat hepatitis outbreak

| 18

| {{cite journal| pmc=3516305 | pmid=23042846 | doi=10.4269/ajtmh.2012.11-0770 | volume=87 | title=The history of dengue outbreaks in the Americas | year=2012 | author1=Brathwaite Dick O |author2=San Martín JL |author3=Montoya RH |author4=del Diego J |author5=Zambrano B |author6=Dayan GH | journal=Am J Trop Med Hyg | issue=4 | pages=584–593}}

| 2009

| India

| Hepatitis B

| 49

| {{Cite web |url=http://www.ndtv.com/convergence/ndtv/story.aspx?id=NEWEN20090084387 |title=NDTV Report |access-date=2009-02-23 |archive-url=https://web.archive.org/web/20090225134231/http://www.ndtv.com/convergence/ndtv/story.aspx?id=NEWEN20090084387 |archive-date=2009-02-25 |url-status=dead}}

Queensland 2009 dengue outbreak

| 2009

| Queensland, Australia

2009–2010 West African meningitis outbreak

| data-sort-value="1.1"| 1+ (503 cases)

| {{Cite journal |last=McCredie |first=J. |s2cid=41469446 |year=2009 |title=Dengue fever epidemic hits northern Australia |journal=BMJ |volume=338 |issue=mar09 2 |pages=b967 |doi=10.1136/bmj.b967 |pmid=19273518}}

| 2009–2010

| West Africa

| Meningitis

| data-sort-value="1100"|1,100

| {{Cite journal |last=Odigwe |first=C. |s2cid=11085562 |year=2009 |title=West Africa has worst meningitis epidemic for 10 years |journal=BMJ |volume=338 |issue=apr21 1 |pages=b1638 |doi=10.1136/bmj.b1638 |pmid=19383759}}

rowspan="2" | 2009 swine flu pandemic

| rowspan="2" | 2009–2010

| rowspan="2" | Worldwide

| rowspan="2" | Influenza A virus subtype H1N1

| data-sort-value="284,000"|Lab confirmed deaths: 18,449 (reported to the WHO)

|{{Cite web|url=https://www.cdc.gov/flu/spotlights/pandemic-global-estimates.htm|title=First Global Estimates of 2009 H1N1 Pandemic Mortality Released by CDC-Led Collaboration|date=2019-11-20|website=www.cdc.gov|language=en-us|access-date=2020-03-12|archive-date=2020-03-03|archive-url=https://web.archive.org/web/20200303012120/https://www.cdc.gov/flu/spotlights/pandemic-global-estimates.htm|url-status=live}}

Estimated death toll: 284,000 (possible range 151,700–575,400)

|{{Cite web |title=Pandemic (H1N1) 2009 – update 112 |url=https://www.who.int/csr/don/2010_08_06/en/ |url-status=dead |archive-url=https://web.archive.org/web/20110327194118/http://www.who.int/csr/don/2010_08_06/en/ |archive-date=March 27, 2011 |access-date=October 3, 2020}}()

2010s Haiti cholera outbreak

| 2010–2019

| Haiti

| Cholera (strain serogroup O1, serotype Ogawa)

| data-sort-value="10075"|10,075

| {{cite web |title=Epidemiological Update Cholera 28 Dec 2017 |website=www.paho.org |url=http://www.paho.org/hq/index.php?option=com_docman&task=doc_download&Itemid=&gid=43291&lang=pt |access-date=15 May 2020 |archive-date=12 July 2021 |archive-url=https://web.archive.org/web/20210712225758/https://www.paho.org/hq/dmdocuments/2017/2017-dec-28-phe-epi-update-cholera.pdf |url-status=live }}

2010–2014 Democratic Republic of the Congo measles outbreak

| 2010–2014

| Hand, foot, and mouth disease

| data-sort-value="4,501"| 4,500+

| {{Cite web |url=http://www.doctorswithoutborders.org/press/release.cfm?id=5132&cat=press-release |title=Doctorswithoutborders.org |website=MSF USA |url-status=dead |archive-url=https://web.archive.org/web/20110927220605/http://www.doctorswithoutborders.org/press/release.cfm?id=5132&cat=press-release |archive-date=27 September 2011 |access-date=16 November 2014}}{{Cite web |url=http://www.msf.org/article/democratic-republic-congo-more-measles-vaccinations-needed |title=Democratic Republic of Congo: More measles vaccinations needed |website=Médecins Sans Frontières (MSF) International |access-date=16 November 2014 |archive-url=https://web.archive.org/web/20141102114052/http://www.msf.org/article/democratic-republic-congo-more-measles-vaccinations-needed |archive-date=2 November 2014 |url-status=live}}

