Little Cholame Creek

{{Use American English|date=February 2025}}

{{Infobox river

| name = Little Cholame Creek

| name_native =

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| image = little-cholame-creek.jpg

| image_caption = Little Cholame Creek at crossing over San Andreas Fault

| image_size = 300

| map =

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| pushpin_map = USA California

| pushpin_map_size = 300

| pushpin_map_caption= Location of the mouth of Little Cholame Creek in California

| subdivision_type1 = Country

| subdivision_name1 = United States

| subdivision_type2 = State

| subdivision_name2 = California

| subdivision_type3 = Region

| subdivision_name3 = Monterey County

| subdivision_type4 =

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| subdivision_type5 = City

| subdivision_name5 = Parkfield, California

| length = {{convert|8|mi|km|abbr=on}}

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| source1 = On the southern flank of an unnamed peak in the southern part of the Diablo Range

| source1_location =

| source1_coordinates= {{coord|35|59|13|N|120|31|09|W|display=inline}}{{cite gnis |id=244906 |name=Little Cholame Creek}}

| source1_elevation = {{convert|2690|ft|abbr=on}}

| mouth = Parkfield, California

| mouth_location =

| mouth_coordinates = {{coord|35|54|32|N|120|31|09|W|display=inline,title}}

| mouth_elevation = {{convert|1560|ft|abbr=on}}

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| tributaries_left = Reason Mountain, Pine Canyon Creek, Joaquin Canyon Creek

| tributaries_right = Middle Mountain Ridge

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Little Cholame Creek is a perennial stream in southeastern Monterey County, California, United States. The headwaters rise from an unnamed peak {{convert|2|mi|km|0|lk=off|abbr=off}} southwest of Reason Mountain, in the southern part of the Diablo Range. From there, the creek flows southeast along Parkfield-Coalinga Road, before reaching confluence with Cholame Creek.