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MAB21L2

{{Short description|Protein-coding gene in the species Homo sapiens}}

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Mab-21-like 2 (C. elegans) is a protein that in humans is encoded by the MAB21L2 gene.{{cite web | title = Entrez Gene: Mab-21-like 2 (C. elegans) | url = https://www.ncbi.nlm.nih.gov/gene/10586 }}

Function

This gene is similar to the C. elegans MAB-21 cell fate-determining gene, a downstream target of transforming growth factor-beta signaling. It is thought that this gene may be involved in neural development. The protein encoded by this gene is primarily nuclear, although some cytoplasmic localization has been observed. [provided by RefSeq, Jul 2008].

References

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Further reading

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  • {{cite journal | vauthors = Mariani M, Baldessari D, Francisconi S, Viggiano L, Rocchi M, Zappavigna V, Malgaretti N, Consalez GG | title = Two murine and human homologs of mab-21, a cell fate determination gene involved in Caenorhabditis elegans neural development | journal = Human Molecular Genetics | volume = 8 | issue = 13 | pages = 2397–406 | date = December 1999 | pmid = 10556287 | doi = 10.1093/hmg/8.13.2397 | doi-access = free | hdl = 11380/1249629 | hdl-access = free }}

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