2011 Vietnam hand, foot, and mouth disease epidemic

| 2011

| Vietnam

| 170

| [https://news.yahoo.com/vietnam-alert-common-virus-kills-81-children-071532226.html Vietnam on alert as common virus kills 81 children – Yahoo News] {{Webarchive|url=https://web.archive.org/web/20160305003723/http://news.yahoo.com/vietnam-alert-common-virus-kills-81-children-071532226.html |date=2016-03-05}}. News.yahoo.com (2011-08-19). Retrieved on 2014-05-12.{{Cite journal |last1=Nguyen |first1=Ngoc TB |last2=Pham |first2=Hau V. |last3=Hoang |first3=Cuong Q. |last4=Nguyen |first4=Tien M. |last5=Nguyen |first5=Long T. |last6=Phan |first6=Hung C. |last7=Phan |first7=Lan T. |last8=Vu |first8=Long N. |last9=Tran Minh |first9=Nguyen N. |year=2014 |title=Epidemiological and clinical characteristics of children who died from hand, foot and mouth disease in Vietnam, 2011 |journal=BMC Infectious Diseases |volume=14 |issue=1 |pages=341 |doi=10.1186/1471-2334-14-341 |pmc=4068316 |pmid=24942066 |doi-access=free }}

2011 dengue outbreak in Pakistan

| 2011

| Pakistan

2012 yellow fever outbreak in Darfur, Sudan

| data-sort-value="350"| 350+

| [http://www.emro.who.int/surveillance-forecasting-response/surveillance-events/conference-on-dengue-control.html Surveillance, forecasting and response International conference on dengue control, 27–29 February 2012] {{Webarchive|url=https://web.archive.org/web/20230711162017/http://www.emro.who.int/surveillance-forecasting-response/surveillance-events/conference-on-dengue-control.html |date=11 July 2023 }} www.emro.who.int accessed 16 February 2020

| 2012

| Darfur, Sudan

|Middle East respiratory syndrome / MERS-CoV

| 171

| {{Cite journal |last1=Yuill |first1=Thomas M. |last2=Woodall |first2=John P. |last3=Baekeland |first3=Susan |year=2013 |title=Latest outbreak news from ProMED-mail. Yellow fever outbreak–Darfur Sudan and Chad |journal=International Journal of Infectious Diseases |volume=17 |issue=7 |pages=e476–e478 |doi=10.1016/j.ijid.2013.03.009|doi-access=free }}

style="font-weight: bold;"

| MERS outbreak

| 2012–present

| Worldwide

| data-sort-value="941"|941 ({{as of|2021|May|8|lc=y}})

| {{Cite web|date=1 February 2021|title=Geographical distribution of confirmed MERS-CoV cases by country of infection and year|url=https://www.ecdc.europa.eu/en/publications-data/geographical-distribution-confirmed-mers-cov-cases-country-infection-and-year|access-date=28 February 2021|website=European Centre for Disease Prevention and Control|archive-date=26 March 2021|archive-url=https://web.archive.org/web/20210326093527/https://www.ecdc.europa.eu/en/publications-data/geographical-distribution-confirmed-mers-cov-cases-country-infection-and-year|url-status=live}}{{Cite web|date=8 May 2021|title=Saudi Arabia reports 8th MERS case of 2021|url=http://outbreaknewstoday.com/saudi-arabia-reports-8th-mers-case-of-2021-2021/|access-date=5 June 2021|website=Outbreak News Today|archive-date=5 June 2021|archive-url=https://web.archive.org/web/20210605200816/http://outbreaknewstoday.com/saudi-arabia-reports-8th-mers-case-of-2021-2021/|url-status=dead}}

