Los Amigos River

{{Refimprove|date=November 2017}}

{{Infobox river

| name = Los Amigos River

| image =

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| map = Rivers of Madre de Dios.png

| map_size =

| map_alt =

| map_caption = The Madre de Dios watershed, including Los Amigos

| source1_location =

| mouth_location = Madre de Dios River

| subdivision_type1 = Country

| subdivision_name1 = Peru

| length =

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| discharge1_avg =

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}}

The Los Amigos River ("Friends River", Spanish: Río los Amigos) is a river that flows through the Amazon rainforest in the Madre de Dios Region in southeastern Peru. It is a tributary of the 1,347 km long Madre de Dios River.