MA-10 cell

MA-10 cells are a model cell line derived from the mouse Leydig cell tumor used in biomedical research.{{cite journal|last1=Rahman|first1=Nafis A |last2=Huhtaniemi |first2=Ilpo T |title=Testicular cell lines |journal=Mol Cell Endocrinol |date=30 December 2004 |volume=228 |issue=1–2 |pages=53–65 |pmid=15541572 |doi=10.1016/j.mce.2003.05.001}} The cell line is a luteinizing hormone-dependent steroidogenic cell line that was generated from a mice inbred strain C57BL/6J.{{cite journal|last1=ASCOLI|first1=MARIO|title=Characterization of several clonal lines of cultured Leydig tumor cells: gonadotropin receptors and steroidogenic responses|journal=Endocrinology|date=1 Jan 1981|volume=108|issue=1|pages=88–95|pmid=6257492 |doi=10.1210/endo-108-1-88|doi-access=free}} MA-10 cells are the most widely used of Leydig cell lines, and contributed much to our knowledge in Leydig cell steroid formation and regulation.{{cite journal | journal=Biology of Reproduction |year=2018 |volume=99|issue=1 |pages=101–11 | doi= 10.1093/biolre/ioy059 | title=Leydig cells: formation, function, and regulation |vauthors= Zirkin BR, Papadopoulos V | pmid=29566165 | pmc=6044347 }}