2013 dengue outbreak in Singapore

| 2013

| Singapore

| 8

2013 Vietnam measles outbreak

| 2013–2014

| Vietnam

Western African Ebola virus epidemic

| 142

| {{Cite news |url=https://www.smh.com.au/world/vietnam-measles-outbreak-kills-more-than-100-people-mostly-children-20140418-zqwkk.html |title=Vietnam measles outbreak kills more than 100 people, mostly children |date=18 April 2014 |work=Sydney Morning Herald |access-date=3 March 2020 |archive-date=3 March 2020 |archive-url=https://web.archive.org/web/20200303072443/https://www.smh.com.au/world/vietnam-measles-outbreak-kills-more-than-100-people-mostly-children-20140418-zqwkk.html |url-status=live }}

| 2013–2016

| Worldwide, primarily concentrated in Guinea, Liberia, Sierra Leone

| |Ebola

| data-sort-value="11301"| 11,323+

| {{Cite web|url=https://www.cdc.gov/vhf/ebola/history/2014-2016-outbreak/index.html|title=2014–2016 Ebola Outbreak in West Africa (section titled 'Impact')|date=2019-08-22|website=www.cdc.gov|language=en-us|access-date=2020-02-14|archive-date=2019-06-17|archive-url=https://web.archive.org/web/20190617162803/https://www.cdc.gov/vhf/ebola/history/2014-2016-outbreak/index.html|url-status=live}}{{Cite web |url=http://apps.who.int/gho/data/view.ebola-sitrep.ebola-summary-latest?lang=en |title=Situation summary Latest available situation summary, 26 June 2015. World Health Organization (2015-06-19). Retrieved on 2015-06-20. |access-date=27 June 2015 |archive-url=https://web.archive.org/web/20160605002217/http://apps.who.int/gho/data/view.ebola-sitrep.ebola-summary-latest?lang=en |archive-date=5 June 2016 |url-status=live}}{{Cite journal |last1=Gignoux |first1=Etienne |last2=Idowu |first2=Rachel |last3=Bawo |first3=Luke |last4=Hurum |first4=Lindis |last5=Sprecher |first5=Armand |last6=Bastard |first6=Mathieu |last7=Porten |first7=Klaudia |year=2015 |title=Use of Capture–Recapture to Estimate Underreporting of Ebola Virus Disease, Montserrado County, Liberia |journal=Emerging Infectious Diseases |volume=21 |issue=12 |pages=2265–2267 |doi=10.3201/eid2112.150756 |pmc=4672419 |pmid=26583831}}

2013–2014 chikungunya outbreak

| 2013–2015

| Americas

| Chikungunya

| 183

| {{Cite web |url=http://www.paho.org/hq/index.php?option=com_topics&view=article&id=343&Itemid=40931&lang=es |title=Número de casos informados de artritis epidémica chikungunya en las Américas – SE 5 (February 6, 2015) |publisher=Pan American Health Organization |access-date=February 11, 2015 |archive-url=https://web.archive.org/web/20150218071201/http://www.paho.org/hq/index.php?option=com_topics&view=article&id=343&Itemid=40931&lang=es |archive-date=February 18, 2015 |url-status=live}}

2013–19 avian influenza epidemic

| 2013–2019

| China

| Influenza A virus subtype H7N9

| 616

| {{Cite web |date=2019-12-04 |title=FAO H7N9 situation update – Avian Influenza A(H7N9) virus |url=http://www.fao.org/ag/againfo/programmes/en/empres/H7N9/situation_update.html |access-date=2020-06-10 |website=www.fao.org |archive-date=2020-06-17 |archive-url=https://web.archive.org/web/20200617211856/http://www.fao.org/ag/againfo/programmes/en/empres/H7N9/situation_update.html |url-status=live }}

21st century Madagascar plague outbreaks

| 2014–2017

| Madagascar

2014 Odisha hepatitis outbreak

| 292

| {{Cite web |url=https://www.who.int/csr/don/21-november-2014-plague/en/ |title=Plague – Madagascar |website=WHO |publisher=World Health Organization |access-date=5 July 2016 |archive-url=https://web.archive.org/web/20190502001426/https://www.who.int/csr/don/21-november-2014-plague/en/ |archive-date=2 May 2019 |url-status=dead}}

Flint water crisis

| 2014–2015

| Flint, Michigan, United States

| Legionnaires' disease

| 12

| {{Cite news|url=https://www.npr.org/sections/health-shots/2018/02/05/582482024/lethal-pneumonia-outbreak-caused-by-low-chlorine-in-flint-water|title=Lethal Pneumonia Outbreak Caused by Low Chlorine in Flint Water|newspaper=NPR.org|access-date=2021-06-16|archive-date=2023-07-11|archive-url=https://web.archive.org/web/20230711110132/https://www.npr.org/sections/health-shots/2018/02/05/582482024/lethal-pneumonia-outbreak-caused-by-low-chlorine-in-flint-water|url-status=live}}

| 2014–2015

| India

| Primarily Hepatitis E, but also Hepatitis A

| 36

|{{Cite news |url=http://www.deccanherald.com/content/460129/odisha-grapples-jaundice-outbreak.html |title=Odisha grapples with jaundice outbreak |date=17 February 2015 |work=Deccan Herald |access-date=17 February 2015 |archive-url=https://web.archive.org/web/20150217120135/http://www.deccanherald.com/content/460129/odisha-grapples-jaundice-outbreak.html |archive-date=17 February 2015 |url-status=live}}

2015 Indian swine flu outbreak

| 2015

| India

| Influenza A virus subtype H1N1

| data-sort-value="2035"|2,035

| {{Cite web |url=http://indianexpress.com/article/india/india-others/swine-flu-deaths-at-1895-cases-near-32k-mark/ |title=Swine flu deaths at 1895; number of cases near 32K mark |last=Press Trust of India |date=March 21, 2015 |publisher=The Indian Express |access-date=March 21, 2015 |archive-url=https://web.archive.org/web/20151012003206/http://indianexpress.com/article/india/india-others/swine-flu-deaths-at-1895-cases-near-32k-mark/ |archive-date=October 12, 2015 |url-status=live}}{{Cite news |url=https://www.bbc.com/news/world-asia-india-31547455 |title=India struggles with deadly swine flu outbreak |date=20 February 2015 |work=BBC News |access-date=21 February 2015 |archive-url=https://web.archive.org/web/20150221082410/http://www.bbc.com/news/world-asia-india-31547455 |archive-date=21 February 2015 |url-status=live}}{{Cite news |url=http://www.business-standard.com/article/pti-stories/swine-flu-claims-5-more-lives-toll-mounts-to-387-in-gujarat-115031500609_1.html |title=Death toll Gujarat |date=15 March 2015 |work=Business Standard |access-date=15 March 2015 |archive-url=https://web.archive.org/web/20150402093322/http://www.business-standard.com/article/pti-stories/swine-flu-claims-5-more-lives-toll-mounts-to-387-in-gujarat-115031500609_1.html |archive-date=2 April 2015 |url-status=live}}

2015–16 Zika virus epidemic

| 2015–2016

| Worldwide

| Zika virus

| 53

| {{cite web|url=https://www.worldwideoutbreak.com/blog/cool_timeline/2015-16-zika-virus-epidemic|title=2015–16 Zika Virus Epidemic|website=worldwideoutbreak|access-date=12 May 2020|archive-date=3 August 2020|archive-url=https://web.archive.org/web/20200803152135/https://www.worldwideoutbreak.com/blog/cool_timeline/2015-16-zika-virus-epidemic/|url-status=live}}

2016 Angola and Democratic Republic of the Congo yellow fever outbreak

| 2016

| Angola and Democratic Republic of the Congo

2016–2022 Yemen cholera outbreak

| 498 (377 in Angola, 121 in Congo)

| {{Cite web |url=http://www.promedmail.org/post/4123983 |title=Yellow fever – countries with dengue: alert 2016-03-28 20:39:56 Archive Number: Archive Number: 20160328.4123983 |website=ProMED-mail |publisher=International Society for Infectious Diseases |access-date=29 March 2016 |archive-url=https://web.archive.org/web/20160410065146/http://www.promedmail.org/post/4123983 |archive-date=10 April 2016 |url-status=live}}

| 2016–2023

| Yemen

2017 dengue outbreak in Peshawar

| data-sort-value="4004"|4,004 ({{as of|2023|6|11|lc=y|df=US}})

| {{Cite web|url=https://reliefweb.int/report/yemen/cholera-situation-yemen-december-2020|title=Cholera situation in Yemen, December 2020|website=reliefweb.int|publisher=World Health Organization|date=5 March 2021|access-date=21 May 2021|archive-date=13 May 2021|archive-url=https://web.archive.org/web/20210513160701/https://reliefweb.int/report/yemen/cholera-situation-yemen-december-2020|url-status=live}}

2017 Nigeria Lassa fever epidemic

| 2017–2023

| Nigeria

| Lassa fever

| 1103 (as of April 2023)

| {{Cite web|url=https://reliefweb.int/report/nigeria/ncdc-lassa-fever-situation-report-epi-week-18-03-09-may-2021|title=NCDC Lassa fever Situation Report Epi Week 18: 03 – 09 May 2021|date=9 May 2021|access-date=21 May 2021|archive-date=13 May 2021|archive-url=https://web.archive.org/web/20210513113918/https://reliefweb.int/report/nigeria/ncdc-lassa-fever-situation-report-epi-week-18-03-09-may-2021|url-status=live}}

| 2017

| Peshawar, Pakistan

2017 Gorakhpur hospital deaths

| 69

| {{cite web|url=https://reliefweb.int/disaster/ep-2017-000133-pak|publisher=WHO|title=Pakistan: Dengue Outbreak – Sep 2017|date=16 December 2019|access-date=15 May 2020|website=reliefweb.int|archive-date=3 August 2020|archive-url=https://web.archive.org/web/20200803063745/https://reliefweb.int/disaster/ep-2017-000133-pak|url-status=live}}

| 2017

| India

| Japanese encephalitis

| data-sort-value="1317"|1,317

| [https://www.indiatvnews.com/news/india-encephalitis-outbreak-gorakhpur-muzaffarpur-jev-aes-eastern-uttar-pradesh-northern-bihar-527836 Encephalitis outbreak: AES is a perennial issue in eastern Uttar Pradesh, northern Bihar] {{Webarchive|url=https://web.archive.org/web/20230711161944/https://www.indiatvnews.com/news/india-encephalitis-outbreak-gorakhpur-muzaffarpur-jev-aes-eastern-uttar-pradesh-northern-bihar-527836 |date=2023-07-11 }} Bihar's AES data summary looks more like a repeat of 2017 when a major JEV outbreak in Uttar Pradesh's Gorakhpur claimed the lives of many children. 17 June 2019 www.indiatvnews.com, accessed 17 February 2020

2017 dengue outbreak in Sri Lanka

| 2017

| Sri Lanka

2018 Nipah virus outbreak in Kerala

| 440

|{{Cite web|title=Trends|url=http://www.epid.gov.lk/web/index.php?option=com_casesanddeaths&Itemid=448&lang=en|access-date=2020-12-25|website=www.epid.gov.lk|archive-date=2020-04-09|archive-url=https://web.archive.org/web/20200409175345/http://www.epid.gov.lk/web/index.php?option=com_casesanddeaths&Itemid=448&lang=en|url-status=live}}

| 2018

| India

| Nipah virus infection

| data-sort-value="17"| 17

| {{Cite news|url=https://www.thenewsminute.com/article/nipah-virus-contained-last-two-positive-cases-have-recovered-kerala-health-min-82809|title=Nipah virus contained, last two positive cases have recovered: Kerala Health Min|date=2018-06-11|work=The News Minute|access-date=2020-02-16|archive-date=2019-02-08|archive-url=https://web.archive.org/web/20190208224936/https://www.thenewsminute.com/article/nipah-virus-contained-last-two-positive-cases-have-recovered-kerala-health-min-82809|url-status=live}}

Kivu Ebola epidemic

| 2018–2020

| Democratic Republic of the Congo and Uganda

2019–2020 measles outbreak in the Democratic Republic of the Congo

| data-sort-value="2271"| 2,280

|{{cite web|title=Operations Dashboard for ArcGIS|url=https://who.maps.arcgis.com/apps/opsdashboard/index.html#/e70c3804f6044652bc37cce7d8fcef6c|website=who.maps.arcgis.com|date=25 June 2020|access-date=28 June 2020|archive-date=21 August 2019|archive-url=https://web.archive.org/web/20190821210526/https://who.maps.arcgis.com/apps/opsdashboard/index.html#/e70c3804f6044652bc37cce7d8fcef6c|url-status=live}}{{Cite web |url=https://www.afro.who.int/publications/ebola-virus-disease-outbreak-uganda-situation-reports |title=Ebola Virus Disease Outbreak Uganda Situation Reports |website=WHO {{!}} Regional Office for Africa |language=en |access-date=3 September 2019 |archive-url=https://web.archive.org/web/20190620130334/https://www.afro.who.int/publications/ebola-virus-disease-outbreak-uganda-situation-reports |archive-date=20 June 2019 |url-status=live}}{{cite web |title=DR Congo's deadliest Ebola outbreak declared over |url=https://www.bbc.com/news/world-africa-53179323 |website=BBC News |access-date=25 June 2020 |date=25 June 2020 |archive-date=31 December 2020 |archive-url=https://web.archive.org/web/20201231180943/https://www.bbc.com/news/world-africa-53179323 |url-status=live }}

2018 NDM-CRE outbreak in Italy

| 2018–2019

| Italy

| New Delhi metallo-beta-lactamase-producing Carbapenem-resistant enterobacteriaceae

| 31 (as of September 2019)

|{{Cite web|url=https://www.ndtv.com/world-news/superbug-that-surfaced-in-delhi-strikes-in-italys-tuscany-2100068|title=Superbug That Surfaced In Delhi Strikes In Italy's Tuscany|date=12 September 2019|access-date=8 February 2021|website=ndtv.com|archive-date=25 December 2021|archive-url=https://web.archive.org/web/20211225042826/https://www.ndtv.com/world-news/superbug-that-surfaced-in-delhi-strikes-in-italys-tuscany-2100068|url-status=live}}

| 2019–2020

2019–2020 New Zealand measles outbreak

| 7,018+

| {{Cite news |url=http://outbreaknewstoday.com/drc-more-ebola-and-plague-cases-reported-end-of-measles-epidemic-declared-74655/ |title=DRC: More Ebola and plague cases reported, End of measles epidemic declared |language=en |access-date=2020-09-07 |archive-date=2020-08-30 |archive-url=https://web.archive.org/web/20200830182855/http://outbreaknewstoday.com/drc-more-ebola-and-plague-cases-reported-end-of-measles-epidemic-declared-74655/ |url-status=dead }}

| 2019–2020

| New Zealand

2019 measles outbreak in the Philippines

| 2

| {{Cite web |date=24 February 2020 |title=Measles weekly report |url=https://surv.esr.cri.nz/PDF_surveillance/MeaslesRpt/2020/measlesReport20200210.pdf |access-date=4 March 2021 |website=Public Health Surveillance |archive-date=19 February 2020 |archive-url=https://web.archive.org/web/20200219000610/https://surv.esr.cri.nz/PDF_surveillance/MeaslesRpt/2020/measlesReport20200210.pdf |url-status=dead }}

| 2019

| Philippines

2019 Kuala Koh measles outbreak

| 415

| {{cite news |last1=Tomacruz |first1=Sofia |title=At least 70 deaths due to measles – DOH |url=https://www.rappler.com/nation/223208-doh-report-deaths-due-to-measles-february-2019 |access-date=11 February 2019 |work=Rappler |date=11 February 2019}}

| 2019

| Kuala Koh, Malaysia

2019 Samoa measles outbreak

| 15

| {{cite web|url=https://says.com/my/news/mysterious-illness-causing-deaths-of-kampung-kuala-koh-orang-asli-identified-as-measles|title=A Measles Outbreak Is The Cause of 15 Orang Asli Deaths In Kelantan|first=Alyssa J.|last=Oon|publisher=Says.com|date=17 June 2019|access-date=27 August 2019|archive-url=https://web.archive.org/web/20190827033231/https://says.com/my/news/mysterious-illness-causing-deaths-of-kampung-kuala-koh-orang-asli-identified-as-measles|archive-date=27 August 2019|url-status=live}}

| 2019

| Samoa

2019–2020 dengue fever epidemic

| 83

| {{cite news|url=https://www.rnz.co.nz/international/pacific-news/406802/two-more-deaths-from-measles-in-samoa-over-new-year-period|title=Two more deaths from measles in samoa over new year period|date=2020-01-07|work=Radio New Zealand|url-status=live|archive-url=https://web.archive.org/web/20200107105921/https://www.rnz.co.nz/international/pacific-news/406802/two-more-deaths-from-measles-in-samoa-over-new-year-period|archive-date=2020-01-07}}

| 2019–2020

| Asia-Pacific, Latin America

2020 Democratic Republic of the Congo Ebola outbreak

| data-sort-value="3,931" | 3,931

| {{cite news |title=Dengue and severe dengue |url=https://www.who.int/news-room/fact-sheets/detail/dengue-and-severe-dengue |work=World Health Organization (WHO) |date=2 March 2020}}

style="font-weight: bold;"

| COVID-19 pandemic

| 2019{{efn|The COVID-19 pandemic started as a regional outbreak/epidemic of COVID-19 in China in late 2019. The World Health Organization referred to it as a "pandemic" on 11 March 2020.{{cite web |title=WHO Director-General's opening remarks at the media briefing on COVID-19 – 11 March 2020 |url=https://www.who.int/director-general/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19---11-march-2020 |website=World Health Organization |language=en}} The starting time of this epidemic is thus 2019, regardless of the time when it became a pandemic.|name="COVID2"}}–present

| Worldwide

| COVID-19

| data-sort-value="15000000 | 7.1–36.5 million

| {{#invoke:cite news

title=The pandemic's true death toll |newspaper=The Economist |url=https://www.economist.com/graphic-detail/coronavirus-excess-deaths-estimates |archive-url=https://web.archive.org/web/20240208015904/https://www.economist.com/graphic-detail/coronavirus-excess-deaths-estimates|date=26 July 2023|archive-date=8 February 2024}}

| 2020

2020 dengue outbreak in Singapore

| 55

| {{cite web |title=UNICEF welcomes end of Ebola outbreak in the Equateur Province of the DRC |url=https://www.unicef.org/press-releases/unicef-welcomes-end-ebola-outbreak-equateur-province-drc |website=www.unicef.org |access-date=18 November 2020}}

| 2020

| Singapore

| 32

| {{cite web |title=Dengue surveillance data, Oct – Dec 2020 |url=https://www.nea.gov.sg/docs/default-source/default-document-library/q4-2020-dengue-surveillance-data-(112kb).pdf |publisher=National Environment Agency}}

2020 Nigeria yellow fever epidemic

| 2020

| Nigeria

2021 South Sudan disease outbreak

| 296 (as of 31 December 2020)

| {{Cite web|last=|first=|date=31 Dec 2020|title=YELLOW FEVER SITUATION REPORT week 53 (December 31 2020)|url=https://ncdc.gov.ng/diseases/sitreps/?cat=10&name=An%20update%20of%20Yellow%20Fever%20outbreak%20in%20Nigeria|access-date=27 Jan 2021|website=Nigeria Centre for Disease Control}}

|2021

|South Sudan

|Unknown

|97 (as of December 2021)

|{{Cite web |last=Heilman |first=Greg |date=2021-12-24 |title=What disease does WHO say is causing deaths in South Sudan? |url=https://en.as.com/en/2021/12/24/latest_news/1640353876_492073.html |access-date=2022-10-24 |website=Diario AS |language=en}}

2021 India black fungus epidemic

| 2021–2022

| India

| Black fungus (COVID-19 condition)

| 4,332

| {{Cite web|date=22 July 2021|title=India reports 45,374 Black fungus cases, 4,332 deaths so far, says Health Ministry|url=https://www.aninews.in/news/national/general-news/india-reports-45374-black-fungus-cases-4332-deaths-so-far-says-health-ministry20210722140700/|access-date=22 July 2021|website=Asian News International}}

2022 hepatitis of unknown origin in children

| 2021–2022

| Worldwide

| Hepatitis by Adenovirus variant AF41 (Unconfirmed)

| strong|18

| {{Cite web|title=Mystery liver disease kills three more children after "unexpected significant increase" in cases reported|url=https://www.cbsnews.com/news/hepatitis-children-3-deaths-indonesia/|website=CBS News|date=3 May 2022 }}{{Cite web|title=CDC investigating 109 cases of severe hepatitis in kids across two dozen states, including 5 deaths|url=https://www.cnbc.com/2022/05/06/cdc-investigating-severe-hepatitis-in-children.html|website=CNBC|date=6 May 2022 }}{{Cite news|title=UPDATE: Israel report death of a child as Acute Hepatitis cases rise to 228 cases in mysterious global outbreak|url=https://euroweeklynews.com/2022/05/04/who-acute-hepatitis-cases-in-children-rise-to-228-cases-in-mysterious-global-outbreak/|website=Euro Weekly News|date=4 May 2022 }}

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| 2022–2024 Southern Africa cholera outbreak

| 2022–present

| Southern Africa

2022 Uganda Ebola outbreak

| 3000+

|{{cite web|url=https://www.unicef.org/esa/reports/cholera-outbreak-eastern-and-southern-africa-2023|title=The cholera outbreak in Eastern and Southern Africa isn't just an outbreak, it's an emergency for children|work=UNICEF|date=2023}}

2022–2023 mpox outbreak

| 2022–2023

| Worldwide

| Mpox

| 280

|{{cite web |last1=Steenhuysen |first1=Julie |title=Texas reports first U.S. death in person with monkeypox |url=https://www.reuters.com/world/us/texas-reports-first-us-death-person-with-monkeypox-2022-08-30/ |website=Reuters |language=en |date=30 August 2022}}{{cite web |last1=Faus |first1=Joan |title=Spain reports second monkeypox-related death in Europe |url=https://www.reuters.com/world/europe/spain-confirms-first-monkeypox-related-death-country-reports-2022-07-29/ |website=Reuters |access-date=9 September 2022 |language=en |date=30 July 2022}}{{cite web |title=Monkeypox |url=https://africacdc.org/wp-content/uploads/2022/08/AfricaCDC_MonkeypoxBrief5_11Aug22_EN.docx.pdf |website=African CDC |access-date=9 September 2022}}{{cite web |title=RDC : 3 décès et 69 nouveaux cas de Variole de singe enregistrés au Sankuru |url=https://actualite.cd/2022/08/12/rdc-3-deces-et-69-nouveaux-cas-de-variole-de-singe-enregistres-au-sankuru |website=Actualite.cd |access-date=9 September 2022 |language=fr |date=12 August 2022}}

| 2022–2023

| Uganda

| Sudan ebolavirus

| 77

|{{cite web |title=Ebola outbreak in Uganda declared over |url=https://bnonews.com/index.php/2023/01/ebola-outbreak-in-uganda-declared-over/ |website=BNO News |access-date=11 January 2023 |language=en |date=11 January 2023}}

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| 2023–2024 Zambian cholera outbreak (part of the 2022–2024 Southern Africa cholera outbreak)

| 2023–present

| Zambia

| 2023–2024 Bangsamoro measles outbreak

| 685

|{{cite web|url=https://www.unicef.org/zambia/stories/cholera-threatens-lives-zambia|title=Cholera Threatens Lives of Children and their Families in Parts of Zambia|work=UNICEF}}

2023 South Poland Legionellosis outbreak

|2023

|Poland

|Legionnaires' disease

|41

|{{cite web |title=Legionellosis – Poland |url=https://www.who.int/emergencies/disease-outbreak-news/item/2023-DON487 |website=www.who.int |access-date=16 January 2024 |language=en}}{{cite news |title=Poland: Legionnaire's bacteria outbreak kills 19 – DW – 09/02/2023 |url=https://www.dw.com/en/poland-legionnaires-bacteria-outbreak-kills-19/a-66704372 |access-date=27 September 2023 |work=dw.com |language=en}}

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| African mpox epidemic

| 2023–present

| Worldwide, primarily Africa

| Mpox

| 812

|{{cite web|url=https://www.wsj.com/world/africa/mpox-africa-who-global-health-emergency-f96d1033 |title=Rapid Spread of Mpox in Africa Is Global Health Emergency, WHO Says |website=www.wsj.com |access-date=2024-08-16}}

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| 2023–present

| Bangsamoro, Philippines